14 resultados para DNA Error Correction

em Chinese Academy of Sciences Institutional Repositories Grid Portal


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In recognition-based user interface, users’ satisfaction is determined not only by recognition accuracy but also by effort to correct recognition errors. In this paper, we introduce a crossmodal error correction technique, which allows users to correct errors of Chinese handwriting recognition by speech. The focus of the paper is a multimodal fusion algorithm supporting the crossmodal error correction. By fusing handwriting and speech recognition, the algorithm can correct errors in both character extraction and recognition of handwriting. The experimental result indicates that the algorithm is effective and efficient. Moreover, the evaluation also shows the correction technique can help users to correct errors in handwriting recognition more efficiently than the other two error correction techniques.

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DNA装配问题是指把各个读出序列(reads)拼接成一条完整的DNA链,即确定原DNA链的核苷酸“A,T,C,G”的排列顺序。实验中,由于各种原因测出的读出片段序列与DNA链的实际结果会有误差,这些误差会影响到用于装配的算法的性能,因此需要对测出的读出序列进行纠错。现有的算法如: ECINDEL和SRCorr都能够对实验数据进行纠错。但是它们都是根据某个读出序列出现的次数来判断它的正确性。这类算法首先选择参数k和M,若读出序列所有长度为k的子串出现的次数均大于M次,则它为正确的读出序列,即确实为原DNA链的子串。同时,还可以利用这些长度为k的子串来对原来的读出序列片段进行纠错。 然而,在这些算法中,M的选择要么是一个固定值,要么是随机的,使得这些算法在纠错问题上的表现并不稳定。 本文我们计算长度为k的子串出现M次时,它的真阳性(确实为原DNA链的一部分)的概率以及假阳性和假阴性的概率。根据计算结果,我们可以选择一个最优的M值使得最后选取的子串的错误最少,即假阳性的子串与假阴性的子串的数量之和最少。我们在模拟数据和实际数据上进行了验证,与之前的纠错算法ECINDEL,SRCorr相比,我们的算法总的错误率降低了77.6%和65.1%。

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分析了RS(Reed-Solomon)纠错码和网格编码调制(Trellis Coded Modulation,TCM)技术在光脉冲位置调制通信中的应用.在此基础上,提出了以RS码作为外码,以网格编码调制技术作为内码,用于光脉冲位置调制通信的新编码方案,能以几乎不减少通信速率的优势,提高传统RS码系统在时变带限光信道中的通信性能.模拟研究了在不同空间光信道条件下,传统RS码的符号正确传输率和误码率,并对网格编码调制的编码增益、RS码与网格编码调制级联时的编码增益进行了仿真研究,证实了本方案的有效性.

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文中介绍的误差自修正方法是通过光栅位移测量系统中单片机对光栅传感器的多个零位信号进行计数,并根据测量值和系统设定值得到的误差函数自动进行误差修正。实验结果表明,该方法对光栅位移测量系统的误差既可自动进行有效的修正,又可提高系统的测量精度。

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A differential recursive scheme for suppression of Peak to average power ratio (PAPR) for Orthogonal frequency division multiplexing (OFDM) signal is proposed in this thesis. The pseudo-randomized modulating vector for the subcarrier series is differentially phase-encoded between successive components in frequency domain first, and recursion manipulates several samples of Inverse fast Fourier transformation (IFFT) output in time domain. Theoretical analysis and experimental result exhibit advantage of differential recursive scheme over direct output scheme in PAPR suppression. And the overall block diagram of the scheme is also given.

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This paper proposes a novel and innovative scheme for 10Gb/s parallel Very Short Reach (VSR) optical communication system. The optimized scheme properly manages the SDH/SONET redundant bytes and adjusts the position of error detecting bytes and error correction bytes. Compared with the OIF-VSR4-01.0 proposal, the scheme has a coding process module. The SDH/SONET frames in transmission direction are disposed as follows: (1) The Framer-Serdes Interface (FSI) gets 16x622.08Mb/s STM-64 frame. (2) The STM-64 frame is byte-wise stripped across 12 channels, all channels are data channels. During this process, the parity bytes and CRC bytes are generated in the similar way as OIF-VSR4-01.0 and stored in the code process module. (3) The code process module will regularly convey the additional parity bytes and CRC bytes to all 12 data channels. (4) After the 8B/10B coding, the 12 channels is transmitted to the parallel VCSEL array. The receive process approximately in reverse order of transmission process. By applying this scheme to 10Gb/s VSR system, the frame size in VSR system is reduced from 15552x12 bytes to 14040x12 bytes, the system redundancy is reduced obviously.

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用识别技术的用户界面往往由于识别率的限制容易出错,如何为这类界面提供自然高效的纠错方法十分重要.手写数学公式具有二维结构,难以识别和纠错.提出一种用于纠正手写数学公式识别错误的多通道技术.它允许用户使用笔纠正切分错误,用笔和语音纠正符号识别和表达式结构分析错误.该技术的核心是一个多通道融合算法.融合算法以笔选择的符号和语音作为输入,根据语音输入的类型是数学术语或者数学符号分别选择融合方法,最后修正手写公式并输出最有可能的识别结果.实验结果表明,该技术能有效地纠正手写数学公式识别中的错误,它比基于笔的单通道纠错技术更加高效.

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在基于识别的界面中,用户的满意度不但由识别准确度决定,而且还受识别错误的纠正过程的影响.提出一种基于多通道融合的连续手写笔迹识别错误的纠正方法.该方法允许用户通过口述书写内容纠正手写识别中的字符提取和识别的错误.该纠错方法的核心是一种多通道融合算法.该算法通过利用语音输入约束最优手写识别结果的搜索,可纠正手写字符的切分错和识别错.实验评估结果表明,该融合算法能够有效纠正错误,计算效率高.与另外两种手写识别错误纠正方法相比,该方法具有更高的纠错效率.

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提出了一种基于信道估计的RS纠错编码改进算法,该算法可以自适应地根据外界条件和环境对传输信道的干扰变化实时地调节编码系统的数据冗余量。仿真与完整的分析结果证实了该改进算法有效地改善了RS编码算法的传输效率;并且通过实际应用表明:良好的性能,高容错性适应于该通信系统的多种传输信道,具有很强的实用性。

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The alternate combinational approach of genetic algorithm and neural network (AGANN) has been presented to correct the systematic error of the density functional theory (DFT) calculation. It treats the DFT as a black box and models the error through external statistical information. As a demonstration, the AGANN method has been applied in the correction of the lattice energies from the DFT calculation for 72 metal halides and hydrides. Through the AGANN correction, the mean absolute value of the relative errors of the calculated lattice energies to the experimental values decreases from 4.93% to 1.20% in the testing set. For comparison, the neural network approach reduces the mean value to 2.56%. And for the common combinational approach of genetic algorithm and neural network, the value drops to 2.15%. The multiple linear regression method almost has no correction effect here.

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A circular bacterial artificial chromosome of 148.9 kbp on human chromosome 3 has been extended and fixed on bare mica substrates using a developed fluid capillary flow method in evaporating liquid drops. Extended circular DNA molecules were imaged with an atomic force microscope (AFM) under ambient conditions. The measured total lengths of the whole DNA molecules were in agreement with sequencing analysis data with an error range of +/-3.6%. This work is important groundwork for probing single nucleotide polymorphisms in the human genome, mapping genomic DNA, manipulating biomolecular nanotechnology, and studying the interaction of DNA-protein complexes investigated by AFM.

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Target transformation factor analysis was used to correct spectral interference in inductively coupled plasma atomic emission spectrometry (ICP-BES) for the determination of rare earth impurities in high purity thulium oxide. Data matrix was constructed with pure and mixture vectors and background vector. A method based on an error evaluation function was proposed to optimize the peak position, so the influence of the peak position shift in spectral scans on the determination was eliminated or reduced. Satisfactory results were obtained using factor analysis and the proposed peak position optimization method.

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The present paper reports some definite evidence for the significance of wavelength positioning accuracy in multicomponent analysis techniques for the correction of line interferences in inductively coupled plasma atomic emission spectrometry (ICP-AES). Using scanning spectrometers commercially available today, a large relative error, DELTA(A) may occur in the estimated analyte concentration, owing to wavelength positioning errors, unless a procedure for data processing can eliminate the problem of optical instability. The emphasis is on the effect of the positioning error (deltalambda) in a model scan, which is evaluated theoretically and determined experimentally. A quantitative relation between DELTA(A) and deltalambda, the peak distance, and the effective widths of the analysis and interfering lines is established under the assumption of Gaussian line profiles. The agreement between calculated and experimental DELTA(A) is also illustrated. The DELTA(A) originating from deltalambda is independent of the net analyte/interferent signal ratio; this contrasts with the situation for the positioning error (dlambda) in a sample scan, where DELTA(A) decreases with an increase in the ratio. Compared with dlambda, the effect of deltalambda is generally less significant.

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The present paper deals with the evaluation of the relative error (DELTA(A)) in estimated analyte concentrations originating from the wavelength positioning error in a sample scan when multicomponent analysis (MCA) techniques are used for correcting line interferences in inductively coupled plasma atomic emission spectrometry. In the theoretical part, a quantitative relation of DELTA(A) with the extent of line overlap, bandwidth and the magnitude of the positioning error is developed under the assumption of Gaussian line profiles. The measurements of eleven samples covering various typical line interferences showed that the calculated DELTA(A) generally agrees well with the experimental one. An expression of the true detection limit associated with MCA techniques was thus formulated. With MCA techniques, the determination of the analyte and interferent concentrations depend on each other while with conventional correction techniques, such as the three-point method, the estimate of interfering signals is independent of the analyte signals. Therefore. a given positioning error results in a larger DELTA(A) and hence a higher true detection limit in the case of MCA techniques than that in the case of conventional correction methods. although the latter could be a reasonable approximation of the former when the peak distance expressed in the effective width of the interfering line is larger than 0.4. In the light of the effect of wavelength positioning errors, MCA techniques have no advantages over conventional correction methods unless the former can bring an essential reduction ot the positioning error.