46 resultados para epoc® blood analysis system
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Mesoscale eddy plays an important role in the ocean circulation. In order to improve the simulation accuracy of the mesoscale eddies, a three-dimensional variation (3DVAR) data assimilation system called Ocean Variational Analysis System (OVALS) is coupled with a POM model to simulate the mesoscale eddies in the Northwest Pacific Ocean. In this system, the sea surface height anomaly (SSHA) data by satellite altimeters are assimilated and translated into pseudo temperature and salinity (T-S) profile data. Then, these profile data are taken as observation data to be assimilated again and produce the three-dimensional analysis T-S field. According to the characteristics of mesoscale eddy, the most appropriate assimilation parameters are set up and testified in this system. A ten years mesoscale eddies simulation and comparison experiment is made, which includes two schemes: assimilation and non-assimilation. The results of comparison between two schemes and the observation show that the simulation accuracy of the assimilation scheme is much better than that of non-assimilation, which verified that the altimetry data assimilation method can improve the simulation accuracy of the mesoscale dramatically and indicates that it is possible to use this system on the forecast of mesoscale eddies in the future.
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随着国内金融行业的逐步开放,中国银联也面临着跨国银行卡组织的激烈竞争,跨国银行卡组织拥有先进的IT技术和经营管理经验,和中国银联相比,具有很大竞争优势。银联为了积极面对跨国银行卡组织的挑战,成为一个知名品牌,必须加快信息化建设,转变经营观念,从传统的以业务为中心转移到以客户为中心,而商业智能技术——数据仓库和数据挖掘正是银联信息化建设的重要保障。 本文首先分析了银联的实际业务需求,结合银联的具体业务特点,设计与实现了银联的数据仓库系统,着重对数据仓库技术在银联中的应用现状进行了详细表述;该系统采用总线式的设计架构,有很好的一致性和可扩展性;系统采用维度建模方法进行数据仓库的逻辑设计,维度建模方法能很好地提高系统查询性能,在逻辑设计基础上本文也进行了数据仓库的物理设计。同时本文也详细介绍了数据仓库的重点部分——ETL系统的设计和实现,该ETL系统采用模块化的设计方法,采用元数据作为驱动方式,加强了调度管理和监控的功能,使该ETL工具更具智能性和更好的适应性。 本文在完成银联数据仓库系统建设的基础上,详细分析了银联业务系统要实现的OLAP分析目标,介绍了数据挖掘技术在银联客户分类中的应用,首次尝试在银联数据仓库系统中构建客户分类模型。在客户分类模型的构建中,我们首先采用聚类技术进行客户群分类,然后使用改进的SLIQ算法构建分类模型,本文对SLIQ算法中的符号型属性处理方法及其剪枝算法进行改进,并对结果进行对比分析,得到了一个较为合理的客户分类模型,取得了很好的应用效果,从而为银联数据仓库系统开发应用提供了可借鉴的操作思路。
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设计并实现了基于Pocket PC的互联网遥操作机器人足球比赛系统,按照需求分析、系统设计与实现,以及实验结果的思路描述了整个过程,建立了无线网络环境下遥操作理论研究的实验平台,并以此为基础对遥操作机器人足球背景下的操作者策略与自主智能的融合作了一些探索。
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在低挡微机中速度较慢的串行处理硬设备条件下,利用本文提出的启发式概念,分层搜索和匹配策略以及设置最大搜索长度等方法,可使推理速度提高一个数量级以上.此外,通过引入语义信息,分阶段消除歧义,自顶向下与自底向上相结合,以及把一般疑问句一律变成相应陈述句的方法,解决了自动英语句法分析中的一系列难题,缩小了知识库的规模。
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在基因芯片分析系统中,基因芯片荧光靶点图像的正确检测识别是基因特异性表达信息提取的必要前提。在荧光靶点检测识别过程中,由于沾污、瑕疵、离焦等因素的影响,荧光靶点图像的信噪比很低,很容易将污点、基片瑕疵等噪声点误识别为荧光靶点,而将沾污的荧光靶点误识别为噪声点。在原算法基础上,为进一步降低误识别率和提高检测精度,提出基于靶点分割图像重心和目标背景面积比的改进的荧光靶点检测识别算法。实验结果表明,与原算法相比,采用新算法将正确识别率提高到90%以上。
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文章介绍了一个基于虚拟仪器技术开发的变速箱振动测试与分析系统。该系统实现了汽车变速箱振动信号的检测、分析、处理和显示存储,满足对测试过程高精度、自动化、智能化等各项测试要求。
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The engineering geological properties of Neogene hard clays and related engineering problems are frontiers in the fields of Engineering Geology, Soil Mechanics and Rock Mechanics. Recently, it has been recognized that Neogene hard clay is the intermediate type of material between the soil and the rock. Many aspects of them, such as sampling, testing, calculating and engineering process, are special, which could not be researched by means of theories and methods of traditional Soil Mechanics of Rock Mechanics. In order to get real knowledge and instruct the engineering practice, intersect studying of multiple disciplines, including Engineering Geology, Soil Mechanics and Rock Mechanics, etc., is necessary. Neogene hard clay is one of the important study objects of regional problem rocks & soils in our country, which extensively distributed in China, especially in Eastern China. Taking the related areas along the middle line of the Project of Transferring Water from the South to the North (e.g. Nanyang basin, Fangcheng-Baofeng area and Handan-Yongnian area), South-west of Shandong, Xu-Huai area and Beijing area, etc. as main study areas, the paper divided Neogene hard clays into reduction environment dominated origin and oxidation environment dominated origin, which distributed on areas western and eastern to Mount Taihangshan respectively. Intermediate types are also existed in some areas, which mainly distribute near the edges of depositional basins; they are usually of transitions between diluvial and lacustrine deposits. As to Neogene hard clays from Eastern China, the clay particle content is high, and montmorillonite or illite/montmorillonite turbostratic mineral is the dominating clay mineral. The content of effective montmorillonite is very high in each area, which is the basis for the undesirable engineering properties of Neogene hard clays. For hard clays from the same area, the content of effective montmorillonite in gray-greenish hard clay is much higher than that in purple-brownish or brown-yellowish hard clay, which is the reason why the gray-greenish hard clay usually has outstanding expansive property. On the other hand, purple-brownish or brown-yellowish hard clay has relatively less montmorillonite, so its property is better. All of these prove that the composition (clay mineral) of Neogene hard clay is the control factor for the engineering properties. Neogene hard clays have obvious properties such as fissured, overconsolidated and expansive, which are the main reasons that many engineering problems and geological harzards usually occur in Neogene hard clays. The paper systematically elaborates the engineering properties of Neogene hard clays from Eastern China, analyses the relationships between engineering properties and basic indexes. The author introduces the ANN method into the prediction of engineering property indexes of hard clays, which provides a new way for quantitatively assessment and prediction of engineering property indexes. During investigation in the field, the author found that there exists obvious seam-sheared zone between different hard clays in Miocene Xiacaowan formation in Xu-Huai area. Similar phenomenon also exists near the borderline between Neogene hard clays and underlying coal measures in the Southwest of Shandong province, which could be observed in the cores. The discovery of seam-sheard zone has important theoretical and practical significance for engineering stability analysis and revealing the origin of fissures in Neogene hard clays. The macrostructure, medium structure and microstructure together control the engineering properties of hard clays. The author analyses and summarizes the structural effects on hard clays in detail. The complex of the strength property of hard clays is mostly related to the characteristics of fissures, which is one of the main factors that affect the choice of shear strength parameters. So structure-control theory must be inseparably combined with composition-control theory during the engineering geological and rock/soil mechanics research of hard clays. The engineering properties, such as fissured, overconsolidated and expansive, control the instability of engineering behaviors of Neogene hard clays under the condition of excavation, i.e. very sensitive to the change of existence environment. Based on test data analysis, the author elaborates the effects of engineering environment change on the engineering properties. Taking Nanyang basin as example, the author utilizes FEM to study the effects of various factors on stability of cutting canal slopes, than sets forth the characteristics, development laws and formation mechanism of the deformation and failure of hard clay canal slopes, summarizes the protection and reinforcement principles, as well as the protection and remedy steps. On the basis of comparison of engineering properties of domestic and foreign Neogene muddy deposits, in the view of whole globe and associated with the geological characteristics of China, the paper demonstrates that the intermediate type of the material between the soil and the rock, named "hard clay/soft rock", which can not be separated abruptly, really exists in China. The author has given a preliminary classification based on its geological origin and distribution law, which is very significant for promoting the mixture of Engineering Geology, Soil Mechanics and Rock Mechanics. In the course of large scales engineering construction in China, many engineering experiences and testing data are gained, summarizing these testing results and automatically managing them with computer technology are very necessary. The author develops a software named "Hard Clay-Soft Rock Engineering Geological Information Management and Analysis System (HRGIMS)", realizes the automatic and visual management of geo-engineering information, on the basis of information management, the functions of test data analysis and engineering property prediction are strengthened. This system has well merits for practice and popularization.
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Synthetic Geology Information System(SGIS) is a part of the theory of Engineering Geomechanics-mate-Synthetics(EGMS), is also a development of its technical methodology. SGIS includes ways of geology engineering investigation, design, and construction. Although SGIS has an integrate theory frame, and some parts of it have gained great progress, the completion of SGIS is a continuous and accumulative process. This paper analyses the ways and principle of building knowledge database and model database, summarizes the experts' experience on exploration methods selection and the characters of exploration models, combining with the application of Decision Support System(DSS) in Decision support of Synthetic Exploration Methods for Railway engineering Geology. By the analysis of hierarchy structure of the model database, the effects of geology engineering factors on the selection of exploration methods are expressed. By the usage of fuzzy patterns recognize, hierarchy structure analysis, fuzzy collection closement analysis etc, the software of DSS for engineering design and construction are developed. At same time, by the development of Monitoring Data Analysis System and experiment data management system of Hydro-power project, this paper discussed the data management of science experiment of Hydro-power project by the usage of synthetic database and the usage of Geography Information System(GIS) and DSS technics. The technic of visual operation of data process and project monitoring system are presented. The intelligence algorithm of self-adoption is carried out to improve the data process and analysis of monitoring. Items of the project theoretical analysis and data process are designed in detail. All the theory and technical methods presented in this paper are one part of SGIS, in which the application of DSS and GIS, is an important step of the progress and completion of SGIS.
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Horseflies are economically important blood-feeding arthropods and also a nuisance for humans and vectors for filariasis. They rely heavily on the pharmacological properties of their saliva to get a blood meal and suppress immune reactions of hosts. Little information is available on antihemostatic substances in horsefly salivary glands; especially no horsefly immune suppressants have been reported. By proteomics or peptidomics and coupling transcriptome analysis with pharmacological testing, several families of proteins or peptides, which act mainly on the hemostatic system or immune system of the host, were identified and characterized from 30,000 pairs salivary glands of the horsefly Tabanus yao (Diptera, Tabanidae). They are: (i) a novel family of inhibitors of platelet aggregation including two members, which possibly inhibit platelet aggregation by a novel mechanism and act on platelet membrane, (ii) a novel family of immunosuppressant peptides including 12 members, which can inhibit interferon-gamma production and increase interleukin-10 secretion, (iii) a serine protease inhibitor with 56 amino acid residues containing anticoagulant activity, (iv) a serine protease with anticoagulant activity, (v) a protease with fibrinogenolytic activity, (vi) three families of antimicrobial peptides including six members, (vii) a hyaluronidase, (viii) a vasodilator peptide, which is an isoform of vasotab identified from Hybomitra bimaculata, and interestingly (ix) two metallothioneins, which are the first metallothioneins reported from invertebrate salivary glands. The current work will facilitate the understanding of the molecular mechanisms of the ectoparasite-host relationship and help in identifying novel vaccine targets and novel leading pharmacological compounds.
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A novel fish chemokine receptor gene, chemokine (C-X-C motif) receptor 3 (CXCR3)-like was isolated from the grass carp Ctenopharyngodon idella , with its full-length genomic sequence. The cDNA of grass carp CXCR3-like (gcCXCR3-like) consists of 1261 bp with a 49bp 5'-UTR and a 189 bp 3'-UTR. An open reading frame of 1023 bp encodes a 341-amino acid peptide, with seven transmembrane helices. The deduced amino acid sequence showed the same sequence identities (37.8%) with its counterparts in goat and human. The gcCXCR3-like gene consists of two exons, with one intervening intron, spaced over approximately 2 kb of genomic sequence. Phylogenetic analyses clearly demonstrated that the gcCXCR3-like resembles the CXCR3s of other vertebrates. Real-time PCR analysis showed that gcCXCR3-like was expressed in all tested organs except heart and the expression level of gcCXCR3-like was highest in brain. Flow cytometric analyses showed the positive rate of labelled leukocytes from the healthy grass carp was 17.3%, and the labelled leukocytes were divided into three types by cell sorting. Immunohistochemical localization revealed that gcCXCR3-like expressed in whole brain regions including cerebel, diencephalon, medulla oblongata, optic lobe, and rhinencephalon, and that the labelled leukocytes are actually populations of monocyte and/or phagocyte, lymphocyte and the granulocyte. It is considered that fish CXCR expression and their function may need to be investigated in both nervous and immune systems. (c) 2006 Elsevier Ltd. All rights reserved.
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Classical theories have successfully provided an explanation for convection in a liquid layer heated from below without evaporation. However, these theories are inadequate to account for the convective instabilities in an evaporating liquid layer, especially in the case when it is cooled from below. In the present paper, we study the onset of Marangoni convection in a liquid layer being overlain by a vapor layer.A new two-sided model is put forward instead of the one-sided model in previous studies. Marangoni-Bénard instabilities in evaporating liquid thin layers are investigated with a linear instability analysis. We define a new evaporation Biot number, which is different from that in previous studies and discuss the influences of reference evaporating velocity and evaporation Biot number on the vapor-liquid system. At the end, we explain why the instability occurs even when an evaporating liquid layer is cooled from below.
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Micro-fabrication technology has substantial potential for identifying molecular markers expressed on the surfaces of tissue cells and viruses. It has been found in several conceptual prototypes that cells with such markers are able to be captured by their antibodies immobilized on microchannel substrates and unbound cells are flushed out by a driven flow. The feasibility and reliability of such a microfluidic-based assay, however, remains to be further tested. In the current work, we developed a microfluidic-based system consisting of a microfluidic chip, an image grabbing unit, data acquisition and analysis software, as well as a supporting base. Specific binding of CD59-expressed or BSA-coupled human red blood cells (RBCs) to anti-CD59 or anti-BSA antibody-immobilized chip surfaces was quantified by capture efficiency and by the fraction of bound cells. Impacts of respective flow rate, cell concentration, antibody concentration and site density were tested systematically. The measured data indicated that the assay was robust. The robustness was further confirmed by capture efficiencies measured from an independent ELISA-based cell binding assay. These results demonstrated that the system developed provided a new platform to effectively quantify cellular surface markers effectively, which promoted the potential applications in both biological studies and clinical diagnoses.
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The natural reproduction of grass carp, black carp, silver carp, and bighead will be affected adversely by the Three Gorges Project in the Yangtze River. One of the methods to save the fish is to regulate the water levels, keeping them suited for the species to spawn. Nine factors associated with the scale of larvae-flood of the four species are classified into five levels, and the ranges of these factors producing larvae-floods are given by using the "factor-criteria system reconstruction analysis" method. Moderate beginning water levels and flow, with high daily increases in the rate of water level and flow, and a long duration of water level rising are important for the production of a large larvae-flood.