Helena de Eurípides y los roles de género

Le Rane : Collana di Studi e Testi. Studi ; 55 - El teatro clásico en el marco de la cultura griega y su pervivencia en la cultura occidental ; 13

Dietary animal and plant protein intakes and their associations with obesity and cardio-metabolic indicators in European adolescents: the HELENA cross-sectional study

Background: Previous studies suggest that dietary protein might play a beneficial role in combating obesity and its related chronic diseases. Total, animal and plant protein intakes and their associations with anthropometry and serum biomarkers in European adolescents using one standardised methodology across European countries are not well documented. Objectives: To evaluate total, animal and plant protein intakes in European adolescents stratified by gender and age, and to investigate their associations with cardio-metabolic indicators (anthropometry and biomarkers). Methods: The current analysis included 1804 randomly selected adolescents participating in the HELENA study (conducted in 2006-2007) aged 12.5-17.5 y (47% males) who completed two non-consecutive computerised 24-h dietary recalls. Associations between animal and plant protein intakes, and anthropometry and serum biomarkers were examined with General linear Model multivariate analysis. Results: Average total protein intake exceeded the recommendations of World Health Organization and European Food Safety Authority. Mean total protein intake was 96 g/d (59% derived from animal protein). Total, animal and plant protein intakes (g/d) were significantly lower in females than in males and total and plant protein intakes were lower in younger participants (12.5-14.9 y). Protein intake was significantly lower in underweight subjects and higher in obese ones; the direction of the relationship was reversed after adjustments for body weight (g/(kg.d)). The inverse association of plant protein intakes was stronger with BMI z-score and body fat percentage (BF%) compared to animal protein intakes. Additionally, BMI and BF% were positively associated with energy percentage of animal protein. Conclusions: This sample of European adolescents appeared to have adequate total protein intake. Our findings suggest that plant protein intakes may play a role in preventing obesity among European adolescents. Further longitudinal studies are needed to investigate the potential beneficial effects observed in this study in the prevention of obesity and related chronic diseases.

Azpiegitura proiektu handiak Euskal Autonomia Elkartean: bideragarritasuna eta baliagarritasuna

Gaur eguneko politika ekonomikoak aztertu ezkero berehala ohartuko ginateke azpiegitura - proiektuei ematen ari zaien garrantzi gero eta handiagoaz. Aurrekontuetan, beste zenbait kontusailetan murrizketak edo gutxienez mugaketak planteatzen ari diren bitartean azpiegituren ezarrerarako baliabide gehiago destinatzen dituzte. Eta ildo hau nagusitzen ari da esparru guztietan, europarretik hasita udal esparruraino. Artikulu honen helburua ez da izango gai honen sakoneko azterketa xehetu eta osatua eskeintzea, horrek luzez gaindituko bailuke aldizkari batetako idazlan batek bete dezaken funtzioa. Gure helburua, hortaz, askoz ere apalagoa izango da; zera da lortu nahi duguna: gure lurraldearentzat hain erabakior diren azpiegitura - proiektuei buruzko jakinmina sortaraztea irakurleongan, aurrerantzean interes eta arreta handiagoaz jarrai ditzaten gaiaren nondik norakoak, komunikabideek horren maiz zuzentzen diguten informazioaren bidez.

Dramatické texty přeložené a cenzurované ve frankistickém Španělsku (šedesátá léta): divadlo a film jako kontrolovaná představení

Texto en checo. Editora de la obra Petra Vavroušová.

Estrategias de Internacionalización en el sector hotelero: Estudio de casos

Este Trabajo de Fin de Grado se centra en el análisis de las principales estrategias de internacionalización de las dos cadenas hoteleras de mayor relevancia a nivel nacional: Meliá Hotels International y NH Hotel Group. Tras comenzar con un pequeño marco conceptual basado en la revisión bibliográfica de autores expertos en dirección estratégica e internacionalización, se ha procedido a realizar una investigación cualitativa: En primer lugar se describe el desarrollo de ambas compañías en el ámbito internacional hasta llegar a la actualidad, para proseguir con el análisis de sus actuales estrategias de internacionalización y formas de crecimiento. Por último se evalúan los resultados obtenidos y se dan a conocer sus futuras líneas de actuación a nivel internacional

La historia a través del cine. Transición y consolidación democrática en España

Índice: - El cambio político postfranquista en el cine de su tiempo: "El disputado voto del señor Cayo". - La primera generación del postfranquismo. - El País Vasco, ¿una transición diferente? "Sombras de una batalla". - El País Vasco: ¿la cuestión pendiente de la transición? "Yoyes" de Helena Taberna. - "Cría cuervos", la representación del universo femenino en una película de la transición. - La España de los 80 en el cine de Pedro Almodóvar. - Continuidades y cambios sociales en la transición y democracia. - España fin de milenio: sobre "El día de la bestia" (Alex de la Iglesia, 1995). - Otras películas sobre la transición y la etapa socialista.

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) genes. While allosteric inhibition of the mechanistic target of rapamycin (mTOR) has shown substantial clinical benefit, complementary therapies are required to improve response and/or to treat specific patients. However, there is a lack of LAM biomarkers that could potentially be used to monitor the disease and to develop other targeted therapies. We hypothesized that the mediators of cancer metastasis to lung, particularly in breast cancer, also play a relevant role in LAM. Analyses across independent breast cancer datasets revealed associations between low TSC1/2 expression, altered mTOR complex 1 (mTORC1) pathway signaling, and metastasis to lung. Subsequently, immunohistochemical analyses of 23 LAM lesions revealed positivity in all cases for the lung metastasis mediators fascin 1 (FSCN1) and inhibitor of DNA binding 1 (ID1). Moreover, assessment of breast cancer stem or luminal progenitor cell biomarkers showed positivity in most LAM tissue for the aldehyde dehydrogenase 1 (ALDH1), integrin-beta 3 (ITGB3/CD61), and/or the sex-determining region Y-box 9 (SOX9) proteins. The immunohistochemical analyses also provided evidence of heterogeneity between and within LAM cases. The analysis of Tsc2-deficient cells revealed relative over-expression of FSCN1 and ID1; however, Tsc2-deficient cells did not show higher sensitivity to ID1-based cancer inhibitors. Collectively, the results of this study reveal novel LAM biomarkers linked to breast cancer metastasis to lung and to cell stemness, which in turn might guide the assessment of additional or complementary therapeutic opportunities for LAM.