3 resultados para Operational organization

em Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco


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Revised 2006-06

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[ES] Este trabajo presenta la problemática de la gestión del riesgo operativo en las entidades de crédito en el ámbito europeo. Aprobado el texto definitivo del denominado Comité de Supervisión Bancaria (Basilea II), con especial y novedosa regulación del riesgo operativo, amanece como inminente su integración e la regulación bancaria de la UE, y, por tanto, su pronta implantación y supervisión por las autoridades monetarias y financieras. Esta nueva normativa, de carácter flexible y profesional, introduce en el seno del gobierno corporativo de las entidades de crédito nuevos elementos que afectarán a su cultura interna (cultura de gestión de los riesgos), afectando a las decisiones estratégicas y a la organización de las entidades, incentivando a la mejora de la calidad de sus procesos, servicios y operaciones. Todo lo cual supone una acicate para perseguir la eficiencia continua a nivel individual y a nivel del sistema financiero, con visos de adquirir dimensión estratégica. De esta manera, se abre un espacio para la investigación y creatividad en la aplicación y desarrollo de los postulados científicos de la Economía de la Empresa, con posibilidades de incorporarlos a otros sectores empresariales de similar afectación por los riesgos operativos.

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Background: Over many years, it has been assumed that enzymes work either in an isolated way, or organized in small catalytic groups. Several studies performed using "metabolic networks models'' are helping to understand the degree of functional complexity that characterizes enzymatic dynamic systems. In a previous work, we used "dissipative metabolic networks'' (DMNs) to show that enzymes can present a self-organized global functional structure, in which several sets of enzymes are always in an active state, whereas the rest of molecular catalytic sets exhibit dynamics of on-off changing states. We suggested that this kind of global metabolic dynamics might be a genuine and universal functional configuration of the cellular metabolic structure, common to all living cells. Later, a different group has shown experimentally that this kind of functional structure does, indeed, exist in several microorganisms. Methodology/Principal Findings: Here we have analyzed around 2.500.000 different DMNs in order to investigate the underlying mechanism of this dynamic global configuration. The numerical analyses that we have performed show that this global configuration is an emergent property inherent to the cellular metabolic dynamics. Concretely, we have found that the existence of a high number of enzymatic subsystems belonging to the DMNs is the fundamental element for the spontaneous emergence of a functional reactive structure characterized by a metabolic core formed by several sets of enzymes always in an active state. Conclusions/Significance: This self-organized dynamic structure seems to be an intrinsic characteristic of metabolism, common to all living cellular organisms. To better understand cellular functionality, it will be crucial to structurally characterize these enzymatic self-organized global structures.