Space and Gender in the Ancient Greek Novel

The plots of the five Greek novels of "love and Adventures" are set in two differentent spaces. First, a macrospace, a gigantic stage which mainly includes Eastern cities of the Roman Empire, where the protagonists live the so-called adventures. And second, the microspaces, depicted in Longus' novel and occasionally in the other novels. The love ideology is clearly conservative, and it has a specific practical purpose among the Hellenized higher classes in the Eastern Empire.

Un episodio de “estilización” de la política antirrepublicana: la fiesta de San Francisco Javier de 1931 en Pamplona

[ES] Estudio de caso (Fiesta de S. Francisco en Pamplona, Navarra) del modo en que la derecha conservadora española (Bloque de Derechas) y los radicales (carlistas) emplearon densos elementos identificadores (“identidad”) de lo local (Navarra-España) y católica para generar actitudes y adhesiones políticas antirrepublicanas.

El clasicismo en el País Vasco: Ramón de Basterra

[ES] Este trabajo analiza la obra del poeta y ensayista Ramón de Basterra (1888-1928), tratando de establecer las peculiaridades de su dimensión clasicista, en comparación con las líneas generales del clasicismo de la época. El clasicismo es visto como un componente fundamental de las ideologías conservadoras y del fascismo en el siglo XX. Se destacan las relaciones del autor con la intelectualidad vasca, especialmente bilbaína , y española. El conjunto de su obra, en particular La obra de Trajano (1921) y Las ubres luminosas (1923), representan una singular aportación a la historia del clasicismo, poco estudiado todavía en nuestro país. Para Basterra. La romanidad, la latinidad y la cristiandad como ejes de la misión civilizatoria de Occidente y su concepción esencialista y ahistórica de la raza y la nacionalidad españolas son elementos centrales de la obra basterriana. En la perspectiva de un análisis del fascismo que destaca el papel nuclear del culto a la romanidad, este autor podría ser definido como "protofascista".

Análisis del tratamiento del medio físico en el planeamiento territorial de la Comunidad Autómoma del País Vasco (1940-2006).

851 p. : il.

Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma

Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic traits. Several low penetrance susceptibility genes associated with malignant melanoma (MM) have been described, including genes related to pigmentation, DNA damage repair and oxidative stress pathways. In the present work, we conducted a candidate gene association study based on proteins and genes whose expression we had detected altered in melanoma cell lines as compared to normal melanocytes. The result was the selection of 88 loci and 384 SNPs, of which 314 fulfilled our quality criteria for a case-control association study. The SNP rs6854854 in ANXA5 was statistically significant after conservative Bonferroni correction when 464 melanoma patients and 400 controls were analyzed in a discovery Phase I. However, this finding could not be replicated in the validation phase, perhaps because the minor allele frequency of SNP rs6854854 varies depending on the geographical region considered. Additionally, a second SNP (rs6431588) located on ILKAP was found to be associated with melanoma after considering a combined set of 1,883 MM cases and 1,358 disease-free controls. The OR was 1.29 (95% CI 1.12-1.48; p-value= 4x10(-4)). Both SNPs, rs6854854 in ANXA5 and rs6431588 in ILKAP, show population structure, which, assuming that the Spanish population is not significantly structured, suggests a role of these loci on a specific genetic adaptation to different environmental conditions. Furthermore, the biological relevance of these genes in MM is supported by in vitro experiments, which show a decrease in the transcription levels of ANXA5 and ILKAP in melanoma cells compared to normal melanocytes.