Linking Reduced Deforestation and a Global Carbon Market: Impacts on Costs, Financial Flows, and Technological Innovation

25 p.

Guided pollards in the Basque Country (Spain) during the Early Modern Ages

Publicado en: "End of Tradition?.Part 1 : History of Commons and Commons Management (Cultural Severance and Commons Past)", edited by Ian D. Rotherham, Mauro Agnoletti and Christine Handley

Enirio-Aralar mendietako abereen eta basoen ustiapena aro berrian zehar

[EUS]Enirio-Aralarreko mendietako basoek ez dute XVIII. mendera arte ustiapen gogorrik jasango. Ordura arte Batasunetako biztanleek behar zuten egurra soilik ateratzen zuten, ia ustiapen industrialik gabe. XVIII. mendean, beheko aldeko hariztiak agortu zirenean, Enirio-Aralarreko pagoak hasi ziren ustiatzen ikatza, itsasontziak edo arma-kajoiak egiteko. Aldi berean, ordura arte “tokian tokiko” abeltzaintza izan zena, erdi trashumantzia bihurtu zen: kostaldeko eta inguruko artaldeak Enirio-Aralar mendietan hasi ziren uda ematen. Aipatutako bi faktoreek –basoaren ustiapenak eta kanpoko artaldeen etorrerak–, batik bat XVIII. mendearen bukaeran eta XIX. mendearen hasieran, Enirio-Aralarreko basoaren atzerakada eragin zuten. XIX eta XX. mendeetan zehar deforestazioa areagotu egin zen, bertako mendiei gaur egun ezagutzen dugun itxura eman arte.

The Cancun Climate Summit: a Moderate Success

4 p.

Payments for Water Ecosystem Services in Latin America: Evidence from Reported Experience

27 p.

Paleoambiente y antropización en los Pirineos de Navarra durante el Holoceno medio (VI-IV PDF milenios cal. BC): Una perspectiva palinológica

Homenaje a Ignacio Barandiarán Maestu / coord. por Javier Fernández Eraso, Juan Santos Yanguas

Piper and Vismia Species from Colombian Amazonia Differentially Affect Cell Proliferation of Hepatocarcinoma Cells

There is an increasing interest to identify plant-derived natural products with antitumor activities. In this work, we have studied the effects of aqueous leaf extracts from Amazonian Vismia and Piper species on human hepatocarcinoma cell toxicity. Results showed that, depending on the cell type, the plants displayed differential effects; thus, Vismia baccifera induced the selective killing of HepG2, while increasing cell growth of PLC-PRF and SK-HEP-1. In contrast, these two last cell lines were sensitive to the toxicity by Piper krukoffii and Piper putumayoense, while the Piperaceae did not affect HepG2 growth. All the extracts induced cytotoxicity to rat hepatoma McA-RH7777, but were innocuous (V. baccifera at concentrations < 75 mu g/mL) or even protected cells from basal death (P. putumayoense) in primary cultures of rat hepatocytes. In every case, cytotoxicity was accompanied by an intracellular accumulation of reactive oxygen species (ROS). These results provide evidence for the anticancer activities of the studied plants on specific cell lines and suggest that cell killing could be mediated by ROS, thus involving mechanisms independent of the plants free radical scavenging activities. Results also support the use of these extracts of the Vismia and Piper genera with opposite effects as a model system to study the mechanisms of the antitumoral activity against different types of hepatocarcinoma.