Generación en aire del tercer armónico de pulsos de femtosegundos centrados en 800 nm

El trabajo llevado a cabo se enmarca en el campo de los pulsos de luz ultracortos, teniendo como objetivo la construcción de un sistema capaz de generar pulsos de femtosegundos con duraciones inferiores a 30 fs en la región del ultravioleta. Para poder obtenerlos, se ha puesto a punto un sistema óptico que partiendo de pulsos provenientes de una fuente comercial, con una duración aproximada de 50 fs y centrados en 800 nm, ha permitido producir pulsos a 267 nm con duraciones inferiores a 30 fs. Para ello se ha usado un proceso no lineal de generación de tercer armónico (TH), empleando como medio activo un filamento generado en aire libre y en un canal taladrado en una lámina delgada de acero. El trabajo realizado ha permitido dotar al laboratorio de una herramienta nueva para llevar a cabo experimentos de dínamica molecular.

High-Throughput Sequencing of microRNAs in Peripheral Blood Mononuclear Cells: Identification of Potential Weight Loss Biomarkers

INTRODUCTION: MicroRNAs (miRNAs) are being increasingly studied in relation to energy metabolism and body composition homeostasis. Indeed, the quantitative analysis of miRNAs expression in different adiposity conditions may contribute to understand the intimate mechanisms participating in body weight control and to find new biomarkers with diagnostic or prognostic value in obesity management. OBJECTIVE: The aim of this study was the search for miRNAs in blood cells whose expression could be used as prognostic biomarkers of weight loss. METHODS: Ten Caucasian obese women were selected among the participants in a weight-loss trial that consisted in following an energy-restricted treatment. Weight loss was considered unsuccessful when <5% of initial body weight (non-responders) and successful when >5% (responders). At baseline, total miRNA isolated from peripheral blood mononuclear cells (PBMC) was sequenced with SOLiD v4. The miRNA sequencing data were validated by RT-PCR. RESULTS: Differential baseline expression of several miRNAs was found between responders and non-responders. Two miRNAs were up-regulated in the non-responder group (mir-935 and mir-4772) and three others were down-regulated (mir-223, mir-224 and mir-376b). Both mir-935 and mir-4772 showed relevant associations with the magnitude of weight loss, although the expression of other transcripts (mir-874, mir-199b, mir-766, mir-589 and mir-148b) also correlated with weight loss. CONCLUSIONS: This research addresses the use of high-throughput sequencing technologies in the search for miRNA expression biomarkers in obesity, by determining the miRNA transcriptome of PBMC. Basal expression of different miRNAs, particularly mir-935 and mir-4772, could be prognostic biomarkers and may forecast the response to a hypocaloric diet.

Design and Development of a Low-Cost Optical Current Sensor

In this paper we demonstrate the design of a low-cost optical current sensor. The sensor principle is the Faraday rotation of a light beam through a magneto-optical material, SF2, when a magnetic field is present. The prototype has a high sensitivity and a high linearity for currents ranging from 0 up to 800 A. The error of the optical fibre sensor is smaller than 1% for electric currents over 175 A.

Jolas sakona: txapelketaren prozesu errituala eta bertsolariaren arrazoi sortzailea XXI mendeko agoran

455 p.

Breaking the 400 ppm barrier: Physical and Social implications of the recent CO2 rise

6 p.

Rompiendo la barrera de las 400 ppm: implicaciones físicas y sociales del reciente aumento de CO2

6 p.

400 ppm-ko langa hautsi da: CO2-kontzentrazioaren igoeraren ondorio fisiko eta sozialak

6 p.

La cerámica de la Segunda Edad del Hierro en el País Vasco: Estudio tecnológico, funcional y social

670 p. Capítulos de introducción, metodología, discusión y conclusiones en castellano e inglés.

Análisis de las interferencias de emisiones LTE sobre servicios DVB-T

[ES]Con la llegada de las tecnologías digitales y los nuevos sistemas de compresión, la misma información puede ser transmitida en menor espacio. Además, el uso de las tecnologías móviles está evolucionando considerablemente, aportando numerosos beneficios. Es esto lo que ha motivado la liberación del espectro radioeléctrico en la banda de 800 MHz para la convivencia del servicio de radiodifusión y el de comunicaciones móviles en bandas adyacentes. Mediante la realización de este proyecto se estudiará el comportamiento de ambos sistemas, para lo que se obtendrán valores de relaciones de protección y umbrales de sobrecarga.

We can work it out: an enactive look at cooperation

The past years have seen an increasing debate on cooperation and its unique human character. Philosophers and psychologists have proposed that cooperative activities are characterized by shared goals to which participants are committed through the ability to understand each other’s intentions. Despite its popularity, some serious issues arise with this approach to cooperation. First, one may challenge the assumption that high-level mental processes are necessary for engaging in acting cooperatively. If they are, then how do agents that do not possess such ability (preverbal children, or children with autism who are often claimed to be mind-blind) engage in cooperative exchanges, as the evidence suggests? Secondly, to define cooperation as the result of two de-contextualized minds reading each other’s intentions may fail to fully acknowledge the complexity of situated, interactional dynamics and the interplay of variables such as the participants’ relational and personal history and experience. In this paper we challenge such accounts of cooperation, calling for an embodied approach that sees cooperation not only as an individual attitude toward the other, but also as a property of interaction processes. Taking an enactive perspective, we argue that cooperation is an intrinsic part of any interaction, and that there can be cooperative interaction before complex communicative abilities are achieved. The issue then is not whether one is able or not to read the other’s intentions, but what it takes to participate in joint action. From this basic account, it should be possible to build up more complex forms of cooperation as needed. Addressing the study of cooperation in these terms may enhance our understanding of human social development, and foster our knowledge of different ways of engaging with others, as in the case of autism.

Retórica y derecho en la Alta Edad Media: una defensa judicial del siglo IX

[ES] El objetivo de este artículo es Mostrar un aspecto particular de la Retórica en la Alta Edad Media, a saber, la vinculación de esta "Ars" con la práctica judicial y los estudios de Derecho. Para ello, hemoss analizado un documento relativamente "raro" en tanto que es casi el único de sus características en la Hispania del siglo IX: una defensa judicial incluída en el «Epistolario» de Álvaro de Córdoba (n.c. 800), uno de los mejores escritores en lengua latina de su época. La elección del citado documento tiene su razón de ser en la oscuridad e incertidumbre que rodean nuestro conocimiento de las fuentes y de los procedimientos jurídicos de dicha época.