106 resultados para Miranda Fricker


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[ES] El objetivo consiste en la obtención de un conjunto de planos (planta, alzados y perspectivas) del Ninfeo mediante la restitución de pares estereoscópicos del Ninfeo. De forma auxiliar se ha generado un programa de ordenador que permite calcular una transformación tridimensional de coordenadas.

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[EN] This paper is an outcome of the ERASMUS IP program called TOPCART, there are more information about this project that can be accessed from the following item:

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[ES] La documentación de este proyecto ha servido como base para la realización de los siguientes proyectos y artículos:

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[ES] Tumba megalítica compuesta por 8 losas (6 en la cámara, una de ellas caída originalmente y 2 en el corredor). El tamaño de la cámara es de unos 2 x 2,5 metros que se encuentra en un morcuero de unos 10 metros de diámetro.

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[ES] El edificio tiene planta rectangular de unos 30 x 15 metros con un interior con una altura de 10 metros. Cuenta con una torre anexa a los pies y un pórtico de piedra de ocho arcos de posible factura medieval. La antigua cabecera ha quedado como la sacristía actual.

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Background: Vitamin K has been related to glucose metabolism, insulin sensitivity and diabetes. Because inflammation underlies all these metabolic conditions, it is plausible that the potential role of vitamin K in glucose metabolism occurs through the modulation of cytokines and related molecules. The purpose of the study was to assess the associations between dietary intake of vitamin K and peripheral adipokines and other metabolic risk markers related to insulin resistance and type 2 diabetes mellitus. Methods: Cross-sectional and longitudinal assessments of these associations in 510 elderly participants recruited in the PREDIMED centers of Reus and Barcelona (Spain). We determined 1-year changes in dietary phylloquinone intake estimated by food frequency questionnaires, serum inflammatory cytokines and other metabolic risk markers. Results: In the cross-sectional analysis at baseline no significant associations were found between dietary phylloquinone intake and the rest of metabolic risk markers evaluated, with exception of a negative association with plasminogen activator inhibitor-1. After 1-year of follow-up, subjects in the upper tertile of changes in dietary phylloquinone intake showed a greater reduction in ghrelin (-15.0%), glucose-dependent insulinotropic peptide (-12.9%), glucagon-like peptide-1 (-17.6%), IL-6 (-27.9%), leptin (-10.3%), TNF (-26.9%) and visfatin (-24.9%) plasma concentrations than those in the lowest tertile (all p<0.05). Conclusion: These results show that dietary phylloquinone intake is associated with an improvement of cytokines and other markers related to insulin resistance and diabetes, thus extending the potential protection by dietary phylloquinone on chronic inflammatory diseases.

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Background: A remarkable range of biological functions have been ascribed to resveratrol. Recently, this polyphenol has been shown to have body fat lowering effects. The aim of the present study was to assess some of the potential underlying mechanisms of action which take place in adipose tissue. Methods: Sixteen male Sprague-Dawley rats were randomly divided into two groups: control and treated with 30 mg resveratrol/kg body weight/d. All rats were fed an obesogenic diet and after six weeks of treatment white adipose tissues were dissected. Lipoprotein lipase activity was assessed by fluorimetry, acetyl-CoA carboxylase by radiometry, and malic enzyme, glucose-6P-dehydrogenase and fatty acid synthase by spectrophotometry. Gene expression levels of acetyl-CoA carboxylase, fatty acid synthase, lipoprotein lipase, hormone-sensitive lipase, adipose triglyceride lipase, PPAR-gamma, SREBP-1c and perilipin were assessed by Real time RT-PCR. The amount of resveratrol metabolites in adipose tissue was measured by chromatography. Results: There was no difference in the final body weight of the rats; however, adipose tissues were significantly decreased in the resveratrol-treated group. Resveratrol reduced the activity of lipogenic enzymes, as well as that of heparin-releasable lipoprotein lipase. Moreover, a significant reduction was induced by this polyphenol in hormone-sensitive lipase mRNA levels. No significant changes were observed in other genes. Total amount of resveratrol metabolites in adipose tissue was 2.66 +/- 0.55 nmol/g tissue. Conclusions: It can be proposed that the body fat-lowering effect of resveratrol is mediated, at least in part, by a reduction in fatty acid uptake from circulating triacylglycerols and also in de novo lipogenesis.

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209 p. : il., gráf.

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[ES] Este proyecto corresponde a una actualización del siguiente proyecto fin de carrera:

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[ES] La parte práctica de esta tesis se centra en un proyecto ERASMUS realizado en el Monasterio de San Prudencio de Monte Laturce (Clavijo, La Rioja). Dicho proyecto aparece descrito en varios registros de este mismo repositorio a los que se puede acceder a través del siguiente:

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[ES] Este proyecto tuvo una continuación en 2008, cuando se documentó la muralla interior del castillo. Este trabajo también está disponible en este repositorio. Asimismo, algunos artículos y proyectos fin de carrera hacen referencia a los datos capturados en este proyecto. En concreto, los registros relacionados son los siguientes:

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[ES] Este proyecto genera productos adicionales de trabajos también disponibles en el repositori, en concreto:

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[ES] Los resultados obtenidos en este proyecto están basados en otro anterior (2005) que también puede ser consultado en este repositorio: