Goierriko garraioaren hobekuntza eta ingurumen inpaktua

[EU]Goierriko eskualdean egun batean burutzen diren bidai guztien %9a bakarrik burutzen da garraio publiko bidez. Hau gertatzearen bizilagunen “aitzakia” nagusia honakoa da: zerbitzua oso txarra da. Niri ordea, ondorengo zalantza datorkit burura: nahiz eta zerbitzua hobea izan, garraio publikoa gehiago erabiliko litzateke? Hau biraka dabilen gurpil zoroa da. Zerbitzua txarra delako ez dabil jende gehiago, baina ez du merezi zerbitzua hobetzea jende gutxi ibiltzen delako. Guzti hau argitzearren eta Goierriko garraio publikoaren hobekuntza sustatzeko zer egin daitekeen aztertzeko garatu da lan hau. Hobekuntza termino hau autobus gehiago jartzearekin erlazionatzen dugu gehienetan, baina nik beste planteamendu bat eman nahi izan diot. Bidaiari gutxi daudenez, ezin dira maiztasun handiz autobusak ezarri, proiektua ez baita bideragarria. Horregatik dagoen zerbitzua, gutxi bada ere, bizilagunei erabat moldatua egotea mahaigaineratu nahi izan dut, bizilagun hauen sentsibilizazioari arreta berezia eskainiz.

Encuesta a la población andina en la Comunidad Autónoma del País Vasco (EPAPV, 2012). Dinámicas migratorias transnacionales de la población de Colombia, Ecuador y Perú

Encuesta realizada en el marco del proyecto “Implicaciones sociales de las migraciones transnacionales: más allá de las remesas. El caso del sistema migratorio entre países andinos y España”, con referencia CSO2009-08469 (subprograma SOCI). Este proyecto ha sido financiado por el Plan Nacional de I D i (2009-2012) del Ministerio de Ciencia e Innovación en su convocatoria de ayudas de Proyectos de Investigación Fundamental no orientada.

Measuring the influence of customer-based store brand equity in the purchase intention

[EN] Store brands account for and important market share in the Spain and a further increase in expected in the next years due to the downturn. However, there is lack of research on store brand customer-based Brand Equity. This study attempts to propose an integrated model of Brand Equity in store or retailer brands, based on Aaker s well-known conceptual model. We propose a consumer-based model, including the main sources or dimensions of Brand Equity and considering the intention to purchase as a consequence. Based on a sample of 362 consumers and 5 store brands, structural equation modeling is used to test research hypotheses. The results obtained reveal that store brand awareness, loyalty along with store brand perceived quality have a significant influence on consumers intention to purchase store brands. Our study suggests that marketers and marketing managers from retailing companies should carefully consider the Brand Equity components when designing their brand strategies, and develop marketing activities in order to enhance their brands awareness.

6th European Conference on Energy Efficiency and Sustainability in Architecture and Planning

[ES]Esta obra recoge las comunicaciones seleccionadas para el 6º Congreso Europeo sobre Eficiencia Energética y Sostenibilidad en Arquitectura, organizado por el grupo de investigación Calidad de Vida en Arquitectura de la Universidad del País Vasco/Euskal Herriko Unibertsitatea. El congreso, que se celebra en el marco de los XXXIV Cursos de Verano de la UPV/EHU, aborda en esta cuarta edición el tema “Ciudades en riesgo: resiliencia y redundancia”. Alrededor de este tema general se desarrollan cinco ponencias magistrales, a cargo de Margaretha Breil (Centro Euro-Mediterráneo para el Cambio Climático), Cristina Garzillo Leemhuis (ICLEI), Ignasi Fontanals (OptiCits), Juan Carlos Barrios Montenegro (Global Action Plan) y Manuel Valdés López (Ajuntament de Barcelona). Además, 24 comunicaciones seleccionadas por el comité científico presentarán trabajos de investigaciones actuales en las sesiones orales y póster. Es objetivo paralelo del congreso es fortalecer las líneas de investigación en eficiencia energética y sostenibilidad de los grupos de investigación y formación de la UPV/ EHU comprometidos con esta propuesta, con objeto de colaborar en el reforzamiento de la I D i en su ámbito de conocimiento y apoyar la apuesta específica de los Gobiernos Central y Vasco, así como de otras instituciones nacionales e internacionales respecto a las actividades de I D i en las materias relacionadas con el cambio climático, la eficiencia energética y la sostenibilidad ambiental [ENG] This work contains the selected abstracts of the 6th European Conference on Energy Efficiency and Sustainability in Architecture and Planning, organized by the research group Quality of life in Architecture of the University of the Basque Country. The conference is part of the XXXIV Summer Courses of the UPV/EHU and deals, in its fourth edition, with the topic “Cities at risk: resilience and redundancy”. Around this general theme there are five invited speakers: Margaretha Breil (Euro-Mediterranean Centre for Climate Change), Cristina Garzillo Leemhuis (ICLEI), Ignasi Fontanals (OptiCits), Juan Carlos Barrios Montenegro (Global Action Plan) y Manuel Valdés López (Barcelona City Council). 24 abstracts additional have been selected by the scientific committee that offer actual research works in presentations and posters. The purpose of the conferences is to strengthen the investigation lines in energy efficiency and sustainability of the research and education groups of the University of the Basque Country (UPV/EHU) involved, with the purpose of collaborating in the reinforcement of the I D i in its field of knowledge, and support the specific projects of the Central and Basque Governments, as well as other national and international institutions related to the I Di activities in similar fields of climate change, energy efficiency and environmental sustainability.

Política y medios de comunicación: reflexiones poliédricas sobre una relación compleja

Índice: - Introducción (Miguel Ángel Casado y Jone Martínez). - Presentación del libro-CD Elecciones vascas 2009 (José Ignacio Armentia). - Elecciones vascas 2009. Siete diarios, tres candidatos y un diálogo (Iker Merodio). - Medios y política desde la Academia (José V. Idoyaga). - Comunicación y poder (Pedro Ibarra). - Apuntes desconcertados de un universitario de larga relación con los medios ahora metido a político (Imanol Zubero). - Las televisiones, al servicio de la campaña electoral (Marian González). - Cuando la política se estrecha, los políticos son el problema. Un apunte sobre prensa y política (Xabier Aierdi). - La comunicación en tus manos (Paul Ríos). - Política digital en 2010 (Mikel Agirregabiria). - Komunikabideak eta politika, AHT kasua aztergai: abiadura handiko informazioa, trena norantz doa? AHT eta prensa Euskal Herrian (Iñaki Barcena). - Komunikabideak eta politika. Zientzia politikotik ikuspegi bat: informazioaren mozorroa aztergai (Izaro Gorostidi). - Movimientos sociales y medios de comunicación: el caso de las movilizaciones anti- Bolonia (Joseba Fernández). - La autodeterminación como solución política a una Transición democrática mal resuelta (Cristina Perales). - Políticos y periodistas: reflexiones para un debate inacabado (Txema Ramírez de la Piscina). - Políticos y periodistas (Sonia Hernando). - Políticos vs. periodistas (Josu Segovia). - Periodismo y política (Pedro García). - La prensa y los círculos de poder. La prensa en los círculos de poder (Aratzazu Zugasti). - Medios de comunicación y discursos políticos. El reto de asumir responsabilidades sociales (Soraia Chacón). - Elecciones vascas 2009. Política y comunicación (Andoni Ortuzar). Información 2.0, ¿quiénes ejercen hoy la influencia? ¿Es el fin de la agenda setting? (Alain Coloma). - XXI. mendeko laugarren boterea: gizartea (Ugaitz Zabala). - Política y medios de comunicación: una relación de amor-odio permanente (Oskar Matute).

Fast and Efficient Neural Conversion of Human Hematopoietic Cells

Neurons obtained directly from human somatic cells hold great promise for disease modeling and drug screening. Available protocols rely on overexpression of transcription factors using integrative vectors and are often slow, complex, and inefficient. We report a fast and efficient approach for generating induced neural cells (iNCs) directly from human hematopoietic cells using Sendai virus. Upon SOX2 and c-MYC expression, CD133-positive cord blood cells rapidly adopt a neuroepithelial morphology and exhibit high expansion capacity. Under defined neurogenic culture conditions, they express mature neuronal markers and fire spontaneous action potentials that can be modulated with neurotransmitters. SOX2 and c-MYC are also sufficient to convert peripheral blood mononuclear cells into iNCs. However, the conversion process is less efficient and resulting iNCs have limited expansion capacity and electrophysiological activity upon differentiation. Our study demonstrates rapid and efficient generation of iNCs from hematopoietic cells while underscoring the impact of target cells on conversion efficiency.

The role of syllables in sign language production

The aim of the present study was to investigate the functional role of syllables in sign language and how the different phonological combinations influence sign production. Moreover, the influence of age of acquisition was evaluated. Deaf signers (native and non-native) of Catalan Signed Language (LSC) were asked in a picture-sign interference task to sign picture names while ignoring distractor-signs with which they shared two phonological parameters (out of three of the main sign parameters: Location, Movement, and Handshape). The results revealed a different impact of the three phonological combinations. While no effect was observed for the phonological combination Handshape-Location, the combination Handshape-Movement slowed down signing latencies, but only in the non-native group. A facilitatory effect was observed for both groups when pictures and distractors shared Location-Movement. Importantly, linguistic models have considered this phonological combination to be a privileged unit in the composition of signs, as syllables are in spoken languages. Thus, our results support the functional role of syllable units during phonological articulation in sign language production.

Acciones socio educativas de las Orquestas Sinfónicas Españolas y de Gran Bretaña

327 p. + anexos

Mugilid Fish Are Sentinels of Exposure to Endocrine Disrupting Compounds in Coastal and Estuarine Environments

Effects on fish reproduction can result from a variety of toxicity mechanisms first operating at the molecular level. Notably, the presence in the environment of some compounds termed endocrine disrupting chemicals (EDCs) can cause adverse effects on reproduction by interfering with the endocrine system. In some cases, exposure to EDCs leads to the animal feminization and male fish may develop oocytes in testis (intersex condition). Mugilid fish are well suited sentinel organisms to study the effects of reproductive EDCs in the monitoring of estuarine/marine environments. Up-regulation of aromatases and vitellogenins in males and juveniles and the presence of intersex individuals have been described in a wide array of mullet species worldwide. There is a need to develop new molecular markers to identify early feminization responses and intersex condition in fish populations, studying mechanisms that regulate gonad differentiation under exposure to xenoestrogens. Interestingly, an electrophoresis of gonad RNA, shows a strong expression of 5S rRNA in oocytes, indicating the potential of 5S rRNA and its regulating proteins to become useful molecular makers of oocyte presence in testis. Therefore, the use of these oocyte markers to sex and identify intersex mullets could constitute powerful molecular biomarkers to assess xenoestrogenicity in field conditions.

Estudio del proceso de valorización energética de los residuos sólidos urbanos en una planta de incineración.

[ES]El objetivo de este Trabajo Fin de Grado consiste en estudiar el proceso desarrollado en la planta de incineración de residuos sólidos urbanos de Zabalgarbi (Bizkaia). La planta consiste en un ciclo combinado basado en una turbina de gas de 43 MW y una turbina de vapor de 56,5 MW. La importancia de su diseño recae en la adaptación de la tecnología de ciclo combinado de gas a la tecnología propia de una planta de valorización energética de residuos municipales. Es decir, se trata de un diseño innovador, del que surge un nuevo proceso industrial que permite dar solución a la problemática generada por los residuos producidos a la vez que se genera energía eléctrica. Gracias a este diseño, se consigue una mejora cualitativa y cuantitativa del rendimiento de la planta, ya que se obtiene energía eléctrica en dos etapas, además de un mejor aprovechamiento de los recursos. La tecnología utilizada para la incineración es el horno-caldera de parrilla deslizante. En este trabajo se analizarán los procesos integrados en la planta y se realizará el estudio energético de los equipos más significativos. Una vez realizada esta parte, se considerarán ciertas mejoras a incorporar en la instalación. Además, se desarrollará la metodología seguida para la realización del estudio así como la planificación y el presupuesto.

Identidad digital y reputación on-line

La identidad digital y la reputación online como elementos claves a la hora de relacionarse con el consumidor y generar valor

Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma

Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic traits. Several low penetrance susceptibility genes associated with malignant melanoma (MM) have been described, including genes related to pigmentation, DNA damage repair and oxidative stress pathways. In the present work, we conducted a candidate gene association study based on proteins and genes whose expression we had detected altered in melanoma cell lines as compared to normal melanocytes. The result was the selection of 88 loci and 384 SNPs, of which 314 fulfilled our quality criteria for a case-control association study. The SNP rs6854854 in ANXA5 was statistically significant after conservative Bonferroni correction when 464 melanoma patients and 400 controls were analyzed in a discovery Phase I. However, this finding could not be replicated in the validation phase, perhaps because the minor allele frequency of SNP rs6854854 varies depending on the geographical region considered. Additionally, a second SNP (rs6431588) located on ILKAP was found to be associated with melanoma after considering a combined set of 1,883 MM cases and 1,358 disease-free controls. The OR was 1.29 (95% CI 1.12-1.48; p-value= 4x10(-4)). Both SNPs, rs6854854 in ANXA5 and rs6431588 in ILKAP, show population structure, which, assuming that the Spanish population is not significantly structured, suggests a role of these loci on a specific genetic adaptation to different environmental conditions. Furthermore, the biological relevance of these genes in MM is supported by in vitro experiments, which show a decrease in the transcription levels of ANXA5 and ILKAP in melanoma cells compared to normal melanocytes.

La migración transnacional y los procesos de integración en las sociedades de destino. Una mirada a la población colombiana residente en la Comunidad Autónoma del País Vasco

411 p.

Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease

The neurotransmitter serotonin (5-HT) has a multifaceted function in the modulation of information processing through the activation of multiple receptor families, including G-protein-coupled receptor subtypes (5-HT1, 5-HT2, 5-HT4-7) and ligand-gated ion channels (5-HT3). The largest population of serotonergic neurons is located in the midbrain, specifically in the raphe nuclei. Although the medial and dorsal raphe nucleus (DRN) share common projecting areas, in the basal ganglia (BG) nuclei serotonergic innervations come mainly from the DRN. The BG are a highly organized network of subcortical nuclei composed of the striatum (caudate and putamen), subthalamic nucleus (STN), internal and external globus pallidus (or entopeduncular nucleus in rodents, GPi/EP and GPe) and substantia nigra (pars compacta, SNc, and pars reticulata, SNr). The BG are part of the cortico-BG-thalamic circuits, which play a role in many functions like motor control, emotion, and cognition and are critically involved in diseases such as Parkinson's disease (PD). This review provides an overview of serotonergic modulation of the BG at the functional level and a discussion of how this interaction may be relevant to treating PD and the motor complications induced by chronic treatment with L-DOPA.

Soluciones pragmáticas en el campo privado para la cobertura de dependencia en España

336 p.