The acquisition of Tense and Aspect in Spanish

280 p.

El desafío de exponer: procesos y retos museográficos

Il y a aussi des chapitres en français. There are also chapters in English. Cap. 1. El complicado arte de exponer. Iñaki Arrieta Urtizberea. Cap. 2. “Esta exposición no es para este museo”. Las salas permanentes del Museu Valencià d’Etnologia. Joan Segui. Cap. 3. Debunking, Decentralizing and Dissonance: Cultural Jamming @ Museum of Vancouver. Viviane Gosselin. Cap. 4. L’exposition des objets de cultures autochtones aujourd’hui, gain ou perte de sens? Le cas de l’exposition « C’est notre histoire... » au Musée de la civilisation de Québec. Daniel Arsenault et Nadine Desbiens. Cap. 5. El Born de Barcelona: exposiciones conmemorativas, límites, problemas y desafíos. Francesc Xavier Hernàndez Cardona. Cap. 6. Silencios y omisiones: narrando y exhibiendo la historia nacional. Magdalena Mieri. Cap. 7. Exhibiting the Commons. The Case of Tensta konsthall. Haizea Barcenilla Garcia. Cap. 8. Interactividad y patrimonio. Retos, tendencias y líneas de futuro. Núria Serrat Antolí.

Localización por imagen de alta resolución del sistema cannabinoide endógeno en la mitocondria del músculo estriado de roedor

96 p.

Inferencia estadística: estimación por intervalo de confianza y contraste de independencia

Nivel educativo: Grado. Duración (en horas): De 31 a 40 horas

Cómo regulan las células su actividad para responder a las necesidades de nuestro cuerpo?

Nivel educativo: Grado. Duración (en horas): De 21 a 30 horas

Muscle wasting in myotonic dystrophies: a model of premature aging

Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem disorders of genetic origin. Progressive muscular weakness, atrophy and myotonia are the most prominent neuromuscular features of these diseases, while other clinical manifestations such as cardiomyopathy, insulin resistance and cataracts are also common. From a clinical perspective, most DM symptoms are interpreted as a result of an accelerated aging (cataracts, muscular weakness and atrophy, cognitive decline, metabolic dysfunction, etc.), including an increased risk of developing tumors. From this point of view, DM1 could be described as a progeroid syndrome since a notable age dependent dysfunction of all systems occurs. The underlying molecular disorder in DM1 consists of the existence of a pathological (CTG) triplet expansion in the 3' untranslated region (UTR) of the Dystrophia ll/Iyotonica Protein Kinase (DMPK) gene, whereas (CCTG)n repeats in the first intron of the Cellular Nucleic acid Binding Protein/Zinc Finger Protein 9 (CNBP/ZNF9) gene cause DM2. The expansions are transcribed into (CUG)n and (CCUG)n-containing RNA, respectively, which form secondary structures and sequester RNA binding proteins, such as the splicing factor muscleblind-like protein (MBNL), forming nuclear aggregates known as foci. Other splicing factors, such as CUGBP, are also disrupted, leading to a spliceopathy of a large number of downstream genes linked to the clinical features of these diseases. Skeletal muscle regeneration relies on muscle progenitor cells, known as satellite cells, which are activated after muscle damage, and which proliferate and differentiate to muscle cells, thus regenerating the damaged tissue. Satellite cell dysfunction seems to be a common feature of both age-dependent muscle degeneration (sarcopenia) and muscle wasting in DM and other muscle degenerative diseases. This review aims to describe the cellular, molecular and macrostructural processes involved in the muscular degeneration seen in DM patients, highlighting the similarities found with muscle aging.

Hidrogenoaren ekoizpena biomasaren pirolisia eta erreformatzearen bidez: operazio baldintzen optimizazioa

Gradu Amaierako Lan honekin hidrogenoaren ekoizpena ikertu nahi da, biomasaren pirolisi eta jarraian buruturiko lurrun bidezko hegazkorren erreformatze bidez. Helburu nagusia biomasaren pirolisiko produktuen erreformatzearen operazio baldintzak optimizatzea da nikelezko katalizatzaile komertzial bat erabiliz, eta horretarako: Tenperaturak erreformatuko produktuetan duen eragina aztertzea; Erreformatze etaparako denbora espazial optimoa zein den aztertzea; eta Ur/biomasa erlazioak erreformatuko produktuetan duen eragina aztertzea.

Seroprevalence of Triatoma virus (Dicistroviridae: Cripaviridae) antibodies in Chagas disease patients

Background: Chagas disease is caused by Trypanosoma cruzi, and humans acquire the parasite by exposure to contaminated feces from hematophagous insect vectors known as triatomines. Triatoma virus (TrV) is the sole viral pathogen of triatomines, and is transmitted among insects through the fecal-oral route and, as it happens with T. cruzi, the infected insects release the virus when defecating during or after blood uptake. Methods: In this work, we analysed the occurrence of anti-TrV antibodies in human sera from Chagas disease endemic and non-endemic countries, and developed a mathematical model to estimate the transmission probability of TrV from insects to man, which ranged between 0.00053 and 0.0015. Results: Our results confirm that people with Chagas disease living in Bolivia, Argentina and Mexico have been exposed to TrV, and that TrV is unable to replicate in human hosts. Conclusions: We presented the first experimental evidence of antibodies against TrV structural proteins in human sera.

Impact of Cyberprogram 2.0 on Different Types of School Violence and Aggressiveness

Some antibullying interventions have shown positive outcomes with regard to reducing violence. The aim of the study was to experimentally assess the effects on school violence and aggressiveness of a program to prevent and reduce cyberbullying. The sample was comprised of a randomly selected sample of 176 adolescents (93 experimental, 83 control), aged 13-15 years. The study used a repeated measures pre-posttest design with a control group. Before and after the program, two assessment instruments were administered: the "Cuestionario de Violencia Escolar-Revisado" (CUVE-R [School Violence Questionnaire- Revised]; Alvarez Garcia et al., 2011) and the "Cuestionario de agresividad premeditada e impulsiva" (CAPI-A [Premeditated and Impulsive Aggressiveness Questionnaire]; Andreu, 2010). The intervention consisted of 19 one-hour sessions carried out during the school term. The program contains 25 activities with the following objectives: (1) to identify and conceptualize bullying/cyberbullying; (2) to analyze the consequences of bullying/cyberbullying, promoting participants' capacity to report such actions when they are discovered; (3) to develop coping strategies to prevent and reduce bullying/cyberbullying; and (4) to achieve other transversal goals, such as developing positive variables (empathy, active listening, social skills, constructive conflict resolution, etc.). The pre-posttest ANCOVAs confirmed that the program stimulated a decrease in: (1) diverse types of school violence teachers' violence toward students (ridiculing or publicly humiliating students in front of the class, etc.); students' physical violence (fights, blows, shoves... aimed at the victim, or at his or her property, etc.); students' verbal violence (using offensive language, cruel, embarrassing, or insulting words... toward classmates and teachers); social exclusion (rejection or exclusion of a person or group, etc.), and violence through Information and Communication Technologies (ICT; violent behaviors by means of electronic instruments such as mobile phones and the Internet); and (2) premeditated and impulsive aggressiveness. Pre-posttest MANCOVA revealed differences between conditions with a medium effect size. This work contributes an efficacious intervention tool for the prevention and reduction of peer violence. The conclusions drawn from this study have interesting implications for educational and clinical intervention.