Revisión sistemática y metanálisis multivariado de la eficacia de potenciadores cognitivos en esquizofrenia

[287]p.

Cerámica cardial en la Rioja Alavesa

[ES] Se trata de dar a conocer el descubrimiento de cerámica impresa de tipo cardial en la Rioja Alavesa. Tales hallazgos se han localizado durante las excavaciones que se están realizando en el Abrigo de Peña Larga en Cripán (Alava) desde el verano de 1985. Las fechas obtenidas para el nivel de donde proceden las referidas cerámicas son: -5830 BC (para la parte superior del nivel). -6150 BC (para la parte baja en la que se encuentran las citadas cerámicas). Esta cronología sitúa el nivel en un Neolítico pleno en consonancia con los niveles cardiales localizados en las últimas décadas en el valle del Ebro.

Caracterización Molecular Y Epidemiológica de Cepas Monofásicas de Salmonella Enterica

225 p.

Estrategias para una VENTANA eficaz: Forma geométrica del HUECO - Diseño de la VENTANA-UH

V.1. 219 p.; V. 2. 589 p.

Salmonella enterica-ren andui monofasikoen karakterizazio molekularra eta epidemiologikoa

219 p.

Determinación de compuestos orgánicos potencialmente alérgenos en equipos textiles de protección individual (EPIs) mediante analisis directo por pirólisis acoplado a cromatografía de gases espectrometría de masas (Py-GC/MS).

Nota de aplicación instrumental desarrollada en el Servicio Central de Análisis de Bizkaia (SCAB)

Oteiza y Malévich. El proyecto de cementerio Izarrak Alde (del lado de las estrellas) para Ametzagaña

539 p.; 261 p.(anexos)

Haur eta gazte literatura eta ikus-entzunezko diskurtsoak: Momo eleberriaren marrazki-bizidunetako moldaketaz

[eus] Azken urteetako teknologia berrien iraultza dela eta, haur eta gazte literaturak bere forma aldatu du, ikus-entzunezko euskarrietara moldatuz, hartzaile haurrei erakargarriago eta ulergarriago suertatzearren. Adibide moduan Momo eleberria hartuta, bere moldaketa zinematografikorako erabili diren estrategiak aztertu dira eta bi adierazpen-euskarrien tramak konparatu dira. Analisi honen bidez frogatu ahal izan da moldaketa mota hauek, hain zuzen, jatorrizko lanaren sinplifikazioa inplikatzen dutela; hala ere, ez da arrazoi nahikoa hauek alde batera uzteko edo mesprezatzeko eta hezkuntza-baliabide posible gisa baztertzeko.

Electrónica de Potencia

Nivel educativo: Grado. Duración (en horas): Más de 50 horas

Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results

Based on numerous pharmacological studies that have revealed an interaction between cannabinoid and opioid systems at the molecular, neurochemical, and behavioral levels, a new series of hybrid molecules has been prepared by coupling the molecular features of two well-known drugs, ie, rimonabant and fentanyl. The new compounds have been tested for their affinity and functionality regarding CB1 and CB2 cannabinoid and mu opioid receptors. In [S-35]-GTP.S (guanosine 5'-O-[gamma-thio] triphosphate) binding assays from the post-mortem human frontal cortex, they proved to be CB1 cannabinoid antagonists and mu opioid antagonists. Interestingly, in vivo, the new compounds exhibited a significant dual antagonist action on the endocannabinoid and opioid systems.

Novel Papillomaviruses in Free-Ranging Iberian Bats: No Virus-Host Co-evolution, No Strict Host Specificity, and Hints for Recombination

Papillomaviruses (PVs) are widespread pathogens. However, the extent of PV infections in bats remains largely unknown. This work represents the first comprehensive study of PVs in Iberian bats. We identified four novel PVs in the mucosa of free-ranging Eptesicus serotinus (EserPV1, EserPV2, and EserPV3) and Rhinolophus ferrumequinum (RferPV1) individuals and analyzed their phylogenetic relationships within the viral family. We further assessed their prevalence in different populations of E. serotinus and its close relative E. isabellinus. Although it is frequent to read that PVs co-evolve with their host, that PVs are highly species-specific, and that PVs do not usually recombine, our results suggest otherwise. First, strict virus-host co-evolution is rejected by the existence of five, distantly related bat PV lineages and by the lack of congruence between bats and bat PVs phylogenies. Second, the ability of EserPV2 and EserPV3 to infect two different bat species (E. serotinus and E. isabellinus) argues against strict host specificity. Finally, the description of a second noncoding region in the RferPV1 genome reinforces the view of an increased susceptibility to recombination in the E2-L2 genomic region. These findings prompt the question of whether the prevailing paradigms regarding PVs evolution should be reconsidered.

Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?

Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids (omega-3) supplements in AMD prevention. Materials and Methods. Current knowledge on the cellular/molecular mechanisms of AMD and the epidemiologic/experimental studies on the effects of AOX and omega-3 were addressed all together with the scientific evidence and the personal opinion of professionals involved in the Retina Group of the OFTARED (Spain). Results. High dietary intakes of omega-3 and macular pigments lutein/zeaxanthin are associated with lower risk of prevalence and incidence in AMD. The Age-Related Eye Disease study (AREDS) showed a beneficial effect of high doses of vitamins C, E, beta-carotene, and zinc/copper in reducing the rate of progression to advanced AMD in patients with intermediate AMD or with one-sided late AMD. The AREDS-2 study has shown that lutein and zeaxanthin may substitute beta-carotene because of its potential relationship with increased lung cancer incidence. Conclusion. Research has proved that elder people with poor diets, especially with low AOX and omega-3 micronutrients intake and subsequently having low plasmatic levels, are more prone to developing AMD. Micronutrient supplementation enhances antioxidant defense and healthy eyes and might prevent/retard/modify AMD.

El conflicto palestino-israelí. ¿El Muro de Cisjordania como instrumento de limpieza étnica en Palestina? Un acercamiento a la realidad del muro.

Un acercamiento sucinto al conflicto palestino-israelí. Donde analizaremos el Muro de Cisjordania como instrumento de limpieza étnica.

Discurso de la prensa occidental en torno al Conflicto de Crimea

Análisis crítico del discurso empleado en los textos editoriales de la prensa generalista occidental en torno al Conflicto de Crimea.