The flow between rotating coaxial disks

Numerical approximations of nonunique solutions of the Navier-Stokes equations are obtained for steady viscous incompressible axisymmetric flow between two infinite rotating coaxial disks. For example, nineteen solutions have been found for the case when the disks are rotating with the same speed but in opposite direction. Bifurcation and perturbed bifurcation phenomena are observed. An efficient method is used to compute solution branches. The stability of solutions is analyzed. The rate of convergence of Newton's method at singular points is discussed. In particular, recovery of quadratic convergence at "normal limit points" and bifurcation points is indicated. Analytical construction of some of the computed solutions using singular perturbation techniques is discussed.

The Mechanical Genome in Regulation and Infection

Biological information storage and retrieval is a dynamic process that requires the genome to undergo dramatic structural rearrangements. Recent advances in single-molecule techniques have allowed precise quantification of the nano-mechanical properties of DNA [1, 2], and direct in vivo observation of molecules in action [3]. In this work, we will examine elasticity in protein-mediated DNA looping, whose structural rearrangement is essential for transcriptional regulation in both prokaryotes and eukaryotes. We will look at hydrodynamics in the process of viral DNA ejection, which mediates information transfer and exchange and has prominent implications in evolution. As in the case of Kepler's laws of planetary motion leading to Newton's gravitational theory, and the allometric scaling laws in biology revealing the organizing principles of complex networks [4], experimental data collapse in these biological phenomena has guided much of our studies and urged us to find the underlying physical principles.