1 resultado para New York Society for the Suppression of Vice.
em CaltechTHESIS
Filtro por publicador
- Aberdeen University (1)
- Aberystwyth University Repository - Reino Unido (2)
- Academic Archive On-line (Mid Sweden University; Sweden) (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (9)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (2)
- Aquatic Commons (2)
- Archive of European Integration (20)
- Aston University Research Archive (10)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (11)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (1)
- Biodiversity Heritage Library, United States (26)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (38)
- Boston University Digital Common (2)
- Brock University, Canada (14)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- CaltechTHESIS (1)
- Cambridge University Engineering Department Publications Database (5)
- CentAUR: Central Archive University of Reading - UK (17)
- Center for Jewish History Digital Collections (35)
- Central European University - Research Support Scheme (2)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (16)
- Cochin University of Science & Technology (CUSAT), India (2)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (1)
- CORA - Cork Open Research Archive - University College Cork - Ireland (3)
- CUNY Academic Works (2)
- Deakin Research Online - Australia (31)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Archives@Colby (2)
- Digital Commons - Michigan Tech (1)
- Digital Commons - Montana Tech (2)
- Digital Commons at Florida International University (1)
- Digital Peer Publishing (1)
- DigitalCommons@The Texas Medical Center (2)
- DigitalCommons@University of Nebraska - Lincoln (2)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (1)
- Greenwich Academic Literature Archive - UK (1)
- Harvard University (12)
- Helda - Digital Repository of University of Helsinki (5)
- Indian Institute of Science - Bangalore - Índia (11)
- INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES (IPEN) - Repositório Digital da Produção Técnico Científica - BibliotecaTerezine Arantes Ferra (1)
- Ministerio de Cultura, Spain (2)
- National Center for Biotechnology Information - NCBI (6)
- Nottingham eTheses (1)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (2)
- Portal de Revistas Científicas Complutenses - Espanha (1)
- Publishing Network for Geoscientific & Environmental Data (1)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (26)
- Queensland University of Technology - ePrints Archive (78)
- Repositório Científico da Universidade de Évora - Portugal (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (18)
- The Scholarly Commons | School of Hotel Administration; Cornell University Research (2)
- Universidad Autónoma de Nuevo León, Mexico (1)
- Universidad de Alicante (2)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (3)
- Universidade Complutense de Madrid (1)
- Universidade de Lisboa - Repositório Aberto (3)
- Universitat de Girona, Spain (1)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (1)
- Université de Lausanne, Switzerland (5)
- Université de Montréal, Canada (5)
- Université Laval Mémoires et thèses électroniques (1)
- University of Michigan (467)
- University of Queensland eSpace - Australia (14)
- USA Library of Congress (14)
- WestminsterResearch - UK (1)
Resumo:
Tryptophan and unnatural tryptophan derivatives are important building blocks for the total synthesis of natural products, as well as the development of new drugs, biological probes, and chiral small molecule catalysts. This thesis describes various catalytic methods for the preparation of tryptophan derivatives as well as their functionalization and use in natural product total synthesis.
Herein, the tandem Friedel–Crafts conjugate addition/asymmetric protonation reaction between 2-substituted indoles and methyl 2-acetamidoacrylate to provide enantioenriched trytophans is reported. This method inspired further work in the area of transition metal catalyzed arylation reactions. We report the development of the coppercatalyzed arylation of tryptamine and tryptophan derivatives. The utility of these transformations is highlighted in the five-step syntheses of the natural products (+)-naseseazine A and B. Further work on the development of a mild and general Larock indolization protocol to access unnatural tryptophans is also discussed.