Structural plasticity in MS channels
Contribuinte(s) |
Michelle Montoya |
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Data(s) |
01/01/2005
|
Resumo |
Gating of the mechanosensitive channel MscS involves cooperative action of glycine and alanine residues along the pore-lining transmembrane helix. Opening of the channel is facilitated by an iris-like rotation and tilt of the pore-lining helices. Site-directed mutagenesis indicates that substantial structural plasticity can be tolerated by MscS without impairing its function. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Nature Publishing Group |
Palavras-Chave | #Biochemistry & Molecular Biology #Biophysics #Cell Biology #Small Mechanosensitive Channel #Escherichia-coli Mscs #Gating Mechanism #Ion Channels #Cells #Dynamics #CX #279999 Biological Sciences not elsewhere classified #780105 Biological sciences |
Tipo |
Journal Article |