Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendocrine functions: A review


Autoria(s): Crestani, Carlos Cesar; Alves, Fernando H. F.; Gomes, Felipe V.; Resstel, Leonardo B. M.; Correa, Fernando M. A.; Herman, James P.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

27/05/2014

27/05/2014

30/04/2013

Resumo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Processo FAPESP: 10/16192-8

The bed nucleus of the stria terminalis (BNST) is a heterogeneous and complex limbic forebrain structure, which plays an important role in controlling autonomic, neuroendocrine and behavioral responses. The BNST is thought to serve as a key relay connecting limbic forebrain structures to hypothalamic and brainstem regions associated with autonomic and neuroendocrine functions. Its control of physiological and behavioral activity is mediated by local action of numerous neurotransmitters. In the present review we discuss the role of the BNST in control of both autonomic and neuroendocrine function. A description of BNST control of cardiovascular and hypothalamus-pituitary-adrenal axisactivity at rest and during physiological challenges (stress and physical exercise) is presented. Moreover, evidence for modulation of hypothalamic magnocellular neurons activity is also discussed. We attempt to focus on the discussion of BNST neurochemical mechanisms. Therefore, the source and targets of neurochemical inputs to BNST subregions and their role in control of autonomic and neuroendocrine function is discussed in details. © 2013 Bentham Science Publishers.

Formato

141-159

Identificador

http://dx.doi.org/10.2174/1570159X11311020002

Current Neuropharmacology, v. 11, n. 2, p. 141-159, 2013.

1570-159X

1875-6190

http://hdl.handle.net/11449/75192

10.2174/1570159X11311020002

WOS:000317845300002

2-s2.0-84876707420

Idioma(s)

eng

Relação

Current Neuropharmacology

Direitos

closedAccess

Palavras-Chave #BNST #Cardiovascular function #Extended amygdala #HPA axis #Neurotransmitters #Stress and physical exercise #Vasopressin #2 (2 methoxy 1, 4 benzodioxan 2 yl) 2 imidazoline #2 (2 methoxy 1,4 benzodioxan 2 yl) 2 imidazoline #2 [[2 (2, 6 dimethoxyphenoxy) ethyl] aminomethyl] 1, 4 benzodioxan #2 [[2 (2,6 dimethoxyphenoxy)ethyl]aminomethyl] 1,4 benzodioxan #4 aminobutyric acid #5 [2 [[2 hydroxy 3 [4 (1 methyl 4 trifluoromethyl 2 imidazolyl) phenoxy] propyl] amino] ethoxy] salicylamide #5 [2 [[2 hydroxy 3 [4 (1 methyl 4 trifluoromethyl 2 imidazolyl)phenoxy]propyl]amino]ethoxy]salicylamide #acetylcholine #bicuculline methiodide #cannabidiol #carbachol #cobalt chloride #corticotropin releasing factor #decahydro 6 phosphonomethyl 3 isoquinolinecarboxylic acid #glutamic acid #muscimol #neurotransmitter #nitric oxide #noradrenalin #oxytocin #unclassified drug #vasopressin #arterial pressure #autonomic nervous system #behavior #blood pressure #brain stem #chemoreceptor reflex #dynamic exercise #electrostimulation #exercise #fear #forebrain #human #hypothalamus #immobilization stress #magnocellular nucleus #microdialysis #nerve conduction #neuroendocrine system #neurotransmission #nonhuman #physiological process #pressoreceptor #review #stria terminalis
Tipo

info:eu-repo/semantics/review