Sulcus vocalis: evidence for autosomal dominant inheritance


Autoria(s): Martins, Regina Helena Garcia; Goncalves, T. M.; Neves, D. S.; Fracalossi, T. A.; Tavares, E. L. M.; Moretti-Ferreira, D.
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/01/2011

Resumo

We found evidence of autosomal dominant hereditary transmission of sulcus vocalis. Four dysphonic patients from three generations of the same family were submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy ( one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all four patients. The finding of four affected individuals in three generations, with vertical transmission affecting man and women, is more consistent with autosomal dominant inheritance pattern; it is an etiological model that we propose for the sulcus vocalis in this pedigree.

Formato

3163-3168

Identificador

http://dx.doi.org/10.4238/2011.December.19.5

Genetics and Molecular Research. Ribeirao Preto: Funpec-editora, v. 10, n. 4, p. 3163-3168, 2011.

1676-5680

http://hdl.handle.net/11449/12693

10.4238/2011.December.19.5

WOS:000300617600089

WOS000300617600089.pdf

Idioma(s)

eng

Publicador

Funpec-editora

Relação

Genetics and Molecular Research

Direitos

openAccess

Palavras-Chave #Autosomal dominant #Sulcus vocalis #Hoarseness #Videolaryngoscopy #Genetics #Laryngeal development
Tipo

info:eu-repo/semantics/article