Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation

Autoria(s): Yatmaz, S.; Seow, H.J.; Gualano, R.C.; Wong, Z.X.; Stambas, J.; Selemidis, S.; Crack, P.J.; Bozinovski, S.; Anderson, G.P.; Vlahos, R.
Data(s)

01/01/2013
Resumo

Oxidative stress caused by excessive reactive oxygen species production is implicated in influenza A virus–induced lung disease. Glutathione peroxidase (GPx)-1 is an antioxidant enzyme that may protect lungs from  such damage. The objective of this study was to determine if GPx-1 protects the lung against influenza A virus–induced lung inflammation in vivo.<br />
Identificador

http://hdl.handle.net/10536/DRO/DU:30053437
Idioma(s)

eng
Publicador

American Thoracic Society
Relação

http://dro.deakin.edu.au/eserv/DU:30053437/stambas-glutathioneperoxidase-2013.pdf

http://search.proquest.com/docview/1321675734/13F0DBD649B6E53261A/3?accountid=10445
Palavras-Chave #oxidative stress #reactive oxygen species #hydrogen peroxide #HKx31 #ebselen #antioxidants
Tipo

Journal Article
Acesso ao item digital