First dynamic kinetic resolution of selenium-containing chiral amines catalyzed by palladium (Pd/BaSO(4)) and Candida antartica lipase (CAL-B)
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
20/10/2012
20/10/2012
2009
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| Resumo |
An efficient method for chemoenzymatic dynamic kinetic resolution of selenium-containing chiral amines (organoselenium-1-phenylethanamines) has been developed, leading to the corresponding amides in excellent enantioselectivities and high isolated yields. This one-pot procedure employs two different types of catalysts: Pd on barium sulphate (Pd/BaSO(4)) as racemization catalyst and lipase (CAL-B) as the resolution catalyst. (C) 2009 Elsevier Ltd. All rights reserved. Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) CNPq Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) CAPES Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) FAPESP |
| Identificador |
TETRAHEDRON LETTERS, v.50, n.30, p.4331-4334, 2009 0040-4039 http://producao.usp.br/handle/BDPI/31171 10.1016/j.tetlet.2009.05.022 |
| Idioma(s) |
eng |
| Publicador |
PERGAMON-ELSEVIER SCIENCE LTD |
| Relação |
Tetrahedron Letters |
| Direitos |
closedAccess Copyright PERGAMON-ELSEVIER SCIENCE LTD |
| Palavras-Chave | #ASYMMETRIC-SYNTHESIS #ORGANOSELENIUM COMPOUNDS #RACEMIZATION #BIOCATALYSIS #EFFICIENT #ALCOHOLS #PD #Chemistry, Organic |
| Tipo |
article original article publishedVersion |
