The dynamics of cargo driven by molecular motors in the context of asymmetric simple exclusion processes
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
20/10/2012
20/10/2012
2009
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Resumo |
We consider the dynamics of cargo driven by a collection of interacting molecular motors in the context of ail asymmetric simple exclusion process (ASEP). The model is formulated to account for (i) excluded-volume interactions, (ii) the observed asymmetry of the stochastic movement of individual motors and (iii) interactions between motors and cargo. Items (i) and (ii) form the basis of ASEP models and have already been considered to study the behavior of motor density profile [A. Parmeggiani. T. Franosch, E. Frey, Phase Coexistence in driven one-dimensional transport, Phys. Rev. Lett. 90 (2003) 086601-1-086601-4]. Item (iii) is new. It is introduced here as an attempt to describe explicitly the dependence of cargo movement on the dynamics of motors in this context. The steady-state Solutions Of the model indicate that the system undergoes a phase transition of condensation type as the motor density varies. We study the consequences of this transition to the behavior of the average cargo velocity. (C) 2009 Elsevier B.V. All rights reserved. Funclacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) |
Identificador |
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS, v.388, n.17, p.3455-3464, 2009 0378-4371 http://producao.usp.br/handle/BDPI/29217 10.1016/j.physa.2009.04.038 |
Idioma(s) |
eng |
Publicador |
ELSEVIER SCIENCE BV |
Relação |
Physica A-statistical Mechanics and Its Applications |
Direitos |
restrictedAccess Copyright ELSEVIER SCIENCE BV |
Palavras-Chave | #Cargo transport #Molecular motors #Collective effects #ASEP #TRAFFIC FLOW #MYOSIN-V #TRANSPORT #KINESIN #MICROTUBULES #MODEL #COORDINATION #MOVEMENT #DYNACTIN #PROTEINS #Physics, Multidisciplinary |
Tipo |
article original article publishedVersion |