Bacillary angiomatosis with atypical clinical presentation in an immunocompetent patient


Autoria(s): Bernabeu-Wittel, J; Luque, R; Corbi, R; Mantrana-Bermejo, M; Navarrete, M; Vallejo, A; Bernabeu-Wittel, M
Data(s)

20/01/2015

20/01/2015

2010

Resumo

Bacillary angiomatosis is a recently described infectious disease that usually affects immunosupressed hosts with a previous history of contact with cats. We report a rare case of bacillary angiomatosis in an immunocompetent 59-year-old woman with no history of previous exposure to cats, and atypical clinical features (fever and subcutaneous nodules with ulceration on the left ankle). Histopathology of the lesion showed extensive ulceration and reactive tumor-like vascular proliferation of the blood vessels with swollen endothelial cells and an inflammatory infiltrate including neutrophils and lymphocytes in the dermis and subcutis. Staining with the Warthin-Starry method demonstrated the presence of clustered bacilli located in the extracellular matrix adjacent to the proliferating endothelial cells. Diagnosis was confirmed with the detection of Bartonella spp. DNA in the affected skin and in bone marrow using polymerase chain reaction.

Case Reports; Journal Article;

Identificador

Bernabeu-Wittel J, Luque R, Corbi R, Mantrana-Bermejo M, Navarrete M, Vallejo A, et al. Bacillary angiomatosis with atypical clinical presentation in an immunocompetent patient. Indian J Dermatol Venereol Leprol. 2010; 76(6):682-5

0973-3922 (Online)

0378-6323 (Print)

http://hdl.handle.net/10668/1792

21079313

10.4103/0378-6323.72469

Idioma(s)

en

Publicador

Medknow Publications

Relação

Indian Journal of Dermatology, Venereology and Leprology

http://www.ijdvl.com/article.asp?issn=0378-6323;year=2010;volume=76;issue=6;spage=682;epage=685;aulast=Bernabeu-Wittel

Direitos

Acceso abierto

Palavras-Chave #Bartonella quintana #Bartonella henselae #Immunocompetent #Infecciones por Bartonella #Proliferación de la Célula #Diagnóstico Diferencial #Doxiciclina #Endotelio Vascular #Huésped Inmunocomprometido #Angiomatosis Bacilar #Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Bartonellaceae Infections #Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation #Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnosis, Differential #Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Tetracyclines::Doxycycline #Medical Subject Headings::Anatomy::Tissues::Epithelium::Endothelium::Endothelium, Vascular #Medical Subject Headings::Check Tags::Female #Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans #Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunocompromised Host #Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged #Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Skin Diseases, Bacterial::Angiomatosis, Bacillary
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/published

Artículo