In vitro activity of fosfomycin against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: comparison of susceptibility testing procedures
| Data(s) |
18/03/2013
18/03/2013
01/01/2006
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| Resumo |
The agar dilution, broth microdilution, and disk diffusion methods were compared to determine the in vitro susceptibility of 428 extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae to fosfomycin. Fosfomycin showed very high activity against all ESBL-producing strains. Excellent agreement between the three susceptibility methods was found for E. coli, whereas marked discrepancies were observed for K. pneumoniae. Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; This study was partially supported by a grant from Pharmazan and was developed under the auspices of the Spanish Network for Research on Infectious Diseases (REIPI CO3/14; Instituto de Salud Carlos III, Madrid, Spain). |
| Identificador |
de Cueto M, López L, Hernández JR, Morillo C, Pascual A. In vitro activity of fosfomycin against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: comparison of susceptibility testing procedures. Antimicrob. Agents Chemother. 2006; 50(1):368-70 1098-6596 (Online) 0066-4804 (Print) PMC1346795 http://hdl.handle.net/10668/857 16377714 10.1128/AAC.50.1.368-370.2006 |
| Idioma(s) |
en |
| Publicador |
American Society for Microbiology |
| Relação |
Antimicrobial agents and chemotherapy http://aac.asm.org/content/50/1/368.abstract |
| Direitos |
Acceso abierto |
| Palavras-Chave | #Antibacterianos #Escherichia coli #Fosfomicina #Humanos #Infecciones por Klebsiella #Klebsiella pneumoniae #Pruebas de Sensibilidad Microbiana #Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents #Medical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Escherichia::Escherichia coli #Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Organophosphorus Compounds::Organophosphonates::Fosfomycin #Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans #Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Enterobacteriaceae Infections::Klebsiella Infections #Medical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Klebsiella::Klebsiella pneumoniae #Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Microbiological Techniques::Microbial Sensitivity Tests |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/published Artículo |
