Rheological behavior, zeta potential, and accelerated stability tests of Buriti oil (Mauritia flexuosa) emulsions containing lyotropic liquid crystals
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
---|---|
Data(s) |
19/10/2012
19/10/2012
2010
|
Resumo |
Background: It is well known that the Amazon region presents a huge biodiversity; therefore, countless natural resources are being employed in the production of phytocosmetics and phytomedicines. Objective: The purpose of this work was to obtain emulsions produced with Buriti oil and nonionic surfactants. Methods: Two surfactant systems were employed (Steareth-2 associated to Ceteareth-5 and to Ceteareth-20) to produce the emulsions using phase diagram method. Emulsions were obtained by echo-planar imaging method at 75 degrees C. Rheological behavior and zeta potential were evaluated, and accelerated stability tests were performed. Results: All emulsions analyzed presented pseudoplastic behavior. Zeta potential values were obtained between -14.2 and -53.3 mV. The formulations did not show changes in either physical stability, pH, or rheological behavior after accelerated stability tests. Significant differences were observed only after temperature cycling test. Conclusion: Based on these results, the emulsions obtained could be considered as promising delivery systems. CAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior) |
Identificador |
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, v.36, n.1, p.93-101, 2010 0363-9045 http://producao.usp.br/handle/BDPI/20169 10.3109/03639040903099728 |
Idioma(s) |
eng |
Publicador |
TAYLOR & FRANCIS INC |
Relação |
Drug Development and Industrial Pharmacy |
Direitos |
restrictedAccess Copyright TAYLOR & FRANCIS INC |
Palavras-Chave | #Buriti oil #emulsion #liquid crystal #nonionic surfactant #rheology #SURFACTANT SYSTEMS #BETA-CAROTENE #EMULSIFICATION #DRUG #PROTECTION #MICELLES #Chemistry, Medicinal #Pharmacology & Pharmacy |
Tipo |
article original article publishedVersion |