Oligo switches: photoresponsive oligonucleotide conjugates by solid-supported click chemistry

Autoria(s): Vyle, Joseph
Data(s)

12/02/2013
Resumo

Photoresponsive oligonucleotides (ONs) incorporating isoxazole-linked azobenzene (AB) moieties were prepared by resin-supported nitrile oxide-alkyne cycloaddition (NOAC) chemistry. The thermal and photochromic properties of the modified ONs were significantly influenced by the extent of pi-conjugation between the isoxazole and the AB modules.
Identificador

http://pure.qub.ac.uk/portal/en/publications/oligo-switches-photoresponsive-oligonucleotide-conjugates-by-solidsupported-click-chemistry(ff584415-5ce5-4bf5-a04b-955fceaec802).html

http://dx.doi.org/ 10.1039/c2ra22815g
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Vyle , J 2013 , ' Oligo switches: photoresponsive oligonucleotide conjugates by solid-supported click chemistry ' RSC Advances , vol 3 , no. 6 , DOI: 10.1039/c2ra22815g , pp. 1652-1655 . DOI: 10.1039/c2ra22815g
Palavras-Chave #COVALENT MODIFICATION #FUNCTIONALIZATION #AZOBENZENE #DNA HYBRIDIZATION
Tipo

article
Acesso ao item digital