Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome


Autoria(s): Fleseriu, Maria; Biller, Beverly M K; Findling, James W; Molitch, Mark E; Schteingart, David E; Gross, Coleman; SEISMIC Study Investigators; Lyons, Timothy
Data(s)

01/06/2012

Resumo

Cushing's syndrome (CS) is a disorder associated with significant morbidity and mortality due to prolonged exposure to high cortisol concentrations.

Identificador

http://pure.qub.ac.uk/portal/en/publications/mifepristone-a-glucocorticoid-receptor-antagonist-produces-clinical-and-metabolic-benefits-in-patients-with-cushings-syndrome(f2f14cb8-6c1d-4860-a591-e56e7da2b15e).html

http://dx.doi.org/10.1210/jc.2011-3350

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Fleseriu , M , Biller , B M K , Findling , J W , Molitch , M E , Schteingart , D E , Gross , C , SEISMIC Study Investigators & Lyons , T 2012 , ' Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome ' The Journal of clinical endocrinology and metabolism , vol 97 , no. 6 , pp. 2039-49 . DOI: 10.1210/jc.2011-3350

Palavras-Chave #Adult #Antihypertensive Agents #Blood Glucose #Blood Pressure #Body Composition #Body Weight #Cushing Syndrome #Diabetes Mellitus, Type 2 #Female #Glucose Intolerance #Hormone Antagonists #Humans #Hydrocortisone #Hypertension #Male #Middle Aged #Mifepristone #Quality of Life #Quinolines #Receptors, Glucocorticoid #Urea
Tipo

article