Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata


Autoria(s): Li, Ke; Li, Xiao-Ming; Ji, Nai-Yun; Gloer, James B.; Wang, Bin-Gui
Data(s)

03/04/2008

Resumo

6-Bromo-1-(3-bromo-4,5-dihydroxybenzyl)phenanthro[4,5-bcd]furan-2,3,5-triol (urceolatin, 1), a highly oxygenated bromophenol containing an unprecedented naturally occurring benzylphenanthro[4,5-bcd]furan unit, was isolated from the marine red alga Polysiphonia urceolata. Its structure was established on the basis of extensive spectroscopic analysis. Compound 1 displayed significant DPPH radical-scavenging activity with an IC50 value of 7.9 mu M, which is 10-fold more potent than that of the positive control, butylated hydroxytoluene.

6-Bromo-1-(3-bromo-4,5-dihydroxybenzyl)phenanthro[4,5-bcd]furan-2,3,5-triol (urceolatin, 1), a highly oxygenated bromophenol containing an unprecedented naturally occurring benzylphenanthro[4,5-bcd]furan unit, was isolated from the marine red alga Polysiphonia urceolata. Its structure was established on the basis of extensive spectroscopic analysis. Compound 1 displayed significant DPPH radical-scavenging activity with an IC(50) value of 7.9 mu M, which is 10-fold more potent than that of the positive control, butylated hydroxytoluene.

Identificador

http://ir.qdio.ac.cn/handle/337002/1636

http://www.irgrid.ac.cn/handle/1471x/166034

Idioma(s)

英语

Fonte

Li, Ke; Li, Xiao-Ming; Ji, Nai-Yun; Gloer, James B.; Wang, Bin-Gui.Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata,ORGANIC LETTERS,2008,10(7):1429-1432

Palavras-Chave #Chemistry, Organic #RADICAL-SCAVENGING ACTIVITY #ALGA LAURENCIA-DECUMBENS #RED ALGA #BLETILLA-STRIATA #ODONTHALIA CORYMBIFERA #SESQUITERPENES #RHODOMELACEAE
Tipo

期刊论文