Efficient synthesis of aryl hydroxylactams by reducing imides with activated zinc dust


Autoria(s): Yuan XH; Zhang MJ; Kang CQ; Guo HQ; Qiu XP; Gao LX
Data(s)

2006

Resumo

A series of aryl hydroxylactams (2a, 2b, 2d-2g, 2i-2k, 2m, and 2n) was synthesized by partially reducing aryl cyclic imides in moderate to excellent yields with activated zinc dust alone in acetic acid. This method was regiospecific and can be employed as an alternative for reported methods to partially reduce aryl cyclic imides.

Identificador

http://ir.ciac.jl.cn/handle/322003/16755

http://www.irgrid.ac.cn/handle/1471x/152466

Idioma(s)

英语

Fonte

Yuan XH;Zhang MJ;Kang CQ;Guo HQ;Qiu XP;Gao LX.Efficient synthesis of aryl hydroxylactams by reducing imides with activated zinc dust,SYNTHETIC COMMUNICATIONS,2006,36(4):435-444

Palavras-Chave #ALPHA-KETO CARBOXYLATES #NUCLEOPHILIC REACTIONS #DERIVATIVES #PHTHALIMIDES #REDUCTION #THALIDOMIDE #ANALOGS #AMINES
Tipo

期刊论文