Efficient synthesis of aryl hydroxylactams by reducing imides with activated zinc dust
Data(s) |
2006
|
---|---|
Resumo |
A series of aryl hydroxylactams (2a, 2b, 2d-2g, 2i-2k, 2m, and 2n) was synthesized by partially reducing aryl cyclic imides in moderate to excellent yields with activated zinc dust alone in acetic acid. This method was regiospecific and can be employed as an alternative for reported methods to partially reduce aryl cyclic imides. |
Identificador | |
Idioma(s) |
英语 |
Fonte |
Yuan XH;Zhang MJ;Kang CQ;Guo HQ;Qiu XP;Gao LX.Efficient synthesis of aryl hydroxylactams by reducing imides with activated zinc dust,SYNTHETIC COMMUNICATIONS,2006,36(4):435-444 |
Palavras-Chave | #ALPHA-KETO CARBOXYLATES #NUCLEOPHILIC REACTIONS #DERIVATIVES #PHTHALIMIDES #REDUCTION #THALIDOMIDE #ANALOGS #AMINES |
Tipo |
期刊论文 |