An economical, adaptable and user-friendly drip-perfusion bioreactor system designed for in vitro three dimensional cell culturing


Autoria(s): Leung, Leo
Data(s)

2016

Resumo

This research project investigated a bioreactor system capable of high density cell growth intended for use in regenerative medicine and protein production. The bioreactor was based on a drip-perfusion concept and constructed with minimal costs, readily available components, and straightforward processes for usage. This study involved the design, construction, and testing of the bioreactor where the results showed promising three dimensional cell growth within a polymer structure. The accessibility of this equipment and the capability of high density, three dimensional cell growth would be suitable for future research in pharmaceutical drug manufacturing, and human organ and tissue regeneration.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/92639/

Publicador

Queensland University of Technology

Relação

http://eprints.qut.edu.au/92639/1/Leo_Leung_Thesis.pdf

Leung, Leo (2016) An economical, adaptable and user-friendly drip-perfusion bioreactor system designed for in vitro three dimensional cell culturing. Masters by Research thesis, Queensland University of Technology.

Fonte

School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation

Palavras-Chave #drip-perfusion #bioreactor design #three dimensional cell culture #polymer scaffold #murine fibroblasts #inexpensive #adaptable #scalable design #protein production #tissue engineering
Tipo

Thesis