Ocorrência de Dictyla monotropidia Stål (Hemiptera: Tingidae) em Cordia verbenacea Al. DC no Brasil

Recently, Dictyla monotropidia Stal was observed feeding on plants of black sage (Cordia verbenacea Al. DC). The colonies of this insect were observed on abaxial surface of leaves, with nymphs and adults sucking the phloem sieve, causing spot, yellow aspect and leaf fall. D. monotropidia was already related as pest in other Cordia species in countries of Central and South America. Although, this is the first report of this insect attacking plants of C. verbenacea in Brazil.

Cordia verbenacea and secretion of mast cells in different animal species

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Rosmarinic acid, a new snake venom phospholipase A(2) inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction

Many plants are used in traditional medicine as active agents against various effects induced by snakebite. The methanolic extract from Cordia verbenacea (Cv) significantly inhibited paw edema induced by Bothrops jararacussu snake venom and by its main basic phospholipase A(2) homologs, namely bothropstoxins I and II (BthTXs). The active component was isolated by chromatography on Sephadex LH-20 and by RP-HPLC on a C18 column and identified as rosmarinic acid (Cv-RA). Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid [2-O-cafeoil-3-(3,4-di-hydroxy-phenyl)-R-lactic acid]. This is the first report of RA in the species C. verbenacea ('baleeira', 'whaler') and of its anti-inflammatory and antimyotoxic properties against snake venoms and isolated toxins. RA inhibited the edema and myotoxic activity induced by the basic PLA(2)s BthTX-I and BthTX-II. It was, however, less efficient to inhibit the PLA(2) activity of BthTX-II and, still less, the PLA(2) and edema-inducing activities of the acidic isoform BthA-1-PLA(2), from the same venom, showing therefore a higher inhibitory activity upon basic PLA(2)s. RA also inhibited most of the myotoxic and partially the edema-inducing effects of both basic PLA(2)s, thus reinforcing the idea of dissociation between the catalytic and pharmacological domains. The pure compound potentiated the ability of the commercial equine polyvalent antivenom in neutralizing lethal and myotoxic effects of the crude venom and of isolated PLA(2)s in experimental models. CD data presented here suggest that, after binding, no significant conformation changes occur either in the Cv-RA or in the target PLA(2). A possible model for the interaction of rosmarinic acid with Lys49-PLA(2) BthTX-I is proposed. (c) 2005 Elsevier Ltd. All rights reserved.

Evaluation of the antiulcerogenic and analgesic activities of Cordia verbenacea DC. (Boraginaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cordia verbenacea DC: perfil morfo-anatômico, histoquímico, farmacognóstico e avaliação da atividade anti-candida do extrato hidroetanólico e suas frações

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Variabilidade genética em uma população de Cordia verbenacea DC. para características agronômicas e fitoquímicas

Pós-graduação em Agronomia (Horticultura) - FCA

Análise da atividade antimicrobiana dos extratos de Cordia verbenacea DC, Mikania laevigata Sch. Bip. ex Baker e Psidium Cattleianum frente a microrganismos endodônticos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Integração de métodos físicos e biológicos no controle de doenças em viveiros de plantas medicinais: estudo de caso com Cordia verbenacea.

2009

Crystallization and preliminary X-ray crystallographic studies of a Lys49-phospholipase A(2) homologue from Bothrops pirajai venom complexed with rosmarinic acid

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Patents of drugs extracted from Brazilian medicinal plants

Background: Plants synthesise a vast repertoire of chemicals with various biological activities. Brazilian enormous botanical diversity facilitates the development of novel ethical drugs for the treatment of diseases in humans. Objective: To present therapeutic patent applications comprising Brazilian native plants published in the 2003 - 2008 period in light of legal aspects of patentability of biodiversity and public health concerns. Methods: Therapeutic patent applications related to Brazilian medicinal plants available at both the European Patent Office and the Brazilian National Institute of industrial Property databases were reviewed. Results/conclusion: Twenty-five patents are presented, most of which concern inflammatory, allergic, parasitic, infectious or digestive diseases, including extracts from Carapa guianensis, Copaifera genus, Cordia verbenacea, Erythrina mulungu, Physalis angulata and other pharmaceutical compositions with antileishmanial, antimalarial or trypanocidal activity. Brazilian research centres and universities are responsible for most of these inventions.

Multiplicação do nematoide Meloidogyne paranaensis e velocidade de enraizamento de estacas caulinares em sete espécies de plantas medicinais

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Programa de Pós-Graduação em Agronomia, 2016.

Estudio de oferta y demanda de Laurel (Cordia alliodora (Ruiz y Pavón)) Oken., en los municipios de Nandaime, Granada y Masaya, Nicaragua

El objetivo principal del estudio fue determinar los componentes de mercado, oferta y demanda de laurel (Cordia alliodora) en los Municipios de Nandaime, Granada y Masaya en el periodo Enero - Julio 2002. Para el levantamiento de la información se diseño una metodología basada en el sondeo, utilizando la encuesta como técnica principal para la recolección de los datos. Se diseñaron tres tipos de entrevistas de acuerdo con la información que se requería (aserraderos, carpinterías y mueblerías), las cuales identificarían el mercado local de la madera de laurel, precio y características demandadas. Se estudiaron 18 carpinterías que corresponden al 100 %de la muestra. Estas demandaron 32 550 pulgadas de madera de laurel, equivalente a 13.02 fletes. Se identificaron dos formas de comercialización de la madera de laurel. La primera es la forma legal que cumple con los requisitos de permisos e impuestos de acuerdo a la ley, y la segunda es la forma ilegal, obviando los pagos de permisos, impuestos y demás conforme a la ley. Los principales consumidores de la madera de laurel proceden los municipios estudiados y otros procedentes de las ciudades de Carazo, Rivas, Managua y Tipitapa. Los productos más comercializados en los puestos de venta corresponden a medidas para tablas de 1" X 16" X 4V y 1" X 12" X 5V, tablones de 2" X 6" X 4V y Alfajillas con medidas de 1" X 2" X 5V. Los productos más comercializados en las carpinterías son sillas, camas, roperos, puertas y comedores. Los factores principales que intervienen en la oferta y la demanda de madera de laurel, son: la poca cantidad de madera ofrecida, el alto valor de esta madera y del producto acabado, árboles aprovechados sin alcanzar el diámetro mínimo de corta, los gustos, y la capacidad adquisitiva del demandante. La estructura de costos indica que en el proceso legal de aprovechamiento, los gastos en concepto de pago de permisos e impuestos son excesivos, lo cual encarece el producto al consumidor final. El mercado legal más activo para esta madera es el de Masaya, debido a la presencia de un mayor número de carpinterías y puestos de venta que lo vuelven más competitivo. El hecho que este retirado de la zona rural permite que disminuya la competencia con el mercado negro de la madera, una ventaja al momento de la comercialización. Se proyecta que la demanda de madera aumentará a razón de 1.10 m' por año. Esta demanda es baja, pero se debe tomar en cuenta que está en función de la cantidad ofertada, si esta aumenta, aunmentara también la demanda.

Ocorrência de Dictyla monotropidia (Hemiptera: Tingidae) em louro-pardo, Cordia trichotoma.

2009

Fenología floral de la anacahuita (cordia boissieri) y su relación con sus visitantes florales.

Tesis (Maestría en Ciencias Forestales) UANL, 2011.

Efeitos de um extrato aquoso de porangaba (Cordia salicifolia) na marcação de constituintes sanguíneos com tecnécio-99m e na morfologia de hemácias

Effects of a Cordia salicifolia (porangaba) extract on the labeling of blood cells (BCs) with technetium-99m ((99m)Tc) and on the morphology of red BCs were evaluated. Labeling of cellular and molecular structures with (99m)Tc depends on a reducing agent. Some physical characteristics, as visible absorbance spectrum, electric conductivity, and refractive index of this porangaba extract, were also determined. Blood samples from Wistar rats were incubated with porangaba extract or with 0.9% NaCl (control). Labeling of blood constituents with (99m)Tc was performed. Plasma (P) and BCs, both soluble (SF-P and SF-BC) and insoluble (IF-P and IF-BC) fractions, were separated. The radioactivity in each fraction was counted, and the percentage of radioactivity incorporated (%ATI) was calculated. Blood smears were prepared, fixed, and stained, and the morphology of the red BCs was evaluated. Data showed an absorbance peak at 480 nm and electric conductibility and refractive index concentration-dependent. Porangaba extract decreased significantly (P < .05) the BC, IF-P, and IF-BC %ATI, and no modifications were verified on the shape of red BCs. Analysis of the results reveals that some physical parameters could be useful to aid in characterizing the extract studied. Moreover, it is possible that chemical compounds of this extract could have chelating/redox actions or be capable of binding to plasma and/or cellular proteins