65 resultados para DNA Sequence, Hidden Markov Model, Bayesian Model, Sensitive Analysis, Markov Chain Monte Carlo

em Deakin Research Online - Australia


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The work presented in this paper focuses on fitting of a neural mass model to EEG data. Neurophysiology inspired mathematical models were developed for simulating brain's electrical activity imaged through Electroencephalography (EEG) more than three decades ago. At the present well informative models which even describe the functional integration of cortical regions also exists. However, a very limited amount of work is reported in literature on the subject of model fitting to actual EEG data. Here, we present a Bayesian approach for parameter estimation of the EEG model via a marginalized Markov Chain Monte Carlo (MCMC) approach.

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Permutation modeling is challenging because of the combinatorial nature of the problem. However, such modeling is often required in many real-world applications, including activity recognition where subactivities are often permuted and partially ordered. This paper introduces a novel Hidden Permutation Model (HPM) that can learn the partial ordering constraints in permuted state sequences. The HPM is parameterized as an exponential family distribution and is flexible so that it can encode constraints via different feature functions. A chain-flipping Metropolis-Hastings Markov chain Monte Carlo (MCMC) is employed for inference to overcome the O(n!) complexity. Gradient-based maximum likelihood parameter learning is presented for two cases when the permutation is known and when it is hidden. The HPM is evaluated using both simulated and real data from a location-based activity recognition domain. Experimental results indicate that the HPM performs far better than other baseline models, including the naive Bayes classifier, the HMM classifier, and Kirshner's multinomial permutation model. Our presented HPM is generic and can potentially be utilized in any problem where the modeling of permuted states from noisy data is needed.

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Introduced in this paper is a Bayesian model for isolating the resonant frequency from combustion chamber resonance. The model shown in this paper focused on characterising the initial rise in the resonant frequency to investigate the rise of in-cylinder bulk temperature associated with combustion. By resolving the model parameters, it is possible to determine: the start of pre-mixed combustion, the start of diffusion combustion, the initial resonant frequency, the resonant frequency as a function of crank angle, the in-cylinder bulk temperature as a function of crank angle and the trapped mass as a function of crank angle. The Bayesian method allows for individual cycles to be examined without cycle-averaging|allowing inter-cycle variability studies. Results are shown for a turbo-charged, common-rail compression ignition engine run at 2000 rpm and full load.

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A novel in-cylinder pressure method for determining ignition delay has been proposed and demonstrated. This method proposes a new Bayesian statistical model to resolve the start of combustion, defined as being the point at which the band-pass in-cylinder pressure deviates from background noise and the combustion resonance begins. Further, it is demonstrated that this method is still accurate in situations where there is noise present. The start of combustion can be resolved for each cycle without the need for ad hoc methods such as cycle averaging. Therefore, this method allows for analysis of consecutive cycles and inter-cycle variability studies. Ignition delay obtained by this method and by the net rate of heat release have been shown to give good agreement. However, the use of combustion resonance to determine the start of combustion is preferable over the net rate of heat release method because it does not rely on knowledge of heat losses and will still function accurately in the presence of noise. Results for a six-cylinder turbo-charged common-rail diesel engine run with neat diesel fuel at full, three quarters and half load have been presented. Under these conditions the ignition delay was shown to increase as the load was decreased with a significant increase in ignition delay at half load, when compared with three quarter and full loads.

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Likelihood computation in spatial statistics requires accurate and efficient calculation of the normalizing constant (i.e. partition function) of the Gibbs distribution of the model. Two available methods to calculate the normalizing constant by Markov chain Monte Carlo methods are compared by simulation experiments for an Ising model, a Gaussian Markov field model and a pairwise interaction point field model.

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Learning preference models from human generated data is an important task in modern information processing systems. Its popular setting consists of simple input ratings, assigned with numerical values to indicate their relevancy with respect to a specific query. Since ratings are often specified within a small range, several objects may have the same ratings, thus creating ties among objects for a given query. Dealing with this phenomena presents a general problem of modelling preferences in the presence of ties and being query-specific. To this end, we present in this paper a novel approach by constructing probabilistic models directly on the collection of objects exploiting the combinatorial structure induced by the ties among them. The proposed probabilistic setting allows exploration of a super-exponential combinatorial state-space with unknown numbers of partitions and unknown order among them. Learning and inference in such a large state-space are challenging, and yet we present in this paper efficient algorithms to perform these tasks. Our approach exploits discrete choice theory, imposing generative process such that the finite set of objects is partitioned into subsets in a stagewise procedure, and thus reducing the state-space at each stage significantly. Efficient Markov chain Monte Carlo algorithms are then presented for the proposed models. We demonstrate that the model can potentially be trained in a large-scale setting of hundreds of thousands objects using an ordinary computer. In fact, in some special cases with appropriate model specification, our models can be learned in linear time. We evaluate the models on two application areas: (i) document ranking with the data from the Yahoo! challenge and (ii) collaborative filtering with movie data. We demonstrate that the models are competitive against state-of-the-arts.

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An experimental study has been performed to investigate the ignition delay of a modern heavy-duty common-rail diesel engine run with fumigated ethanol substitutions up to 40% on an energy basis. The ignition delay was determined through the use of statistical modelling in a Bayesian framework this framework allows for the accurate determination of the start of combustion from single consecutive cycles and does not require any differentiation of the in-cylinder pressure signal. At full load the ignition delay has been shown to decrease with increasing ethanol substitutions and evidence of combustion with high ethanol substitutions prior to diesel injection have also been shown experimentally and by modelling. Whereas, at half load increasing ethanol substitutions have increased the ignition delay. A threshold absolute air to fuel ratio (mole basis) of above ~110 for consistent operation has been determined from the inter-cycle variability of the ignition delay, a result that agrees well with previous research of other in-cylinder parameters and further highlights the correlation between the air to fuel ratio and inter-cycle variability. Numerical modelling to investigate the sensitivity of ethanol combustion has also been performed. It has been shown that ethanol combustion is sensitive to the initial air temperature around the feasible operating conditions of the engine. Moreover, a negative temperature coefficient region of approximately 900{1050 K (the approximate temperature at fuel injection) has been shown with for n-heptane and n-heptane/ethanol blends in the numerical modelling. A consequence of this is that the dominate effect influencing the ignition delay under increasing ethanol substitutions may rather be from an increase in chemical reactions and not from in-cylinder temperature. Further investigation revealed that the chemical reactions at low ethanol substitutions are different compared to the high (> 20%) ethanol substitutions.

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For clinical use, in electrocardiogram (ECG) signal analysis it is important to detect not only the centre of the P wave, the QRS complex and the T wave, but also the time intervals, such as the ST segment. Much research focused entirely on qrs complex detection, via methods such as wavelet transforms, spline fitting and neural networks. However, drawbacks include the false classification of a severe noise spike as a QRS complex, possibly requiring manual editing, or the omission of information contained in other regions of the ECG signal. While some attempts were made to develop algorithms to detect additional signal characteristics, such as P and T waves, the reported success rates are subject to change from person-to-person and beat-to-beat. To address this variability we propose the use of Markov-chain Monte Carlo statistical modelling to extract the key features of an ECG signal and we report on a feasibility study to investigate the utility of the approach. The modelling approach is examined with reference to a realistic computer generated ECG signal, where details such as wave morphology and noise levels are variable.

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In this paper, we present a method for recognising an agent's behaviour in dynamic, noisy, uncertain domains, and across multiple levels of abstraction. We term this problem on-line plan recognition under uncertainty and view it generally as probabilistic inference on the stochastic process representing the execution of the agent's plan. Our contributions in this paper are twofold. In terms of probabilistic inference, we introduce the Abstract Hidden Markov Model (AHMM), a novel type of stochastic processes, provide its dynamic Bayesian network (DBN) structure and analyse the properties of this network. We then describe an application of the Rao-Blackwellised Particle Filter to the AHMM which allows us to construct an efficient, hybrid inference method for this model. In terms of plan recognition, we propose a novel plan recognition framework based on the AHMM as the plan execution model. The Rao-Blackwellised hybrid inference for AHMM can take advantage of the independence properties inherent in a model of plan execution, leading to an algorithm for online probabilistic plan recognition that scales well with the number of levels in the plan hierarchy. This illustrates that while stochastic models for plan execution can be complex, they exhibit special structures which, if exploited, can lead to efficient plan recognition algorithms. We demonstrate the usefulness of the AHMM framework via a behaviour recognition system in a complex spatial environment using distributed video surveillance data.

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In this paper, we consider the problem of tracking an object and predicting the object's future trajectory in a wide-area environment, with complex spatial layout and the use of multiple sensors/cameras. To solve this problem, there is a need for representing the dynamic and noisy data in the tracking tasks, and dealing with them at different levels of detail. We employ the Abstract Hidden Markov Models (AHMM), an extension of the well-known Hidden Markov Model (HMM) and a special type of Dynamic Probabilistic Network (DPN), as our underlying representation framework. The AHMM allows us to explicitly encode the hierarchy of connected spatial locations, making it scalable to the size of the environment being modeled. We describe an application for tracking human movement in an office-like spatial layout where the AHMM is used to track and predict the evolution of object trajectories at different levels of detail.

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We present an independent evaluation of six recent hidden Markov model (HMM) genefinders. Each was tested on the new dataset (FSH298), the results of which showed no dramatic improvement over the genefinders tested five years ago. In addition, we introduce a comprehensive taxonomy of predicted exons and classify each resulting exon accordingly. These results are useful in measuring (with finer granularity) the effects of changes in a genefinder. We present an analysis of these results and identify four patterns of inaccuracy common in all HMM-based results.

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Directly modeling the inherent hierarchy and shared structures of human behaviors, we present an application of the hierarchical hidden Markov model (HHMM) for the problem of activity recognition. We argue that to robustly model and recognize complex human activities, it is crucial to exploit both the natural hierarchical decomposition and shared semantics embedded in the movement trajectories. To this end, we propose the use of the HHMM, a rich stochastic model that has been recently extended to handle shared structures, for representing and recognizing a set of complex indoor activities. Furthermore, in the need of real-time recognition, we propose a Rao-Blackwellised particle filter (RBPF) that efficiently computes the filtering distribution at a constant time complexity for each new observation arrival. The main contributions of this paper lie in the application of the shared-structure HHMM, the estimation of the model's parameters at all levels simultaneously, and a construction of an RBPF approximate inference scheme. The experimental results in a real-world environment have confirmed our belief that directly modeling shared structures not only reduces computational cost, but also improves recognition accuracy when compared with the tree HHMM and the flat HMM.

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Binary signatures have been widely used to detect malicious software on the current Internet. However, this approach is unable to achieve the accurate identification of polymorphic malware variants, which can be easily generated by the malware authors using code generation engines. Code generation engines randomly produce varying code sequences but perform the same desired malicious functions. Previous research used flow graph and signature tree to identify polymorphic malware families. The key difficulty of previous research is the generation of precisely defined state machine models from polymorphic variants. This paper proposes a novel approach, using Hierarchical Hidden Markov Model (HHMM), to provide accurate inductive inference of the malware family. This model can capture the features of self-similar and hierarchical structure of polymorphic malware family signature sequences. To demonstrate the effectiveness and efficiency of this approach, we evaluate it with real malware samples. Using more than 15,000 real malware, we find our approach can achieve high true positives, low false positives, and low computational cost.