The genome sequence of the plant pathogen Xylella fastidiosa: The Xylella fastidiosa consortium of the organization for nucleotide sequencing and analysis, Sao Paulo, Brazil
Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
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Data(s) |
27/05/2014
27/05/2014
13/07/2000
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Resumo |
Xylella fastidiosa is a fastidious, xylem-limited bacterium that causes a range of economically important plant diseases. Here we report the complete genome sequence of X. fastidiosa clone 9a5c, which causes citrus variegated chlorosis - a serious disease of orange trees. The genome comprises a 52.7% GC-rich 2,679,305-base-pair (bp) circular chromosome and 'two plasmids of 51,158 bp and 1,285 bp. We can assign putative functions to47% of the 2,904 predicted coding regions. Efficient metabolic functions are predicted, with sugars as the principal energy and carbon source, supporting existence in the nutrient-poor xylem sap. The mechanisms associated with pathogenicity and virulence involve toxins, antibiotics and ion sequestration systems, as well as bacterium-bacterium and bacterium-host interactions mediated by a range of proteins. Orthologues of some of these proteins have only been identified in animal and human pathogens; their presence in X. fastidiosa indicates that the molecular basis for bacterial pathogenicity is both conserved and independent of host. At least 83 genes are bacteriophage-derived and include virulence-associated genes from other bacteria, providing direct evidence of phage-mediated horizontal gene transfer. |
Formato |
151-157 |
Identificador |
http://dx.doi.org/10.1038/35018003 Nature, v. 406, n. 6792, p. 151-157, 2000. 0028-0836 http://hdl.handle.net/11449/132388 10.1038/35018003 WOS:000088221100037 2-s2.0-0034644159 |
Idioma(s) |
eng |
Publicador |
Macmillan Publishers Ltd |
Relação |
Nature |
Direitos |
closedAccess |
Palavras-Chave | #carrier protein #bacterial genetics #bacterial metabolism #bacterium #bacterium adherence #energy metabolism #gene sequence #genetic conservation #genetic transcription #genome #nonhuman #nucleotide sequence #plant #priority journal #review #sequence analysis #Bacterial Adhesion #Bacterial Proteins #Biological Transport #Chromosome Mapping #Citrus #DNA Repair #DNA, Bacterial #Energy Metabolism #Genome, Bacterial #Molecular Sequence Data #Plants #Plants, Toxic #Protein Biosynthesis #Pseudomonadaceae #Sequence Analysis, DNA #Tobacco #Transcription, Genetic #Virulence #Animalia #Bacteria (microorganisms) #Citrus sinensis #Fungi #Xylella fastidiosa |
Tipo |
info:eu-repo/semantics/article |