Atenolol reduces salivary activity in pups of spontaneously hypertensive and normotensive rats treated during pregnancy and lactation
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
27/05/2014
27/05/2014
01/02/2008
|
| Resumo |
The salivary activity in pups of spontaneously hypertensive rats (SHR) and Wistar (W) rats treated with atenolol during pregnancy, and lactation was evaluated. Atenolol's anti-hypertensive effect on the SHR rats was noticed from the beginning of treatment. Atenolol-treated SHR and Wistar rat pups showed a decrease in salivary gland weight, salivary flow, and protein concentration, with no alteration in salivary amylase activity. Atenolol's effect on salivary glands can interfere with oral health maintenance. Copyright © Informa Healthcare USA, Inc. |
| Formato |
133-141 |
| Identificador |
http://dx.doi.org/10.1080/10641960801931923 Clinical and Experimental Hypertension, v. 30, n. 2, p. 133-141, 2008. 1064-1963 1525-6006 http://hdl.handle.net/11449/70294 10.1080/10641960801931923 2-s2.0-39749168317 |
| Idioma(s) |
eng |
| Relação |
Clinical and Experimental Hypertension |
| Direitos |
closedAccess |
| Palavras-Chave | #Atenolol #Salivary glands #Spontaneously hypertensive rats (SHR) #amylase #atenolol #animal experiment #animal model #antihypertensive activity #controlled study #enzyme activity #female #health #hypertension #lactation #male #nonhuman #pregnancy #rat #salivary gland #salivation #Adrenergic beta-Antagonists #Amylases #Animals #Female #Hypertension #Lactation #Male #Organ Size #Osmolar Concentration #Pregnancy #Pregnancy Complications, Cardiovascular #Rats #Rats, Inbred SHR #Rats, Wistar #Saliva #Salivary Glands #Salivary Proteins |
| Tipo |
info:eu-repo/semantics/article |
