Effects of treatment, awareness and condom use in a coinfection model for HIV and HCV in MSM


Autoria(s): Pinto, Carla M.A.; Carvalho, Ana R.M.
Data(s)

07/01/2016

07/01/2016

2015

Resumo

We develop a new a coinfection model for hepatitis C virus (HCV) and the human immunodeficiency virus (HIV). We consider treatment for both diseases, screening, unawareness and awareness of HIV infection, and the use of condoms. We study the local stability of the disease-free equilibria for the full model and for the two submodels (HCV only and HIV only submodels). We sketch bifurcation diagrams for different parameters, such as the probabilities that a contact will result in a HIV or an HCV infection. We present numerical simulations of the full model where the HIV, HCV and double endemic equilibria can be observed. We also show numerically the qualitative changes of the dynamical behavior of the full model for variation of relevant parameters. We extrapolate the results from the model for actual measures that could be implemented in order to reduce the number of infected individuals.

Identificador

http://hdl.handle.net/10400.22/7319

10.1142/S0218339015500096

Idioma(s)

eng

Publicador

World Scientific

Relação

Journal of Biological Systems;Vol. 23, Issue 02

http://www.worldscientific.com/doi/abs/10.1142/S0218339015500096

Direitos

openAccess

Palavras-Chave #Mathematical Models #HIV/AIDS #HCV #MSM #Screening Coinfection
Tipo

article