Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles
Data(s) |
2003
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Resumo |
Recent studies have focused on the structural features of DNA-lipid assemblies. In this paper we take nile blue A (NBA) as a probe molecule to study the influence of the conformational transition of DNA induced by didodecyldimethylammonium bromide (DDAB) cationic vesicles to the interaction between DNA and the probe molecules. We find that upon binding to DNA, a secondary conformational transition of DNA induced by the cationic liposome from the native B-form to the C-form resulted in the change of binding modes of NBA to DNA and different complexes are formed between DNA, DDAB and NBA. |
Identificador | |
Idioma(s) |
英语 |
Fonte |
Zhang ZL;Huang WM;Wang EK;Dong SJ.Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles,SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2003,59(2 ):255-263 |
Palavras-Chave | #CALF THYMUS DNA #LIPOSOME COMPLEXES #BINDING #PORPHYRINS #MEMBRANES #POLYMERS #BILAYERS |
Tipo |
期刊论文 |