Estudo da viabilidade econômica em campos maduros

When it comes to oil and gas in Brazil is almost certain that we are referring to activities in deep waters off the coast of Campos, Rio de Janeiro, the main field of action of PETROBRAS and a small number of multinational oil companies . Since the Law 9.478/97 allows, by means of concessions, that other companies other than Petrobras, to explore and produce oil and gas domestically. Soon it moved, then the private companies that want small and medium-sized businesses to invest in such activities, forming a segment of independent producers, as occurs in other countries. In this context, this work aims at making an economic feasibility study, is currently analyzing how this thread and focus on the factors that contribute to its development as well as those that constitute barriers. To this end, we conducted a survey examining some mature fields that are in production in order to capture cost information in the phases of project, operation and abandonment. The work also presents an analysis of the results obtained in the survey, identifying the costs higher. With the results obtained through the study used economic engineering tools such as NPV and IRR, using a variety of design scenarios, to study the economic viability of these fields. In scenario 4 was set a production of 4.0 m³ / d of oil, which is an expected average production for several of these fields, whose minimum value of a barrel of oil, to enable this field, was $ 55.00, this value well below what was being practiced in the market today.

Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol

Flavopiridol has been shown to potently inhibit CDK1 and 2 (cyclin-dependent kinases 1 and 2) and most recently it has been found that it also inhibits CDK9. The complex CDK9-cyclin T1 controls the elongation phase of transcription by RNA polymerase II. The present work describes a molecular model for the binary complex CDK9-flavopiridol. This structural model indicates that the inhibitor strongly binds to the ATP-binding pocket of CDK9 and the structural comparison of the complex CDK2-flavopiridol correlates the structural differences with differences in inhibition of these CDKs by flavopiridol. This structure opens the possibility of testing new inhibitor families, in addition to new substituents for the already known leading structures such as flavones and adenine derivatives. © 2002 Elsevier Science (USA). All rights reserved.

Estudo da viabilidade econômica em campos maduros

When it comes to oil and gas in Brazil is almost certain that we are referring to activities in deep waters off the coast of Campos, Rio de Janeiro, the main field of action of PETROBRAS and a small number of multinational oil companies . Since the Law 9.478/97 allows, by means of concessions, that other companies other than Petrobras, to explore and produce oil and gas domestically. Soon it moved, then the private companies that want small and medium-sized businesses to invest in such activities, forming a segment of independent producers, as occurs in other countries. In this context, this work aims at making an economic feasibility study, is currently analyzing how this thread and focus on the factors that contribute to its development as well as those that constitute barriers. To this end, we conducted a survey examining some mature fields that are in production in order to capture cost information in the phases of project, operation and abandonment. The work also presents an analysis of the results obtained in the survey, identifying the costs higher. With the results obtained through the study used economic engineering tools such as NPV and IRR, using a variety of design scenarios, to study the economic viability of these fields. In scenario 4 was set a production of 4.0 m³ / d of oil, which is an expected average production for several of these fields, whose minimum value of a barrel of oil, to enable this field, was $ 55.00, this value well below what was being practiced in the market today.

Na 1 Nachlass Max Horkheimer, 55 - Korrespondenzen u.a. mit Julien Wavrinek und Walter Benjamin (p. I 26, 1-130)

2 Briefe zwischen Marga Wadsack und Max Horkheimer, 24.08.1937, 29.08.1937; 1 Brief von Gloria H. Wagner an Max Horkheimer, 27.12.1948; 1 Brief von Herta Wagner an Leo Löwenthal, 05.06.1936; 3 Brief und 1 Beilage zwischen Herta Wagner, 12.03.1936, 1936; 8 Brief zwischen Katja Walch-Lux und Max Horkheimer, 1934-1938; 2 Brief zwischen K. Walcher und Max Horkheimer, 07.08.1936, 04.09.1936 sowie Bemerkungen zum Brief von Max Horkheimer; 2 Briefe zwischen Morris Waldman und Max Horkheimer, 17.04.1940, 11.05.1940; 6 Briefe zwischen Sidney Wallach und Max Horkheimer, 1940; 2 Briefe von Max Horkheimer an Waldman; 2 Briefe von Max Horkheimer an Landau; 1 Brief Max Horkheimer an Warburg; 1 Brief von Hans Wallenberg an Leo Löwenthal, 06.05.1940; 1 Brief von Willard W. Waller an Franz Neumann, 28.04.1941; 2 Briefe und 1 Beilage zwischen Hans Waloschek und Max Horkheimer, 04.08.1938, 31.08.1938; 4 Briefe und 2 Beilagen zwischen Emil J. Walter und Max Horkheimer, 1937, 1938; 5 Briefe und 1 Beilage zwischen Hilde Walter und Max Horkheimer, 1937, 1945; 1 Brief von Rose Walter an Max Horkheimer, 16.11.1938; 2 Briefe zwischen Yu-Chuan Wang und Max Horkheimer, 12.10.1936, 09.12.1936; 1 Brief von Rike Wankmüller-Freyh an Max Horkheimer, 06.07.1949; 1 Brief von Ilse Bach an Heinz Wartenberg, 11.11.1940; 1 Brief von Heinz Wartenberg an Richard Bach, 07.02.1941; 1 Brief von Max Horkheimer an Heinz Wartenberg, 11.03.1941; 1 Brief von Richard Bach an Max Horkheimer; 1 Brief von Franz und Hilde Wasem an Max Horkheimer, 16.02.1949; 5 Briefe zwischen Goodwin Watson und Franz Neumann, 1941; 11 Briefe und Notizen zwischen Julien Wavrinek und Max Horkheimer, 1938-1940; 1 Brief von Max Horkheimer an M. Bruhat; 2 Briefe von Max Horkheimer an Walter Benjamin, 03.05.1940;

Na 1 Nachlass Max Horkheimer, 242 - Korrespondenzen u.a. mit Bibliothekaren der Deutschen Bibliothek in Rom (p. V 55, 1-303)

1 Brief an Max Horkheimer von der Oberin, Agnes Karll-Verband Ruth Elster, 1959; 1 Brief von Max Horkheimer an Fernanda Alves Diniz, 1959; 4 Briefe zwischen Journalist Walter Dirks, 1950-1955; 1 Interview mit Max Horkheimer, von Journalist, Tel-Aviv Dr. Dolan, 1952; 2 Briefe zwischen Albert Dragstedt und Max Horkheimer, 1959; 17 Briefe zwischen Ria Drevermann und Max Horkheimer, 1948-1957; 4 Briefe zwischen Architekt Wolf Drevermann und Max Horkheimer, 1950-1952; Professor Kurt Rheindorf: 1 Lebenslauf, 1 Manuskript, (1949); 2 Briefe zwischen Dr. Josef E. Drexel und Max Horkheimer, 1958; 3 Briefe zwischen Professor Tom F. Driver und Max Horkheimer, 1966; 12 Briefe zwischen dem DuMont Schuaberg Verlag und Max Horkheimer, 1961-1966; Deutsch-Amerikanischer Beratungs-Ausschuss für das Land Hessen: Drucksachen, Notizen, Protokolle an Max Horkheimer, 1952-1967; 1 Brief an Max Horkheimer von Hartmut Höschel, 1967; 14 Briefe zwischen Deutsche Bibliothek, Brüssel und Max Horkheimer, 1970-1971; 8 Briefe zwischen Deutsche Bibliothek Frankfurt am Main und Max Horkheimer, 1965-1967; 47 briefe zwischen Johannes Vandenrath, Deutsche Bibliothek Mailand und Max Horkheimer, 1968-1973; 51 Briefe zwischen Michael Freiherr Marschall von Bieberstein, Deutsche Bibliothek Rom, und Max Horkheimer, 1968-1973; Deutsche Bibliothek Rom: siehe Marschall von Bieberstein, Michael Freiherr;

The Taiwan Strait Crisis of 1954-55 and U.S.-R.O.C Relations

On September 3, 1954, Chinese artillery began shelling Quemoy (Jinmen), one of the Kuomintang-held offshore islands, setting off the first Taiwan Strait Crisis. This paper focuses on the crisis and analyzes the following three questions: (1) What was the policy the U.S. took towards the Republic of China (R.O.C), especially towards the offshore islands, to try to end the Taiwan Strait Crisis? (2) What were the intentions of the U.S. government in trying to end the Taiwan Strait Crisis? And (3) how should U.S. policy towards the R.O.C. which led to solving the Taiwan Strait Crisis be positioned in the history of Sino-American relations? Through analysis of these questions, this study concludes that the position the U.S. took to bring an end to crisis, one which prevented China from “liberating Taiwan” and the Kuomintang from “attacking the mainland,” brought about the existence of a de facto “two-China” situation.

Review of information on the safety effects of the 55 mph speed limit in the U.S.

Mode of access: Internet.

Triumphlied : (Offenb. Joh. Cap. 19) für achtstimmigen Chor u. Orchester (Orgel ad libitum) : Op. 55.

Mode of access: Internet.

U.S. grain exports under government programs : 1954-55 through 1959-60 /

Chiefly tables.

Federal aid primary route 340 interstate route 55 to interstate route 80 Cook, DuPage, and Will Counties : final environmental impact statement and section 4(f) evaluation : submitted pursuant to 42 U.S.C. 4332(2)(c) and 49 U.S.C. 303 /

"FHWA-IL-EIS-93-03-D/4(F)"

Haupt-register über die verhandlungen der Stände des Königreichs Württemberg auf den Landtagen von 1833-55.

Mode of access: Internet.

Tension-Free Vaginal Tape (T.V.T) - Nova e Revolucionária Técnica para o Tratamento Cirúrgico da Incontinência Urinária de Esforço (I.U.E.) Feminina Introduzida na MAC pelo Núcleo de Ginecologia Urológica

Este artigo pretende fazer uma revisão de uma das últimas e inovadoras alternativas cirúrgicas viáveis para a cura da incontinência urinária de esforço feminina, com um sucesso superior a 86%. É uma cirurgia mini invasiva e que induz um suporte da uretra média livre de tensão, muito eficaz. Tem vantagens, poucas complicações, curto tempo operatório e benefícios para a doente no pós-operatório imediato e tardio.

Tradição e tradução: festa e etnicidade entre os imigrantes açorianos nos E.U.A.

Desde finais do século XIX que se desenvolveu, nos estados norte- -americanos de Massachusetts (MA) e de Rhode Island (RI), uma importante comunidade de origem portuguesa. De acordo com o censo norte-americano de 1990, essa comunidade é composta por um total de 320.000 pessoas de portuguese ancestry. Tendo sido freqüentemente descrita como uma minoria étnica "invisível" (cf Smith, 1978), ela tem entretanto uma presença importante em cidades como Fali River e New Bedford - no sudeste de Massachusetts - ou East Providence - Rhode Island - onde representa entre 40 a 55% da população total. Chegada aos EUA em duas vagas sucessivas - a primeira situada entre 1870 e 1930, a segunda entre 1960 e 1980 - esta comunidade é originária, em cerca de 90% dos casos, do arquipélago dos Açores. Dada esta sua ascendência açoriana, os imigrantes portugueses nos EUA mantêm laços importantes com a cultura do arquipélago, que, como se sabe, ao mesmo tempo que possui bastantes pontes com a cultura portuguesa mais geral, apresenta também inúmeras particularidades.

Involvement of the RNA-binding protein ARE/poly(U)-binding factor 1 (AUF1) in the cytotoxic effects of proinflammatory cytokines on pancreatic beta cells.

AIMS/HYPOTHESIS: Chronic exposure of pancreatic beta cells to proinflammatory cytokines leads to impaired insulin secretion and apoptosis. ARE/poly(U)-binding factor 1 (AUF1) belongs to a protein family that controls mRNA stability and translation by associating with adenosine- and uridine-rich regions of target messengers. We investigated the involvement of AUF1 in cytokine-induced beta cell dysfunction. METHODS: Production and subcellular distribution of AUF1 isoforms were analysed by western blotting. To test for their role in the control of beta cell functions, each isoform was overproduced individually in insulin-secreting cells. The contribution to cytokine-mediated beta cell dysfunction was evaluated by preventing the production of AUF1 isoforms by RNA interference. The effect of AUF1 on the production of potential targets was assessed by western blotting. RESULTS: MIN6 cells and human pancreatic islets were found to produce four AUF1 isoforms (p42>p45>p37>p40). AUF1 isoforms were mainly localised in the nucleus but were partially translocated to the cytoplasm upon exposure of beta cells to cytokines and activation of the ERK pathway. Overproduction of AUF1 did not affect glucose-induced insulin secretion but promoted apoptosis. This effect was associated with a decrease in the production of the anti-apoptotic proteins, B cell leukaemia/lymphoma 2 (BCL2) and myeloid cell leukaemia sequence 1 (MCL1). Silencing of AUF1 isoforms restored the levels of the anti-apoptotic proteins, attenuated the activation of the nuclear factor-κB (NFκB) pathway, and protected the beta cells from cytokine-induced apoptosis. CONCLUSIONS/INTERPRETATION: Our findings point to a contribution of AUF1 to the deleterious effects of cytokines on beta cell functions and suggest a role for this RNA-binding protein in the early phases of type 1 diabetes.