Bayesian versus frequentist statistical inference for investi gating a one-off cancer cluster reported to a health department

Background The problem of silent multiple comparisons is one of the most difficult statistical problems faced by scientists. It is a particular problem for investigating a one-off cancer cluster reported to a health department because any one of hundreds, or possibly thousands, of neighbourhoods, schools, or workplaces could have reported a cluster, which could have been for any one of several types of cancer or any one of several time periods. Methods This paper contrasts the frequentist approach with a Bayesian approach for dealing with silent multiple comparisons in the context of a one-off cluster reported to a health department. Two published cluster investigations were re-analysed using the Dunn-Sidak method to adjust frequentist p-values and confidence intervals for silent multiple comparisons. Bayesian methods were based on the Gamma distribution. Results Bayesian analysis with non-informative priors produced results similar to the frequentist analysis, and suggested that both clusters represented a statistical excess. In the frequentist framework, the statistical significance of both clusters was extremely sensitive to the number of silent multiple comparisons, which can only ever be a subjective "guesstimate". The Bayesian approach is also subjective: whether there is an apparent statistical excess depends on the specified prior. Conclusion In cluster investigations, the frequentist approach is just as subjective as the Bayesian approach, but the Bayesian approach is less ambitious in that it treats the analysis as a synthesis of data and personal judgements (possibly poor ones), rather than objective reality. Bayesian analysis is (arguably) a useful tool to support complicated decision-making, because it makes the uncertainty associated with silent multiple comparisons explicit.

Municipal health department practice for the year 1923, based upon surveys of the 100 largest cities in the United States

At head of title: Treasury Department. United States Public Health Service ...

What does a county health department mean to you?

Cover title.

A directory of the physicians, dentists and druggists of Cincinnati, Covington, Newport, Dayton, Bellevue, and Ludlow : classified according to profession or business, and names arranged, first, in alphabetical order, and, second, according to street or locality ; to which is added lists of medical colleges, hospitals, with names of officers and medical staff of each ; health department, etc., and other valuable information.

Directory section is not illustrated. Illustrated ads for Presbyterian Hospital and Woman's Medical College, Eclectic Medical Institute, and Densmore Typewriter.

Miami-Dade Health Department to Move to Florida International University , Model Clinic to Work with Medical, Public Health and Nursing Faculty

Press Release from Florida International University 's Office of Media Relations on the Miami-Dade Health Department's agreement with Florida International University to relocate its department to Florida International University 's University Park campus.

Department of Energy fiscal year 1983 budget on environment, health, and safety [microform] : hearing before the Subcommittee on Natural Resources, Agriculture Research, and Environment of the Committee on Science and Technology, U.S. House of Representatives, Ninety-seventh Congress, second session, March 11, 1982.

"No. 97."

Department of Mental Health and Developmental Disabilities Act : (20 ILCS 1705/0.01 et seq.)

"Including selected sections of the Civil Administrative Code."

Annual report of the Department of Health of the City of New York ...

1881-1888 never published; statistical report for those years published in the report for 1892.

Weekly report of the Department of Health of the City of New York.

Caption title.

Iowa Department of Public Health Regulatory Plan FY 2016, August 1, 2015

The Department’s vision and mission statements broadly describe the obligations imposed on the Department of Public Health by statute. This plan was approved by Gerd Clabaugh, MPA, Director of the Iowa Department of Public Health. The following table, arranged by Department Divisions, summarizes the administrative rules currently under active consideration or development for fiscal year 2016.

Iowa Department of Public Health, Occupational Health & Safety Surveillance Program Annual Report, July 1, 2013- June 30, 2014, August 1, 2014

The mission of the Iowa OHSSP is to promote and protect the health and safety of Iowans in the workplace. The fundamental or core program provides administrative coordination and continuity across all IDPH OHSSP projects, explores options to improve the surveillance and data translation capacity of the entire program, and provides outreach, dissemination, and evaluation functions to support each project. The core program is also responsible for the Occupational Health Indicators project and Adult Blood Lead Epidemiology and Surveillance (ABLES), as well as working with external partner projects and reports.

Iowa Department of Public Health Maternal and Child Health Administrative Manual 4th Edition, October 23, 2012

The MCH Administrative Manual provides the basis for the development of business practices and programming for maternal and child health services made available through an Iowa Department of Public Health (IDPH) competitive bid process every five years. For each five year project period, policies in the manual provide the basis for the competitive Request for Proposal (RFP). During intervening years, policies provide the basis for the RFP and the Request for Application (RFA) covering the applicable contract year.