Ludwig Levy displaying his sketch pad, showing a drawing of an older man with beard and hat.

Digital Image

Pat Beard

Brock Alumnus Pat Beard was the University Secretary during the 1980's. He was a member of BUSU while a student at Brock.

Pat Beard

Brock Alumnus Pat Beard was the University Secretary during the 1980's. He was a member of BUSU while a student at Brock.

Melle H. Beard Photograph Album - Accession 276 - M119 (152)

The Melle H. Beard Photograph Album collection consists of a photograph album of with images of Winthrop buildings, campus scenes, and pictures of Mrs. Beard and her friends while students at Winthrop College from 1917-1919. Melle Hanahan Beard from Charlotte, NC was a 1919 graduate of Winthrop Normal and Industrial College with an AB degree in Education.

Xenopus Bcl-XL selectively protects Rohon-Beard neurons from metamorphic degeneration

Amphibian metamorphosis involves extensive, but selective, neuronal death and turnover, thus sharing many features with mammalian postnatal development. The antiapoptotic protein Bcl-XL plays an important role in postnatal mammalian neuronal survival. It is therefore of interest that accumulation of the mRNA encoding the Xenopus Bcl-XL homologue, termed xR11, increases abruptly in the nervous system, but not in other tissues, during metamorphosis in Xenopus tadpoles. This observation raises the intriguing possibility that xR11 selectively regulates neuronal survival during postembryonic development. To investigate this hypothesis, we overexpressed xR11 in vivo as a green fluorescent protein (GFP)-xR11 fusion protein by using somatic and germinal transgenesis. Somatic gene transfer showed that the fusion protein was effective in counteracting, in a dose-dependent manner, the proapoptotic effects of coexpressed Bax. When GFP-xR11 was expressed from the neuronal β-tubulin promoter by germinal transgenesis we observed neuronal specific expression that was maintained throughout metamorphosis and beyond, into juvenile and adult stages. Confocal microscopy showed GFP-xR11 to be exclusively localized in the mitochondria. Our findings show that GFP-xR11 significantly prolonged Rohon-Beard neuron survival up to the climax of metamorphosis, even in the regressing tadpole tail, whereas in controls these neurons disappeared in early metamorphosis. However, GFP-xR11 expression did not modify the fate of spinal cord motoneurons. The selective protection of Rohon-Beard neurons reveals cell-specific apoptotic pathways and offers approaches to further analyze programmed neuronal turnover during postembryonic development.

Photograph of a young man with a beard, ca. 1885-1890

Cabinet card featuring the bust of an unidentified young man with a long beard. "Goldsmith ECG 374 Main St. Springfield, Mass" refers to the photography business of Edwin C. Goldsmith. The back of the card is blank.

Blue Beard and, Puss in boots /

Gold cloth binding, with title and design stamped in gilt on front cover; gilt spine title; gilt top edge. Ribbon ties.

Come lo spirito della nostra epoca (Darwin-Nietzsche-Beard) ha concorso all'attuale guerra : riflessioni di un medico napoletano /

Mode of access: Internet.

Holidaymaker satisfaction : a measure derived from the Ragheb and Beard Leisure Motivation Scale

This paper develops a theory of tourist satisfaction which is tested by using a consumerist gap scale derived from the Ragheb and Beard Leisure Motivation Scale. The sample consists of 1127 holiday makers from the East Midlands, UK. The results confirm the four dimensions of the original scale, and are used to develop clusters of holidaymakers. These clusters are found to be determinants of attitudes towards holiday destination attributes, and are independent of socio-demographic variables. Other determinants of holiday maker satisfaction are also examined. Among the conclusions drawn are the continuing importance of life cycle stages and previous holiday maker satisfaction. There is little evidence found for the travel career hypothesis developed by Professor Philip Pearce.