History of the Columbia River Valley from The Dalles to the sea.

Vols. 2-3, biographical.

The papers of Wilbur and Orville Wright, including the Chanute-Wright letters and other papers of Octave Chanute.

"Sponsored by Oberlin College on the Wilbur-Orville Wright Memorial Fund and prepared for the press with notes, appendices, and bibliography by the Aeronautics Division of the Library of Congress."

Linkage disequilibrium mapping in isolated populations: The example of Finland revisited

Linkage disequilibrium analysis can provide high resolution in the mapping of disease genes because it incorporates information on recombinations that have occurred during the entire period from the mutational event to the present. A circumstance particularly favorable for high-resolution mapping is when a single founding mutation segregates in an isolated population. We review here the population structure of Finland in which a small founder population some 100 generations ago has expanded into 5.1 million people today. Among the 30-odd autosomal recessive disorders that are more prevalent in Finland than elsewhere, several appear to have segregated for this entire period in the “panmictic” southern Finnish population. Linkage disequilibrium analysis has allowed precise mapping and determination of genetic distances at the 0.1-cM level in several of these disorders. Estimates of genetic distance have proven accurate, but previous calculations of the confidence intervals were too small because sampling variation was ignored. In the north and east of Finland the population can be viewed as having been “founded” only after 1500. Disease mutations that have undergone such a founding bottleneck only 20 or so generations ago exhibit linkage disequilibrium and haplotype sharing over long genetic distances (5–15 cM). These features have been successfully exploited in the mapping and cloning of many genes. We review the statistical issues of fine mapping by linkage disequilibrium and suggest that improved methodologies may be necessary to map diseases of complex etiology that may have arisen from multiple founding mutations.

Economic conditions of the Virgin Islands. Supplemental report on an investigation of the economic conditions of the Virgin Islands of the United States with special reference to the currency situation and the possibility of establishing an American bank,

Presented by Mr. Willis. Ordered to be printed May 10 (calendar day, May 12), 1926.

Hansische Geschichtsblätter.

Includes "Nachrichten" and "Jahresbericht" of the society; "Hansische Umschau" (a review of contributions to Hanseatic history appearing in other publications) forms a feature of the volumes, beginning with 1920/21.

The book of public speaking /

Mode of access: Internet.

Die Gedankeneinheit des ersten Briefes Petri. Ein Beitrag zur neutestamentlichen Theologie.

Mode of access: Internet.

The library and history study,

Read at the meeting of the Minnesota Educational Assoc., St. Paul, October 23, 1914.

既成政党撲滅論

Mode of access: Internet.

Obras dramàticas /

Binder's title.

The tenting of the Tillicums; a story of boy-life on Puget Sound.

Mode of access: Internet.

American law and procedure /

Mode of access: Internet.

Die Verborgenheit Jesu als des Messias, das Problem des Hebraerbriefes.

Thesis (doctoral)--Greifswald.