The lost trappers; a collection of interesting scenes and events in the Rocky Mountains; together with a short description of California; also, some account of the fur trade, expecially as carried on about the sources of Missouri, Yellow Stone, and on the waters of the Columbia. By David H. Coyner.

Purports to be a narrative, taken from the journal of Ezekiel Williams and other sources, of the wanderings of Willims, James Workman and Samuel Spencer in the western country from 1807 to 1810. The work is called a fabrication by H. M. Chittenden (American fur trade, 1902, v. 2, p. 651-656) It apparently has, however, some foundation in fact. cf. Louis Houck, Hist. of Missouri, 1908, v. 3, p. 93-94.

Increased Activation of Stromal Interaction Molecule-1/Orai-1 in Aorta From Hypertensive Rats A Novel Insight Into Vascular Dysfunction

Disturbances in the regulation of cytosolic calcium (Ca(2+)) concentration play a key role in the vascular dysfunction associated with arterial hypertension. Stromal interaction molecules (STIMs) and Orai proteins represent a novel mechanism to control store-operated Ca(2+) entry. Although STIMs act as Ca(2+) sensors for the intracellular Ca(2+) stores, Orai is the putative pore-forming component of Ca(2+) release-activated Ca(2+) channels at the plasma membrane. We hypothesized that augmented activation of Ca(2+) release-activated Ca(2+)/Orai-1, through enhanced activity of STIM-1, plays a role in increased basal tonus and vascular reactivity in hypertensive animals. Endothelium-denuded aortic rings from Wistar-Kyoto and stroke-prone spontaneously hypertensive rats were used to evaluate contractions because of Ca(2+) influx. Depletion of intracellular Ca(2+) stores, which induces Ca(2+) release-activated Ca(2+) activation, was performed by placing arteries in Ca(2+) free-EGTA buffer. The addition of the Ca(2+) regular buffer produced greater contractions in aortas from stroke-prone spontaneously hypertensive rats versus Wistar-Kyoto rats. Thapsigargin (10 mu mol/L), an inhibitor of the sarcoplasmic reticulum Ca(2+) ATPase, further increased these contractions, especially in stroke-prone spontaneously hypertensive rat aorta. Addition of the Ca(2+) release-activated Ca(2+) channel inhibitors 2-aminoethoxydiphenyl borate (100 mu mol/L) or gadolinium (100 mu mol/L), as well as neutralizing antibodies to STIM-1 or Orai-1, abolished thapsigargin-increased contraction and the differences in spontaneous tone between the groups. Expression of Orai-1 and STIM-1 proteins was increased in aorta from stroke-prone spontaneously hypertensive rats when compared with Wistar-Kyoto rats. These results support the hypothesis that both Orai-1 and STIM-1 contribute to abnormal vascular function in hypertension. Augmented activation of STIM-1/Orai-1 may represent the mechanism that leads to impaired control of intracellular Ca(2+) levels in hypertension. (Hypertension. 2009; 53[part 2]: 409-416.)

Palestine, 1876 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Palestine ancienne & moderne d'après les sources les plus authentiques, par E. Andriveau ; gravé le trait et les montagnes par Gérin, les écritures par P. Rousset, les eaux par Mme Fontaine. It was published by E. Andriveau-Goujon in 1876. Scale 1:600,000. Covers all or portions of Israel, West Bank, Gaza Strip, Jordan, Syria and Lebanon. Map in French with place names in Latin, Arabic and Hebrew. The image inside the map neatline is georeferenced to the surface of the earth and fit to the World Miller Cylindrical projection. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, monasteries, fortification, ruines, territorial boundaries, shoreline features, and more. Relief shown by hachures. Depth shown by sounding and isolines. Includes notes and insets: [Sinai] (Scale [ca. 1:2,600,000]) -- Golfe de Suez -- [Cross section of the Palestine from the source of the Jordan to the Red Sea] -- [Panoramic view of the mountains of Palestine] -- Jérusalem d'après le plan de G. Williams (Scale [ca. 1:80,000]). This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection as part of the Open Collections Program at Harvard University project: Islamic Heritage Project. Maps selected for the project represent a range of regions, originators, ground condition dates, scales, and purposes. The Islamic Heritage Project consists of over 100,000 digitized pages from Harvard's collections of Islamic manuscripts and published materials. Supported by Prince Alwaleed Bin Talal and developed in association with the Prince Alwaleed Bin Talal Islamic Studies Program at Harvard University.

Palestine ancienne & moderne d'après les sources les plus authentiques

par E. Andriveau ; gravé le trait et les montagnes par Gérin, les écritures par P. Rousset, les eaux par Mme Fontaine.

Memoires et voyages ...

Mode of access: Internet.

Storia letteraria della Liguria.

University of Illinois Library bookplate "From the library of Conte Antonio Cavagna Sangiuliani di Gualdana Lazelada di Bereguardo, purchased 1921" on the inside front cover.

Memorials of Columbus; or, A collection of authentic documents of that celebrated navigator, now first published from the original manuscripts, by order of the decurions of Genoa;

Title vignette: "Arms of Columbus after he was created admiral."

A History of the church in seven books : from the accession of Constantine, A.D. 305, to the 38th year of Theodosius II, inluding a period of 140 years /

Mode of access: Internet.

Storia dei santuari più celebri di Maria Santissima : sparsi nel mondo cristiano /

Vol. 5, 1885: Appendice, con biografia del [Antonio Riccardi]

Sallust /

Biographical sketch of Sallust.--History of Catiline's conspiracy.--History of the Jugurthine war.

Lettera al signor preposto Antonio Riccardi di Bergamo in replica alla sua critica polemica sopra le discussioni lauretane.

Mode of access: Internet.

Memoir on the navigation of South America, to accompany a chart of that station.

pt. 1. List of the passages made in H.M.S. Conway, on the South American station, by Captain Basil Hall.--pt. 2. Remarks on the sailing round Cape Horn [April 1814 and March 1815 by] Captain Pipon, on H.M.S. Tagus.

Per la faustissima promozione alla sacra porpora di sua eminenza reverendissima il signor cardinale Agostino Rivarola : poemetto /

Mode of access: Internet.

Voyage dans les États-Unis de l'Amérique du Nord, et dans le Haut et le Bas-Canada,

Translation of: Travels in North America in the years 1827 and 1828.

Voyage au Chili, au Pérou, et an Mexique, pendant les années 1820, 1821 et 1822,

English original, Edinburgh, 1824, pub. under title: Extracts from a journal, written on the coasts of Chili, Peru, and Mexico ...