First explorations of Kentucky : Doctor Thomas Walker's journal of an exploration of Kentucky in 1750, being the first record of a white man's visit to the interior of that territory, now first published entire, with notes and biographical sketch; also Colonel Christopher Gist's journal of a tour through Ohio and Kentucky in 1751, with notes and sketch /

Includes indexes.

[Power of attorney between Stephen Sewall and Thomas Wigglesworth], 1794 August 21

This one-page printed form appoints Thomas Wigglesworth as the "true and lawful Attorney" for Stephen Sewall. The form is notarized by Samuel Barrett and witnessed by Barrett and his daughter Peggy Barrett.

The works of the Reverend Thomas Townson ... : to which is prefixed an account of the author with an introduction to the discourses on the Gospels, and a sermon on the quotations in the Old Testament /

Includes bibliographical references and index.

Comparative susceptibility of mosquito populations in North Queensland, Australia to oral infection with dengue virus

Dengue is the most prevalent arthropod-borne virus, with at least 40% of the world’s population at risk of infection each year. In Australia, dengue is not endemic, but viremic travelers trigger outbreaks involving hundreds of cases. We compared the susceptibility of Aedes aegypti mosquitoes from two geographically isolated populations with two strains of dengue virus serotype 2. We found, interestingly, that mosquitoes from a city with no history of dengue were more susceptible to virus than mosquitoes from an outbreak-prone region, particularly with respect to one dengue strain. These findings suggest recent evolution of population-based differences in vector competence or different historical origins. Future genomic comparisons of these populations could reveal the genetic basis of vector competence and the relative role of selection and stochastic processes in shaping their differences. Lastly, we show the novel finding of a correlation between midgut dengue titer and titer in tissues colonized after dissemination.

Limited dengue virus replication in field-collected Aedes aegypti mosquitoes infected with Wolbachia

Introduction Dengue is one of the most widespread mosquito-borne diseases in the world. The causative agent, dengue virus (DENV), is primarily transmitted by the mosquito Aedes aegypti, a species that has proved difficult to control using conventional methods. The discovery that A. aegypti transinfected with the wMel strain of Wolbachia showed limited DENV replication led to trial field releases of these mosquitoes in Cairns, Australia as a biocontrol strategy for the virus. Methodology/Principal Findings Field collected wMel mosquitoes that were challenged with three DENV serotypes displayed limited rates of body infection, viral replication and dissemination to the head compared to uninfected controls. Rates of dengue infection, replication and dissemination in field wMel mosquitoes were similar to those observed in the original transinfected wMel line that had been maintained in the laboratory. We found that wMel was distributed in similar body tissues in field mosquitoes as in laboratory ones, but, at seven days following blood-feeding, wMel densities increased to a greater extent in field mosquitoes. Conclusions/Significance Our results indicate that virus-blocking is likely to persist in Wolbachia-infected mosquitoes after their release and establishment in wild populations, suggesting that Wolbachia biocontrol may be a successful strategy for reducing dengue transmission in the field.

La autonomía y descentralización del modelo federal venezolano. Una mutación del federalismo dual en el marco del ordenamiento latinoamericano

En la presente investigación se estudió la organización administrativa y territorial de la República Bolivariana de Venezuela, para poder identificar si se podían definir y catalogar a Venezuela como un Estado federal como manda su Constitución, o si por el contrario, podríamos estar hablando de una organización distinta llámese autonómica o unitaria, o simplemente un modelo federal diferente al dual influenciado por las diferentes formas de organización.

Trochoidea elegans in Surrey, England - when did it arrive?

The introduction of the snail Trochoidea elegans to one of its three known sites in Britain has been investigated. 210Pb dating suggests that it has been present at Chaldon, Surrey, at least since the first decade of the twentieth century; it may have been deliberately translocated to this site by the Rev. Canon J. W. Horsley.

The depot for prisoners of war at Norman Cross, Huntingdonshire, 1796 to 1816,

Mode of access: Internet.

[Oeuvres de François Joachim de Pierre, cardinal de Bernis]

Contiene: Discours sur la poesie (p. 1-12), Epitres sur le gout et sur les moeurs (p. 13-42), Poesies diverses (p. 43-52), Reflexions sur les passions et sur les gouts (p. 53-144), Poesies diverses (145-181)