Historiallinen näkökulma maailmanperintökohteiden määrittelyyn

Kirjallisuusarvostelu

Michael Schratz / Johanna F. Schwarz / Tanja Westfall-Greiter: Lernen als bildende Erfahrung, Vignetten in der Praxisforschung, Mit einem Vorwort von Käte Meyer-Drawe und Beiträgen von Horst Rumpf, Carol Ann Tomlinson, Mike Rose u.a. Innsbruck: Studienverlag 2012 [Rezension]

Rezension von: Michael Schratz / Johanna F. Schwarz / Tanja Westfall-Greiter: Lernen als bildende Erfahrung, Vignetten in der Praxisforschung, Mit einem Vorwort von Käte Meyer-Drawe und Beiträgen von Horst Rumpf, Carol Ann Tomlinson, Mike Rose u.a., Innsbruck: Studienverlag 2012 (161 S.; ISBN 978-3706551182)

Human activity recognition for an intelligent knee orthosis

Dissertação para obtenção do Grau de Mestre em Engenharia Biomédica

Kinetics of methanol electrooxidation on PtRu catalysts in a membrane electrode assembly

Methanol oxidation, Kinetics, Mechanism, Rate expression, MEA, PtRu catalysts, Cyclone Flow Cell

Helicobacter pylori-abhängige Regulation der Expression von MMP-1 in humanen Magenepithelzellen

Helicobacter pylori, genexpression, MMP-1, human primary gastric epithelial cells

Community analysis in dynamic social networks

Magdeburg, Univ., Fak. für Informatik, Diss., 2009

CD95-induced apoptosis in health and disease dimers at the DISC and the effect of c-FLIP R on L. Monocytogenes infection

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2013

Kinderarmut und kommunale Armutsprävention

[s.c.]

Pille oder Risiko? : Empirische Belege zum Verhütungsverhalten unter ALG II Bezug

[s.c.]

Low dose endoluminal photodynamic therapy improves murine T cell-mediated colitis.

BACKGROUND AND STUDY AIMS: Low dose photodynamic therapy (LDPDT) may modify the mucosal immune response and may thus provide a therapy for Crohn's disease. We evaluated the efficacy and safety of this technique in a murine T cell-mediated colitis model. METHODS: The safety of LDPDT was first tested in BALB/c mice. Naïve T cells were used to induce colitis in mice with severe combined immunodeficiency, which were followed up endoscopically, and a murine endoscopic index of colitis (MEIC) was developed. The efficacy of LDPDT (10 J/cm (2); delta-aminolevulinic acid, 15 mg/kg bodyweight) was then tested on mice with moderate colitis, while a disease control group received no treatment. The MEIC, weight, length, and histology of the colon, cytokine expression indices, number of mucosal CD4 (+) T cells, percentage of apoptotic CD4 (+) T cells, body weight, and systemic side effects were evaluated. RESULTS: LDPDT improved the MEIC ( P = 0.011) and the histological score ( P = 0.025), diminished the expression indices of the proinflammatory cytokines, interleukin-6 ( P = 0.042), interleukin-17 ( P = 0.029), and interferon-gamma ( P = 0.014), decreased the number of mucosal CD4 (+) T cells, and increased the percentage of apoptotic CD4 (+) T cells compared with the disease control group. No local or systemic side effects occurred. CONCLUSION: LDPDT improves murine T cell-mediated colitis, decreases the proinflammatory cytokines interleukin-6, interleukin-17, and interferon-gamma, and decreases the number of CD4 (+) T cells. No adverse events were observed. Therefore, this technique is now being evaluated in patients with inflammatory bowel disease.