The Littlejohn libel suit : the case of De Witt C. Littlejohn against Horace Greeley : tried at the Oswego term of the Supreme Court of the State of New York, at Pulaski, Sept. 10-13, 1861 ... /

Mode of access: Internet.

Action for libel : report of the case of Angeli v. Galbraith, as tried before the lord chief justice at the Kildare summer assizes, 1856 and before the lord chief baron in the Court of Exchequer, at the after-sittings, Michaelmas term, 1856 /

Errata slip inserted.

Report of the trial of an action on the case, brought by Silvanus Miller, Esq. : late surrogate of the city and county of New-York, against Mordecai M. Noah, Esq. editor of the National advocate, for an alleged libel. Tried at the City-Hall, in the city of New-York, before the Circuit Court held in the First Judicial District in the state of New-York, by His Honour, Samuel R. Betts, Esq. on Friday, the 12th day of December, 1823 /

Not in Rosenbach, A.S.W. Amer. Jewish bib. and supplements.

Review, of the report of the case of the Commonwealth versus David Lee Child, for publishing in the Massachusetts Journal a libel on the honorable John Keyes.

At head of title: (From the Concord (Middlesex) Gazette.).

Trial of the case of the Commonwealth versus David Lee Child, for publishing in the Massachusetts Journal a libel on the Honorable John Keyes : before the Supreme Judicial Court, holden at Cambridge, in the County of Middlesex /

"October term, 1828."

A correct statement and review of the trial of Joseph T. Buckingham for an alledged libel on the Rev. John N. Maffit, before the Hon. Josiah Quincy, judge of the Municipal court, Dec. 16, 1822.

Mode of access: Internet.

A history of the libel suit of Clarence H. Venner against August Belmont : how a plaintiff who had been called a practical blackmailer discontinued his suit for libel when confronted with an order for his examination as to the truth of the charge.

Mode of access: Internet.

Notes on cases in Lennox and Worcester, 1789

Contains notes on cases before the Supreme Court in Lennox and Worcester, Massachusetts relating to counterfeiting, libel, and fraud.

Notes on cases in Boston, 1784-1790

Notes on various cases, including cases of burglary, debt, fraud, libel, receiving stolen goods, and one case of attempted murder of an infant by his mother.

Report of the case of Timothy Upham against Hill & Barton, publishers of the New-Hampshire patriot, for alleged libels, at the Court of common pleas, Rockingham county, March and October terms, 1830.

Mode of access: Internet.

Report of the case John Dorrance against Arthur Fenner, tried at the December term, of the Court of common pleas, in the county of Providence, A.D. 1801; to which are added the proceedings in the case Arthur Fenner vs. John Dorrance.

Mode of access: Internet.

Bridge-street banditti, versus the press : report of the trial of Mary-Anne Carlile, for publishing A New-year's address to the reformers of Great Britain written by Richard Carlile; at the instance of the Constitutional Association, before Mr. Justice Best, and a special jury at the Court of King's Bench, Guildhall, London, July 24, 1821. With the nobel and effectual speech of Mr. Cooper, in defence, at large.

In: The Trials with the defences at large of Mrs. Jane Carlile. London : R. Carlile, 1825.

The triumph of virtue : the trial of Miss Mary Ann Tocker, who plead her own cause, for an alleged libel on R. Gurney, Jun. ... to which is prefixed a letter to Miss Tocker, and to which is added an address to jury-men on their duties as jurors, and especially on trials for criminal libel /

"From the third New-York edition."

Trial of Moore & Sevey for a libel on Samuel D. Greene, in the Municipal Court, Boston, July term, 1833.

Mode of access: Internet.

Predictive Value Of Phase I Trials For Safety In Later Trials And Final Approved Dose: Analysis Of 61 Approved Cancer Drugs.

Phase I trials use a small number of patients to define a maximum tolerated dose (MTD) and the safety of new agents. We compared data from phase I and registration trials to determine whether early trials predicted later safety and final dose. We searched the U.S. Food and Drug Administration (FDA) website for drugs approved in nonpediatric cancers (January 1990-October 2012). The recommended phase II dose (R2PD) and toxicities from phase I were compared with doses and safety in later trials. In 62 of 85 (73%) matched trials, the dose from the later trial was within 20% of the RP2D. In a multivariable analysis, phase I trials of targeted agents were less predictive of the final approved dose (OR, 0.2 for adopting ± 20% of the RP2D for targeted vs. other classes; P = 0.025). Of the 530 clinically relevant toxicities in later trials, 70% (n = 374) were described in phase I. A significant relationship (P = 0.0032) between increasing the number of patients in phase I (up to 60) and the ability to describe future clinically relevant toxicities was observed. Among 28,505 patients in later trials, the death rate that was related to drug was 1.41%. In conclusion, dosing based on phase I trials was associated with a low toxicity-related death rate in later trials. The ability to predict relevant toxicities correlates with the number of patients on the initial phase I trial. The final dose approved was within 20% of the RP2D in 73% of assessed trials.