Cytotoxic lignans from the stems of Styrax camporum (Styracaceae)

An ethanolic extract from the stems of Styrax camporum Pohl (Styracaceae), a plant traditionally used for gastrointestinal diseases, was fractionated and subjected to flash chromatography and afforded two benzofuran lignans, egonol and homoegonol, and one furofuran lignan, (+/-) syringaresinol, which were identified by spectral data interpretation. Their cytotoxic activities against Hep-2 (larynx epidermoid carcinoma), HeLa (human cervix carcinoma) and C6 (rat glioma) cell lines were evaluated using the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide) assay at several concentrations for 24 h. Activities could be observed for egonol against C6 (IC50 = 3.2 mu g/mL) and Hep-2 (IC50 = 3.6 mu g/mL) cell lines, and for homoegonol against C6 (IC50 = 4.9 mu g/mL) and HeLa (IC50 =- 5.3 mu g/mL) cells.

Comparative bark anatomy of root and stem in Styrax camporum (Styracaceae)

The bark of Styrax camporum Pohl (Styracaceae) differs anatomically in the root and stem. Roots have layered secondary phloem; short sieve tubes with simple, transverse or more or less inclined sieve plates; fibres in tangential bands; astrosclereids; wide rays, and a poorly developed periderm. Stems have non-layered secondary phloem; longer sieve tubes with compound, scalariform, inclined sieve plates; sclerified cells and brachyselereids; a developed periderm, and a non-persistent rhytidome. Prismatic crystals, starch grains, phenolic compounds and lipidic contents were observed in root and stem bark cells. The differences between the secondary phloem of root and stem are discussed.

Leaf paraheliotropism in Styrax camporum confers increased light use efficiency and advantageous photosynthetic responses rather than photoprotection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Assessing the role of vertical leaves within the photosynthetic function of Styrax camporum under drought conditions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Triterpenos de Styrax camporum (styracaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leaf heliotropism in Styrax camporum Pohl from the Brazilian cerrado: distinct gas exchange and leaf structure, but similar leaf temperature and water relations

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Morfoanatomia e ontogênese do fruto e semente de Styrax camporum Pohl. (Styracaceae), espécie de cerrado do Estado de São Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Germination of Styrax camporum Pohl. seeds in response to substrate types, moisture contents and the seed morphology

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Comparative wood anatomy of root and stem in Styrax camporum (Styracaceae)

Styrax camporum Pohl is a shrub common in the cerrado vegetation of south-eastern Brazil. Root and stem wood in Styrax camporum differ quantitatively and qualitatively. Quantitative differences follow normal expectations: roots have wider and longer vessel elements, a lower vessel frequency, a lower ray frequency, and wider rays. Qualitative features of the roots are: simple perforation plates, vestured pits, and septate libriform fibres; qualitative features of the stems are: multiple perforation plates, non-vestured pits, and non-septate fibre-tracheids. Based on generally accepted evolutionary trends, root wood of Styrax camporum has more specialized features than stem wood. Additional comparative studies of stem and root anatomy are needed to determine if such differences between root and stem anatomy are widespread, and consistent with the lines of specialization observed in monocotyledons.

Citotoxicidade de Styrax camporum Pohl em macrófagos peritoneais e a liberação de H2O2

The immunological response includes wide contexts involving several cells, and the macrophage is crucial in the cellular immune response. Several stimuli to macrophage membrane may induce the liberation of H2O2, contributing to antibacterial and cytotoxicical actions. Nowadays, there is a tendency to study natural products to verify their capacity of acting in the immune system. This study evaluated the citotoxicity of the bulk extract and the hexanic and acetic fractions extracted from Styrax camporum Pohl (Styracaceae) and the production of H2O2, on murine peritonal macrophages cultures exposed to fractions extracted from this plant. The results showed that the fraction HX 2 mg/ml produced the liberation of H 2O2 in high concentrations and to 4 mg/ml was observed high citotoxicity. The fractions AC did not produce the liberation of H 2O2 and EB was produced in low levels. We conclude that this HX is a potent stimulator of macrophage.

Respostas de trocas gasosas e fluorescência da clorofila A em folhas verticais de Styrax camporum Pohl. (Styracaceae) submetida à deficiência hídrica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Desreplicação dos metabólitos secundários produzidos por Phomopsis stipata, um endófito de Styrax camporum (Styracaceae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Detecção in silico e caracterização estrutural dos constituintes micromoleculares majoritários presentes no fungo endofitico Phomopsis stipata isolado de folhas de Styrax camporum Pohl (Styracaceae) usando CLAE-DAD/EMAR e CG-MS

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo químico e biológico de fungos endofíticos isolados das folhas de Styrax camporum Pohl (Styracaceace)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)