Étude comparative de l'imagerie dans l'évaluation de l'ostéoarthrose du grasset chez le cheval

Les objectifs de cette étude étaient (1) de décrire la localisation et la sévérité des lésions d’ostéoarthrose (OA) chroniques acquises naturellement au niveau du grasset équin grâce à l’échographie (US), la radiographie (XR), la tomodensitométrie (CT) et l’évaluation macroscopique (ME), (2) de comparer la performance diagnostique de chacune des modalities d’imagerie avec ME et (3) d’évaluer quantitativement la densité osseuse sous-chondrale lors d’OA du grasset chez le cheval à la tomodensitométrie. Des évaluations post mortem radiographique, tomodensitométrique et échographique ont été réalisées sur 23 grassets cadavériques et comparées à l’évaluation macroscopique. Des associations significatives ont été notées entre le «osteophytes global score» de toutes les modalités (US, p=0.04; XR, p=0.005; CT, p˂0.0001) et ME. De plus, la tomodensitométrie a démontré la plus forte association. Les ostéophytes étaient principalement localisés au niveau de l’articulation fémorotibiale médiale et cette articulation présentait également les scores d’ostéophytes les plus sévères. Un patron spécifique d’ostéophytes associé à l’insertion de la capsule articulaire sur le condyle fémoral médial a été mis en évidence. La nouvelle projection radiographique (Ca10Pr5L-CrDiMO) a été utile dans la détection des ostéophytes de la région intercondylaire. Les grades d’ostéophytes (0-3) ne différaient pas significativement selon la modalité dans la majorité des sites. La faible sensibilité/spécificité a indiqué que la sclérose de l’os sous-chondral et l’applatissement des condyles fémoraux ne semblent pas être des indicateurs fiables d’OA du grasset équin. L’OA du grasset équin est associée à une réduction de la densité osseuse sous-chondrale et des sites spécifiques de résorption/kystes sous-chondraux ont été notés chez certains spécimens.

How does corruption hurt growth? Evidences about the effects of corruption on factors productivity and per capita income

Corruption is a phenomenon that plagues many countries and, mostly, walks hand in hand with inefficient institutional structures, which reduce the effectiveness of public and private investment. In countries with widespread corruption, for each monetary unit invested, a sizable share is wasted, implying less investment. Corruption can also be a burden on a nation’s wealth and economic growth, by driving away new investment and creating uncertainties regarding private and social rights. Thus, corruption can affect not only factors productivity, but also their accumulation, with detrimental consequences on a society’s social development. This article aims to analyze and measure the influence of corruption on a country’s wealth. It is implicitly admitted that the degree of institutional development has an adverse effect on the productivity of production factors, which implies in reduced per capita income. It is assumed that the level of wealth and economic growth depends on domestic savings, foster technological progress and a proper educational system. Corruption, within this framework, is not unlike an additional cost, which stifles the “effectiveness” of the investment. This article first discusses the key theories evaluating corruption’s economic consequences. Later, it analyzes the relation between institutional development, factor productivity and per capita income, based on the neoclassical approach to economic growth. Finally, it brings some empirical evidence regarding the effects of corruption on factor productivity, in a sample of 81 countries studied in 1998. The chief conclusion is that corruption negatively affects the wealth of a nation by reducing capital productivity, or its effectiveness.

Estabilização extra-articular do joelho com fáscia lata autógena em cães de raças de grande porte

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O centro instantâneo de movimento e vetor velocidade em joelhos submetidos a incisuroplastia troclear e estabilização articular após transecção do ligamento cruzado cranial em cães

Avaliou-se o centro instantâneo de movimento e vetor velocidade após a transecção do ligamento cruzado cranial (LCCr), seguida da substituição ligamentar por retalho de fáscia lata, associada ou não a incisuroplastia troclear (ITR) em nove cães adultos. O joelho direito (GI) foi submetido a ITR e posterior estabilização articular, e o joelho esquerdo submetido somente a substituição ligamentar (GC). Os animais foram avaliados nos períodos pré-operatório, pós-operatório imediato e aos 30, 90 e 180 de pós-operatório, correspondente ao momento de eutanásia de subgrupos de três animais. O centro instantâneo de movimento (CIM) e o vetor velocidade (Vv) resultante foram determinados por meio do deslocamento de pontos a partir da análise radiográfica dos joelhos. Todas as articulações apresentavam CIM e Vv normais antes da transecção do ligamento cruzado cranial. Após a estabilização articular, acompanhada ou não de ITR, observou-se o posicionamento normal do CIM e Vv resultante, em todos os períodos de avaliação, apesar da presença de movimento de gaveta em três animais de GC e dois de GI no pós-operatório imediato, em dois animais de cada grupo, aos 30 dias de avaliação, e em um animal em cada grupo nas avaliações subseqüentes. Conclui-se que a estabilização articular com retalho de fáscia lata, associada ou não a ITR, mantém a integridade biomecânica do joelho, quando considerados o CIM e o Vv.

Transposição e avanço da tuberosidade tibial para tratamento da luxação medial de patela associada à ruptura do ligamento cruzado cranial em cães: estudo clínico

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Anormalidades ultrassonográficas e radiográficas em joelhos de cavalos da raça Quarto de Milha da linhagem de apartação

Pós-graduação em Medicina Veterinária - FMVZ

Effect of lateral meniscectomy and osteochondral grafting of a lateral femoral condylar defect on contact mechanics: a cadaveric study in dogs

BACKGROUND Osteochondral autograft transfer (OAT) aims at restoring normal articular cartilage surface geometry and articular contact mechanics. To date, no studies have evaluated the contact mechanics of the canine stifle following OAT. Additionally, there are no studies that evaluated the role of the meniscus in contact mechanics following OAT in human or canine femorotibial joints. The objective of this study was to measure the changes in femorotibial contact areas (CA), mean contact pressure (MCP) and peak contact pressure (PCP) before and after osteochondral autograft transplantation (OAT) of a simulated lateral femoral condylar cartilage defect with an intact lateral meniscus and following lateral meniscectomy. RESULTS With an intact lateral meniscus, creation of an osteochondral defect caused a decrease in MCP and PCP by 11% and 30%, respectively, compared to the intact stifle (p < 0.01). With an intact meniscus, implanting an osteochondral graft restored MCP and PCP to 96% (p = 0.56) and 92% (p = 0.41) of the control values. Lateral meniscectomy with grafting decreased CA by 54% and increased PCP by 79% compared to the intact stifle (p < 0.01). CONCLUSIONS OAT restored contact pressures in stifles with a simulated lateral condylar defect when the meniscus was intact. The lateral meniscus has a significant role in maintaining normal contact pressures in both stifles with a defect or following OAT. Meniscectomy should be avoided when a femoral condylar defect is present and when performing OAT.

Effects of early intensive postoperative physiotherapy on limb function after tibial plateau leveling osteotomy in dogs with deficiency of the cranial cruciate ligament

Objective-To determine effects of early intensive postoperative physiotherapy on limb function in dogs after tibial plateau leveling osteotomy (TPLO) for deficiency of the cranial cruciate ligament (CCL). Animals-8 adult dogs with CCL deficiency. Procedure-After TPLO, dogs underwent a physiotherapy program 3 times/wk (physiotherapy group; n = 4) or a walking program (home-exercise group; 4). All dogs were evaluated before surgery, 1 and 10 days after surgery, and 3 and 6 weeks after surgery. Thigh circumference (TC), stifle joint flexion and extension range of motion (ROM), lameness, and weight-bearing scores were recorded. Results-Before surgery, CCL-deficient limbs had significantly reduced TC and reduced flexion and extension ROMs, compared with values for the contralateral control limb. Six weeks after TPLO, the physiotherapy group had significantly larger TC than the home-exercise group, with the difference no longer evident between the affected and nonaffected limbs. Extension and flexion ROMs were significantly greater in the physiotherapy group, compared with values for the home-exercise group, 3 and 6 weeks after surgery. Six weeks after surgery, the difference in flexion and extension ROMs was no longer evident between the affected and nonaffected limbs in the physiotherapy group. Both groups had improvements for lameness and weight-bearing scores over time, but no difference was found between the 2 groups. Conclusions and Clinical Relevance-After TPLO in CCL-deficient dogs, early physiotherapy intervention should be considered as part of the postoperative management to prevent muscle atrophy, build muscle mass and strength, and increase stifle joint flexion and extension ROMs.

Driven entrepreneurial education in vocational schools

Vocational Education and Training (VET) is offered throughout the world to students of various educational backgrounds and career aspirations in an effort to create a skilled workforce. The structure of VET varies greatly across different fields and countries with high-growth, low-growth, and transitional economies. However, a common critique of many vocational institutions is that they focus on skills training without addressing related business systems. Thus, students may not understand the business strategies related to their field, which stifles job readiness and entrepreneurial potential. To counter this, a more context-driven and integrated entrepreneurial approach is proposed for VET. Benefits, disadvantages, and exemplars of various types of vocational and entrepreneurial programs are evaluated to determine how their strengths might be leveraged. Such integrated entrepreneurial and vocational training would more suitably address context-specific market needs via both practical and transferrable skills, thus helping to reduce unemployment, particularly among youth in sub-Saharan Africa. (DIPF/Orig.)