968 resultados para Shannon, Daniel


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Lt. Daniel Shannon fl. 1777-1822, was the only son of Susan Drake, granddaughter of Rev. Thomas Drake, eldest brother of Sir Francis Drake, and Captain Daniel Shannon of the Royal Navy. He married Elizabeth Garvey, daughter of Alexander Garvey and Catharine Borden of New Jersey. Lt. Shannon was a Regular in the British Army and on February 12, 1777 he joined the Royal Standard, 5th New Jersey Volunteers. After being arrested and sentenced to hang for spying he was pardoned through the efforts of his mother Susan Drake Shannon who pleaded his case with the Governor. He served under General Cornwallis at the surrender in Virginia in 1781. In 1783 he moved to New Brunswick, Canada where he was reduced to a half-pay ensign in the 2nd Regiment of the Lincoln Militia. He was granted 500 acres of land on the St. Johns River, and on April 1, 1786 his daughter Catharine was born there. The family returned to the United States, residing in Pennsylvania, for a short time. In 1800 Lt. Shannon, with his mother and family, returned to Canada and settled in Stamford Township where he bought 200 acres of land on the Niagara River near the whirlpool. He later served in the Secret Service during the War of 1812 and was stationed at a lookout point on the Niagara River below the falls. In 1806 Shannon’s daughter, Catharine, married Thomas Lundy, fourth son of William Lundy of Stamford Township.

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A letter regarding an affidavit discussing the half pay of Daniel Shannon from the 25th June to the 21st of December 1819.

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An oath by Daniel Shannon concerning his employment from the 25th of June to the 24th of December 1820.

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An affidavit confirming that Daniel Shannon resided in the province and fulfilled loyal service in the War of 1812 as a look out in the Niagara Region. It is signed by Thomas Clark and Thomas Dickson of the 2nd Regiment of the Lincoln Militia.

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A letter stating that Military Half Pay would from then on be paid from the Commissariat Office. As a result, they require a new letter of attorney. It also states the half pay amount of Daniel Shannon.

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Grandiflora: Recent Paintings by Daniel Mafe The paintings of Grandiflora are improvised around a range of different flower motifs culled from medieval textiles and botanical illustrations. Each of the paintings is constructed upon a ground of flat, palely luminous yellow occasionally supplemented by additional areas of high-keyed pastel. Pink, blue, green and mauve together with the yellow, generate a shimmering and even incandescent glow. The graphic images of the flowers with the flat colour areas are then contrasted and worked over with richly sensual, abstract gestures of paint. Within the work there is a pronounced almost rococo-esque opticality as it operates between these different visual codes of flat colour, recognizable floral forms, and gesture. These codes combine to produce a definite visceral impact on the viewer, a pronounced and tactile sense of the experience and ambiguity inherent in perceiving. This ambiguity is interestingly at odds with the apparently clean and crisp quality each painting demonstrates as an integrated whole. Indeed each piece goes on to reveal, despite the use of overt figurative quotations, a sense of the purely abstract which in its turn concretely establishes the ornamental.

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Normanton2020 This exhibition showcases the work of 3rd -4th year undergraduate landscape architecture, architecture, Interior Design, Environmental Engineering, Civil Engineering students in response to issues of sustainability in the Gulf of Carpentaria town of Normanton. 16 students and four staff set off on a 2488km journey to undertake the second half of the Carpentaria Project (following Linking Karumba: Creating Sustainable Connections 2008), in the other Carpentaria Shire town of Normanton. This project, Get EnGulfed: Normanton 2020, looked back and forwards to propose strategies strengthening local and regional identities. Our project partners recognised the need for a strategic approach to developing future visions for Normanton’s growth as a socially, culturally, economically and ecologically sustainable town in the decade to 2020. They proposed: Project aims to foster: • Enhanced liveability; • A strengthened expression of town identity; • Expanded sustainable tourism. Primary challenges & opportunities: • Remoteness; • Two seasons: wet & dry; • Local economy; • Society and Cultural Heritage. The Exhibition Four groups of four students produced four strategic planning and design options toward this future: Mud Maps of Normanton: Rhys Belnap, AJ Humphries, Amos Shirreff, Haiku Van Keuk Normanton: Stay Another Day: Belle Dalton, Tom Jordan, Josh Nielsen, Carla Ramsland The Sweet Spot on the Savannah Way: Daniel Lapham, Yvonne Phillips, Patrick Poon, Dan Young Resilience Through Diversity: Jillian Kenny, Tania Metcher, Stephen Orr, Evan Thompson

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Get EnGulfed: Normanton2020 This exhibition showcases the work of 3rd -4th year undergraduate landscape architecture, architecture, Interior Design, Environmental Engineering, Civil Engineering students in response to issues of sustainability in the Gulf of Carpentaria town of Normanton. It presented the work to QUT staff from across the university, as well as industry partners and invited guests. 16 students and four staff set off on a 2488km journey to undertake the second half of the Carpentaria Project (following Linking Karumba: Creating Sustainable Connections 2008), in the other Carpentaria Shire town of Normanton. This project, Get EnGulfed: Normanton 2020, looked back and forwards to propose strategies strengthening local and regional identities. Our project partners recognised the need for a strategic approach to developing future visions for Normanton’s growth as a socially, culturally, economically and ecologically sustainable town in the decade to 2020. They proposed: Project aims to foster: • Enhanced liveability; • A strengthened expression of town identity; • Expanded sustainable tourism. • Primary challenges & opportunities: • Remoteness; • Two seasons: wet & dry; • Local economy; • Society and Cultural Heritage. The Exhibition Four groups of four students produced four strategic planning and design options toward this future: Mud Maps of Normanton: Rhys Belnap, AJ Humphries, Amos Shirreff, Haiku Van Keuk Normanton: Stay Another Day: Belle Dalton, Tom Jordan, Josh Nielsen, Carla Ramsland The Sweet Spot on the Savannah Way: Daniel Lapham, Yvonne Phillips, Patrick Poon, Dan Young Resilience Through Diversity: Jillian Kenny, Tania Metcher, Stephen Orr, Evan Thompson

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Genome-wide association studies (GWAS) have identified 76 variants associated with prostate cancer risk predominantly in populations of European ancestry. To identify additional susceptibility loci for this common cancer, we conducted a meta-analysis of > 10 million SNPs in 43,303 prostate cancer cases and 43,737 controls from studies in populations of European, African, Japanese and Latino ancestry. Twenty-three new susceptibility loci were identified at association P < 5 × 10(-8); 15 variants were identified among men of European ancestry, 7 were identified in multi-ancestry analyses and 1 was associated with early-onset prostate cancer. These 23 variants, in combination with known prostate cancer risk variants, explain 33% of the familial risk for this disease in European-ancestry populations. These findings provide new regions for investigation into the pathogenesis of prostate cancer and demonstrate the usefulness of combining ancestrally diverse populations to discover risk loci for disease.

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Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same region.

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Tutkielma käsittelee Bo Carpelanin romaania Alkutuuli (Urwind 1993) päähenkilö Daniel Urwindin fragmentaarisesti kerrottuna elämäntarinana. Kyse on kahdella aikatasolla etenevästä fiktiivisestä omaelämäkerrasta, joka perustuu viikottaisiin päiväkirjamerkintöihin. Daniel hahmottaa identiteettiään tilaan kytkeytyneiden muistojen sekä oman nimensä avulla leikaten samalla kerronnan jatkuvuuden. Tutkimusongelmana on hahmottaa Danielin kerronnan tavat, kirjoittamisen syyt sekä prosessiin lopputulos. Menneisyyteen kohdistuvan minä-kerronnan analyysi perustuu Dorrit Cohnin Transparent minds -teoksen käsitteistöön. Alkutuulessa esiintyy muistikerronnan ja muistimonologin epäsäännöllistä vuorottelua. Niiden osana on edesmenneiden läheisten upotettuja monologeja, joiden takaa kuultaa Danielin ääni: monologit ovat Danielin kuvittelemia tai referoimia puheita ja ajatuksia, joiden esittäjä on hänen yksinäisen keskustelunsa toinen osapuoli. Omaelämäkertaa käsittelevinä teoreettisina lähteinä ovat ensisijaisesti Päivi Kososen artikkelit sekä hänen tutkimuksensa Elämät sanoissa. Tutkielman tulkinnan kannalta keskeisessä asemassa ovat Bo Carpelanin essee- ja kaunokirjallinen tuotanto. Kirjoittamisen lähtökohtana on päähenkilön identiteettiä horjuttava elämänvaihe. Vaimo Marian lähdettyä vuodeksi Amerikkaan Daniel pyrkii löytämään oman kielensä ja luomaan muistojensa avulla eheämmän kuvan itsestään. Prosessiin kytkeytyy keskeisesti tila - Danielin kulkiessa talossaan, joka on hänen lapsuudenkotinsa, aistitodellisuus toimii mieleenpalauttajana: äänet ja tuoksut johdattavat hänet elämään menneisyyden muistoja uudelleen nykyhetkessä. Samalla talo ja huoneet personifioituvat ja minuus alkaa rakentua tilan kaltaiseksi. Uusien ovien ja huoneiden löytyminen symboloi Danielin muistojen selkeytymistä ja itseymmärryksen syvenemistä. Kirjoittamisen voi tulkita olevan psykoanalyyttinen prosessi, jossa omaelämäkerran minä keskustelee menneisyyden minänsä kanssa. Puhuja odottaa vastausta toiselta, vaikka vastaus löytyy paradoksaalisesti itsestä. Omaelämäkerran moniäänisyyttä korostavat edesmenneiden läheisten läsnäolo, Danielin eri ikävaiheiden identiteetit ja kaksoisolentojen hahmoissa esiintyvät minuudet. Kirjoittamisen avulla Daniel pyrkii pääsemään etäämmälle itsestään ja saavuttamaan minättömyyden tilan, jota käsitellään John Keatsilta peräisin olevan käsitteen "negatiivinen kyky" avulla. Alkutuuli on taiteilijaromaani, jossa taiteilijuutta edustavat siivet ja lentäminen kytkeytyvät mielikuvitukseen ja uusiutumiseen. Danielin tie taiteilijuutta edeltävään minättömyyteen on kuitenkin vaikea ja monet merkit viittaavat diletantin kohtaloon. Unenomaisen logiikan omaavan, fragmentaarisen kerronnan takaa on hahmotettavissa myös lainalaisuuksia. Muiden henkilöiden lyhyet elämäkerrat ovat heidän haavansa paljastavia episodeja, jotka muuttuvat osaksi Danielin elämäntarinaa. Danielin kirjallinen omakuva on montaasi, jossa eri tasossa olevat elementit, nykyhetki ja menneisyys, mielikuvitus, unet ja upotetut monologit rinnastuvat samaan tasoon. Daniel peilaa elettyä ja koettua koomisen peilirakenteen avulla, jossa hänen elämäänsä osallisena olleet menneisyyden henkilöt kulkevat narrikulkueen mukana. Toive eheästä minäkuvasta osoittautuu kuitenkin mahdottomaksi merkityssulkeuman todenvastaisuuden vuoksi. Urwind-nimen pohdinnasta liikkeelle lähtenyt omaelämäkerta päättyy syklistä liikettä mukaillen tilanteeseen, jossa päähenkilö hyväksyy elämän käsittämättömyyden ja luottaa omassa nimessään piilevään voimaan, tuuleen, viitaten samalla myös romaanin nimeen. Avainsanat: Bo Carpelan - muistot - tila - fragmentaarisuus - fiktiivinen omaelämäkerta