119 resultados para Seierstad, Åsne


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Kirjallisuutta

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Mode of access: Internet.

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At head of title: Jiří Karásek ze Lvovic.

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Czech, German, and Latin.

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Contains music.

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Mode of access: Internet.

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Mode of access: Internet.

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In this Letter, we propose a new and model-independent cosmological test for the distance-duality (DD) relation, eta = D(L)(z)(1 + z)(-2)/D(A)(z) = 1, where D(L) and D(A) are, respectively, the luminosity and angular diameter distances. For D(L) we consider two sub-samples of Type Ia supernovae (SNe Ia) taken from Constitution data whereas D(A) distances are provided by two samples of galaxy clusters compiled by De Filippis et al. and Bonamente et al. by combining Sunyaev-Zeldovich effect and X-ray surface brightness. The SNe Ia redshifts of each sub-sample were carefully chosen to coincide with the ones of the associated galaxy cluster sample (Delta z < 0.005), thereby allowing a direct test of the DD relation. Since for very low redshifts, D(A)(z) approximate to D(L)(z), we have tested the DD relation by assuming that. is a function of the redshift parameterized by two different expressions: eta(z) = 1 + eta(0)z and eta(z) = 1 +eta(0)z/(1 + z), where eta(0) is a constant parameter quantifying a possible departure from the strict validity of the reciprocity relation (eta(0) = 0). In the best scenario (linear parameterization), we obtain eta(0) = -0.28(-0.44)(+0.44) (2 sigma, statistical + systematic errors) for the De Filippis et al. sample (elliptical geometry), a result only marginally compatible with the DD relation. However, for the Bonamente et al. sample (spherical geometry) the constraint is eta(0) = -0.42(-0.34)(+0.34) (3 sigma, statistical + systematic errors), which is clearly incompatible with the duality-distance relation.

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We discuss the properties of homogeneous and isotropic flat cosmologies in which the present accelerating stage is powered only by the gravitationally induced creation of cold dark matter (CCDM) particles (Omega(m) = 1). For some matter creation rates proposed in the literature, we show that the main cosmological functions such as the scale factor of the universe, the Hubble expansion rate, the growth factor, and the cluster formation rate are analytically defined. The best CCDM scenario has only one free parameter and our joint analysis involving baryonic acoustic oscillations + cosmic microwave background (CMB) + SNe Ia data yields (Omega) over tilde = 0.28 +/- 0.01 (1 sigma), where (Omega) over tilde (m) is the observed matter density parameter. In particular, this implies that the model has no dark energy but the part of the matter that is effectively clustering is in good agreement with the latest determinations from the large- scale structure. The growth of perturbation and the formation of galaxy clusters in such scenarios are also investigated. Despite the fact that both scenarios may share the same Hubble expansion, we find that matter creation cosmologies predict stronger small scale dynamics which implies a faster growth rate of perturbations with respect to the usual Lambda CDM cosmology. Such results point to the possibility of a crucial observational test confronting CCDM with Lambda CDM scenarios through a more detailed analysis involving CMB, weak lensing, as well as the large-scale structure.

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NGC 1275, the central galaxy in the Perseus cluster, is the host of gigantic hot bipolar bubbles inflated by active galactic nucleus (AGN) jets observed in the radio as Perseus A. It presents a spectacular H alpha-emitting nebulosity surrounding NGC 1275, with loops and filaments of gas extending to over 50 kpc. The origin of the filaments is still unknown, but probably correlates with the mechanism responsible for the giant buoyant bubbles. We present 2.5 and three-dimensional magnetohydrodynamical (MHD) simulations of the central region of the cluster in which turbulent energy, possibly triggered by star formation and supernovae (SNe) explosions, is introduced. The simulations reveal that the turbulence injected by massive stars could be responsible for the nearly isotropic distribution of filaments and loops that drag magnetic fields upward as indicated by recent observations. Weak shell-like shock fronts propagating into the intracluster medium (ICM) with velocities of 100-500 km s(-1) are found, also resembling the observations. The isotropic outflow momentum of the turbulence slows the infall of the ICM, thus limiting further starburst activity in NGC 1275. As the turbulence is subsonic over most of the simulated volume, the turbulent kinetic energy is not efficiently converted into heat and additional heating is required to suppress the cooling flow at the core of the cluster. Simulations combining the MHD turbulence with the AGN outflow can reproduce the temperature radial profile observed around NGC 1275. While the AGN mechanism is the main heating source, the SNe are crucial to isotropize the energy distribution.

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A acetilcolina (ACh) é o neurotransmissor mais importante no controlo da motilidade gastrointestinal. A libertação de ACh dos neurónios entéricos é regulada por receptores neuronais específicos (De Man et al., 2003). Estudos prévios demonstraram que a adenosina exerce um papel duplo na libertação de ACh dos neurónios entéricos através da activação dos receptores inibitórios A1 e facilitatórios A2A (Duarte-Araújo et al., 2004). O potencial terapêutico dos compostos relacionados com a adenosina no controlo da motilidade e da inflamação intestinal, levou-nos a investigar o papel dos receptores com baixa afinidade para a adenosina, A2B e A3, na libertação de acetilcolina induzida por estimulação eléctrica nos neurónios mioentéricos. Estudos de imunolocalização mostraram que os receptores A2B exibem um padrão de distribuição semelhante ao do marcador de células gliais (GFAP). No que respeita aos receptores A1 e A3, estes encontram-se distribuídos principalmente nos corpos celulares dos neurónios ganglionares mioentéricos, enquanto os receptores A2A estão localizados predominantemente nos terminais nervosos colinérgicos. Neste trabalho mostrou-se que a modulação da libertação de ACh-[3H] (usando os antagonistas selectivos DPCPX, ZM241385 e MRS1191) é balanceada através da activação tónica dos receptores inibitórios (A1) e facilitatórios (A2A e A3) pela adenosina endógena. O antagonista selectivo dos receptores A2B, PSB603, não foi capaz de modificar o efeito inibitório da NECA (análogo da adenosina com afinidade para receptores A2). O efeito facilitatório do agonista dos receptores A3, 2-Cl-IB MECA (1-10 nM), foi atenuado pelo MRS1191 e pelo ZM241385, os quais bloqueiam respectivamente os receptores A3 e A2A. Contrariamente à 2-Cl-IB MECA, a activação dos receptores A2A pelo CGS21680C, atenuou a facilitação da libertação de ACh induzida pela activação dos receptores nicotínicos numa situação em que a geração do potencial de acção neuronal foi bloqueada pela tetrodotoxina. A localização diferencial dos receptores excitatórios A3 e A2A ao longo dos neurónios mioentéricos explica porque razão a estimulação dos receptores A3 (com 2-Cl-IB MECA) localizados nos corpos celulares dos neurónios mioentéricos exerce um efeito sinérgico com os receptores facilitatórios A2A dos terminais nervosos no sentido de aumentarem a libertação de ACh. Os resultados apresentados consolidam e expandem a compreensão actual da distribuição e função dos receptores da adenosina no plexo mioentérico do íleo de rato, e devem ser tidos em consideração para a interpretação de dados relativos às implicações fisiopatológicas da adenosina nos transtornos da motilidade intestinal.

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Rift Valley fever (RVF) is a mosquito-borne viral disease which manifested itself during recent epidemics and revealed its significant potential of emergence. Studies on molecular epidemiology undertaken to better understand the factors leading to RVF emergence, have confirmed the mode of circulation of the virus and highlithted probable risks and obstacles for prevention and control. As for several other viral agents, molecular epidemiology is becoming a useful tool in the study of the emergence of RVF as a serious infectious disease.

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The construction of the Diama dam on the Senegal river, the Manantali dam on the Bafing river, Mali and the ensuing ecological changes have led to a massive outbreak of Schistosoma mansoni in Northern Senegal, associated with high intensity of infections, due to intense transmission, and the creation of new foci of S. haematobium. Data on the vectorial capacity of Biomphalaria pfeifferi from Ndombo, near Richard Toll, Senegal are presented with sympatric and allopatric (Cameroon) S. mansoni. Comparisons are made on infectivity, cercarial production, chronobiology of cercarial emergence and longevity of infected snails. Recent data on the intermediate host specificity of different isolates of S. haematobium from the Lower and Middle Valley of the Senegal river basin (SRB) demonstrate the existence of at least two strains of S. haematobium. The role of Bulinus truncatus in the transmission of S. haematobium in the Lower and Middle Valleys of the SRB is reviewed. Both S. haematobium and S. mansoni are transmitted in the same foci in some areas of the SRB.