The constant captain, Gonzalo de Sandoval.

Includes bibliography.

Sacrae ecclesiae orationes : (quas vulgo collectas vocamus) & hybernae & aestiuae partiu[m] ta[m] de tempore q[uam] de sanctis, cu[m] no[n]nullis conclusionu[m] regulis, ex probatissimis diuinor[um] officiorum codicibus atte[n]tis no[n] minus orthographia

Capitulares grab. xil.

Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping

Proteomic and transcriptomic platforms both play important roles in cancer research, with differing strengths and limitations. Here, we describe a proteo-transcriptomic integrative strategy for discovering novel cancer biomarkers, combining the direct visualization of differentially expressed proteins with the high-throughput scale of gene expression profiling. Using breast cancer as a case example, we generated comprehensive two-dimensional electrophoresis (2DE)/mass spectrometry (MS) proteomic maps of cancer (MCF-7 and HCC-38) and control (CCD-1059Sk) cell lines, identifying 1724 expressed protein spots representing 484 different protein species. The differentially expressed cell-line proteins were then mapped to mRNA transcript databases of cancer cell lines and primary breast tumors to identify candidate biomarkers that were concordantly expressed at the gene expression level. Of the top nine selected biomarker candidates, we reidentified ANX1, a protein previously reported to be differentially expressed in breast cancers and normal tissues, and validated three other novel candidates, CRAB, 6PGL, and CAZ2, as differentially expressed proteins by immunohistochemistry on breast tissue microarrays. In total, close to half (4/9) of our protein biomarker candidates were successfully validated. Our study thus illustrates how the systematic integration of proteomic and transcriptomic data from both cell line and primary tissue samples can prove advantageous for accelerating cancer biomarker discovery.

Prouerbios de Seneca.

Capitulares grab. xil.

Rituum ecclesiasticorum siue Sacrarum cerimoniarum S.S. Romanæ Ecclesiæ libri tres non ante impressi.

Pie de imp. tomado del colofón

Liber theoricae necnon practicae Alsaharauii in prisco Arabum Medicorum conuentu facile principis qui vulgo Açararius dicitur.

Iam summa diligentia & cura depromptus in lucem

Sermones quadragesimales / fratris Antonii de vercellis de XII mirabilibus christiane fidei excellentiis.

Sign.: a-z8, [et]8, [cum]8, [rum]8, A-G8, j4

Opuscula / Sancti Thome ; quibus alias impressis nuper hec addidimus, v[idelic]et Summa[m] totius logice, Tractatum celeberrimum de vsuris nusq[uam] alias impressum.

Pie de imp. tomado del colofón en 2P7v

Luciani Opuscula / Erasmo Roterodamo interprete ... Eiusdem Luciani Thoma Moro interprete ... Eiusdem Thomae Mori, De optimo Reip. statu deq[ue] noua insula Vtopia libellus vere aureus.

Sign.: a-z8, [et] 8, [cum]8, [rum]8, A-I8, K4

Libro della prima guerra delli Carthaginesi con li Romani / composto da Misser Leonardo Aretino ; fatto vvlgare da vno suo amico ; [et] nuouamente stampato.

Huecos para iniciales con letras de aviso

Libro della guerra de Ghotti / composto da Misser Leonardo Aretino in lingua latina ; et fatto vvlgare da Lodouico Petroni caualiere senese ; nuouamente stampato.

Huecos para iniciales con letras de aviso

Prouerbios de Seneca.

Menéndez Pelayo atribuye la glosa de los proverbios a Pedro Díaz de Toledo

Libro della prima guerra delli Carthaginesi con li Romani / composto da Misser Leonardo Aretino ; fatto vvlgare da vno suo amico ; [et] nuouamente stampato.

Huecos para iniciales con letras de aviso

Libro della guerra de Ghotti / composto da Misser Leonardo Aretino in lingua latina ; et fatto vvlgare da Lodouico Petroni caualiere senese ; nuouamente stampato.

Huecos para iniciales con letras de aviso

Prouerbios de Seneca.

Menéndez Pelayo atribuye la glosa de los proverbios a Pedro Díaz de Toledo