The European Hematology Association Roadmap for European Hematology Research: a consensus document

Abstract The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at Euro 23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine sections in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients. Received December 15, 2015. Accepted January 27, 2016. Copyright © 2016, Ferrata Storti Foundation

Research activities of Spanish antenna groups

When we look at the history of electricity and electromagnetism in Spain we discover that the most important Spanish researchers are generally out of the official institutions or stable research groups until the 20th century [1] [2]. In the 20th century most of the scientific research is done in stable research institutions and universities and the most important electromagnetism research centres in Spain are located in the Faculty of Physics of the most important universities, the National Scientific Research Council (CSIC) and the School for Telecommunication Engineering created in 1923. But the greatest impulse of research in the antenna and radiowave propagation field is done after 1960 reaching the first national URSI conference in 1980. After that year, the relation between groups and the number of research groups is continuously growing and the relation to industry is also increasing. When Spain joins the European research organizations (COST, ERC...) and the European Union in 1985 the research support experience a fast growing and the participation in the European research structures. In the antenna design field, there exist some specializations although most of the groups have dome specific projects in almost all the antenna analysis and design fields. Here, we have selected the most important and characteristic area related to each of the research groups and institutions. The easiest way to classify the research work in antennas is the selection between antenna analysis, design and measurement. After that the selected frequency bands technology, the type of antennas and the related circuits can be a good criterion to describe the variety of research work and specialization between groups.

How does innovation happen in the upstream oil & gas industry? Insights from a global survey

Few would argue that the upstream oil & gas industry has become more technology-intensive over the years. But how does innovation happen in the industry? Specifically, what ideas and inputs flow from which parts of the sector’s value network, and where do these inputs go? And how do firms and organizations from different countries contribute differently to this process? This paper puts forward the results of a survey designed to shed light on these issues. A joint research initiative between the Society of Petroleum Engineers and the Queensland University of Technology, the survey was sent to 469 executives and senior managers who played a significant role with regards to R&D and/or technology deployment in their respective business units. A total of 199 responses were received from a broad range of organizations and countries around the world. Several interesting themes and trends emerge from the results, including: (1) service companies tend to file considerably more patents per innovation than other types of organization; (2) over 63% of the deployed innovations reported in the survey originated in service companies; (3) neither universities nor government-led research organizations are considered to be valuable sources of new information and knowledge in the industry’s R&D initiatives; and (4) despite the increasing degree of globalization in the marketplace, the USA still plays an extremely dominant role in the industry’s overall R&D and technology deployment activities. By providing a detailed snapshot of how innovation happens in the upstream oil & gas sector, this paper provides a valuable foundation for future investigations and discussions aimed at improving how R&D and technology deployment are managed within the industry.

How innovation and R&D happen in the upstream oil & gas industry : insights from a global survey

Few would disagree that the upstream oil & gas industry has become more technology-intensive over the years. But how does innovation happen in the industry? Specifically, what ideas and inputs flow from which parts of the sector׳s value network, and where do these inputs go? And how do firms and organizations from different countries contribute differently to this process? This paper puts forward the results of a survey designed to shed light on these questions. Carried out in collaboration with the Society of Petroleum Engineers (SPE), the survey was sent to 469 executives and senior managers who played a significant role with regard to R&D and/or technology deployment in their respective business units. A total of 199 responses were received from a broad range of organizations and countries around the world. Several interesting themes and trends emerge from the results, including: (1) service companies tend to file considerably more patents per innovation than other types of organization; (2) over 63% of the deployed innovations reported in the survey originated in service companies; (3) neither universities nor government-led research organizations were considered to be valuable sources of new information and knowledge in the industry׳s R&D initiatives, and; (4) despite the increasing degree of globalization in the marketplace, the USA still plays an extremely dominant role in the industry׳s overall R&D and technology deployment activities. By providing a detailed and objective snapshot of how innovation happens in the upstream oil & gas sector, this paper provides a valuable foundation for future investigations and discussions aimed at improving how R&D and technology deployment are managed within the industry. The methodology did result in a coverage bias within the survey, however, and the limitations arising from this are explored.

Informazio-iturrien garrantzia berrikuntza teknologikoko jardueretarako

[EU]Gaur egunean bizi dugun krisi ekonomiko, produkzio ereduen transformazio eta globalizazioko testuinguruan, ikerketa, garapena eta berrikuntza (I+G+b) ezinbesteko faktoreak bilakatu dira herrialdeen hazkunde eta enpresen lidergo zein biziraupenerako. Berritasunaren bilatze horretan, egungo merkatuan enpresek etengabe egin beharreko egokitzapen teknologikoak direla eta, berrikuntza teknologikoak, hau da, produktuan edo prozesuan berritzeak, berebiziko garrantzia du. Gainera, oro har, lehiakortasunik ez galtzeko informazio estrategikoaren jabe izatea enpresentzat funtsezkoa bada ere, berrikuntza jarduerak aurrera eramateko oraindik ere gailentasun handiagoa dauka. Informazio estrategikoa iturri ezberdinetatik jaso daiteke eta horietako bakoitzari ematen zaion garrantzia ezberdina da. Lan honen helburua erlazio hori aztertzearena izanik, ondoriozta dezakegu, alde batetik, produktuan zein prozesuan berritzen duten enpresek, berrikuntza teknologikoak aurrera eramateko garaian, enpresa barnetik jasotako informazioari ematen diotela garrantzi gehien. Eta bestaldetik, instituzio publikoetatik, hau da, unibertsitate edo goi-ikasketetako zentroetatik, ikerketako erakunde publikoetatik edota zentro teknologikoetatik jasotako informazioari garrantzi gutxi ematen zaiola.

Small-scale aquaculture for rural livelihoods: Proceedings of the Symposium on Small-scale aquaculture for increasing resilience of Rural Livelihoods in Nepal. 5-6 Feb 2009. Kathmandu, Nepal

Over the years, aquaculture has developed as one of the fastest growing food production sectors in Nepal. However, local fish supplies have been extremely inadequate to meet the ever increasing demand in the country. Nepal imports substantial quantities of fish and fish products from India, Bangladesh, Thailand, and elsewhere. Integration of pond aquaculture in existing crop-livestock-based farming system is believed to be effective in increasing local fish supply and diversifying livelihood options of a large number of small-holder farmers in southern plains (terai) and mid-hill valleys, thereby also increasing resilience of rural livelihoods. There is growing appreciation of the role of small-scale aquaculture in household food and nutrition security, income generation, and empowerment of women and marginalized communities. This book includes a total of 25 papers presented at the ‘Symposium on Small-scale Aquaculture for Increasing Resilience of Rural Livelihoods in Nepal’, held in Kathmandu on 5-6 February 2009. The papers cover technological, social, economic and environmental aspects of small-scale aquaculture development emerged from research and development initiatives of governmental, non-governmental and international research organizations in recent decad

Ex-ante assessment of integrated aquaculture-agriculture adoption and impact in Southern Malawi

There are increasing requirements for impact assessment by development partners in order to increase the accountability and effectiveness of research and development projects. Impact assessment research has been dominated by conventional economic methods. This context challenges agricultural research organizations to develop and apply alternative impact assessment methods incorporating economic, social, and environmental impact components. In this study, we use the Tradeoff Analysis for Multi-Dimensional Impact Assessment (TOA-MD) model to evaluate the impact of integrated aquaculture-agriculture (IAA) adoption in Malawi. The study demonstrated that with a minimal data set, the TOA-MD model can be applied to predict and assess the adoption rates of new technologies and practices as well as their economic and non-economic impacts.

Projected impacts of climate change on marine fish and fisheries

This paper reviews current literature on the projected effects of climate change on marine fish and shellfish, their fisheries, and fishery-dependent communities throughout the northern hemisphere. The review addresses the following issues: (i) expected impacts on ecosystem productivity and habitat quantity and quality; (ii) impacts of changes in production and habitat on marine fish and shellfish species including effects on the community species composition, spatial distributions, interactions, and vital rates of fish and shellfish; (iii) impacts on fisheries and their associatedcommunities; (iv) implications for food security and associated changes; and (v) uncertainty andmodelling skill assessment. Climate change will impact fish and shellfish, their fisheries, and fishery-dependent communities through a complex suite of linked processes. Integrated interdisciplinary research teams are forming in many regions to project these complex responses. National and international marine research organizations serve a key role in the coordination and integration of research to accelerate the production of projections of the effects of climate change on marine ecosystems and to move towards a future where relative impacts by region could be compared on a hemispheric or global level. Eight research foci were identified that will improve the projections of climate impacts on fish, fisheries, and fishery-dependent communities.

Viestintäteknologian kehityksen vaikutus organisaation toimintatapoihin ja esimiestyöhön

Tutkimuksen tavoitteena oli selvittää, millä tavoin viestintäteknologian kehitys, globalisaatio sekä organisaatiomuodot ovat suhteessa keskenään sekä miten ne vaikuttavat esimiestyöhön hajautuneessa organisaatiossa. Tutkimuskohteena olivat kymmenen eri asiantuntijaorganisaatiossa esimiesasemassa työskentelevää henkilöä. Tutkimus toteutettiin laadullisin tutkimusmenetelmin. Tutkimusaineisto hankittiin puolistrukturoitujen teemahaastattelujen sekä avoimien haastatteluiden avulla. Tutkimuksen teoreettinen viitekehys rakennettiin hajautuneen organisaation määrittelyn ohella johtamisteorioista sekä organisaation viestinnän teorioista. Tutkimuksen tulosten perusteella hajautuneet organisaatiomuodot yleistyvät uusille toimialoille ja työaika ja –paikka käsitteet muuttuvat. Esimiestyö on sosiaalinen prosessi. Vuorovaikutteinen ja päätösvaltaa jakava esimiestyö on tehokkaan ja joustavan organisaation edellytys. Verkostoituminen on yleistynyt ja on organisaatioiden kannalta järkevämpi tapa saada tarvittava osaaminen käyttöön kuin rekrytoiminen. Tutkimuksen mukaan organisaatiot pyrkivät edesauttamaan verkostoitumista mahdollistamalla työajasta ja –paikasta riippumattoman työn tekemisen. Useimmat organisatioissa käyettävät sovellukset ja järjestelmät toimivat tietoliikenneverkon kautta tai pilvipalveluissa. Työntekijöitä kannustetaan voimakkaasti muodostamaan sekä löytämään omaa ja organisaation osaamista tukevia osaamiskeskuksia. Lisäksi tutkimus vahvistaa aiempien tutkimustulosten mukaisesti, että nykymuotoinen esimiestyö ei toimi työaikaja työpaikkarajoituksista vapautuneessa, hajautuneissa organisaatioissa. Tämän vaikutuksesta myös alaisten rooli muuttuu hajautuneissa organisaatioissa.

Fundos competitivo para o financiamento da pesquisa agrícola no Brasil: o caso do PRODETAB-EMPRAPA

Programas de Fundos Competitivos para financiamento da pesquisa agrícola há muito estão sendo implementados nos países desenvolvidos. Entretanto, somente a partir da década de 1990 a adoção desse mecanismo se intensificou nos países em desenvolvimento, especialmente na América Latina. Isso ocorreu em razão da redução dos recursos do governo federal para a pesquisa agrícola, o que levou as instituições de pesquisa a buscar fontes alternativas para o financiamento de sua programação. A partir desse cenário, o presente trabalho analisa e discute a importância dos Fundos Competitivos como alternativa criativa e inovadora na captação de recursos para o financiamento da pesquisa agrícola no Brasil. A análise é feita a partir de estudo teórico sobre esse mecanismo de financiamento e com base em um estudo de caso do Sistema Competitivo do PRODETAB, implementado e coordenado pela Embrapa. O objetivo foi o de avaliar a importância e a contribuição dos fundos competitivos para o aumento da eficiência na alocação dos recursos públicos para a pesquisa agrícola e para a melhoria da qualidade dos projetos de pesquisa e desenvolvimento

Fundos competitivos para o financiamento da pesquisa agrícola no Brasil: o caso do PRODETAB - Embrapa

Programas de Fundos Competitivos para financiamento da pesquisa agrícola há muito estão sendo implementados nos países desenvolvidos. Entretanto, somente a partir da década de 1990 a adoção desse mecanismo se intensificou nos países em desenvolvimento, especialmente na América Latina. Isso ocorreu em razão da redução dos recursos do governo federal para a pesquisa agrícola, o que levou as instituições de pesquisa a buscar fontes alternativas para o financiamento de sua programação. A partir desse cenário, o presente trabalho analisa e discute a importância dos Fundos Competitivos como alternativa criativa e inovadora na captação de recursos para o financiamento da pesquisa agrícola no Brasil. A análise é feita a partir de estudo teórico sobre esse mecanismo de financiamento e com base em um estudo de caso do Sistema Competitivo do PRODETAB, implementado e coordenado pela Embrapa. O objetivo foi o de avaliar a importância e a contribuição dos fundos competitivos para o aumento da eficiência na alocação dos recursos públicos para a pesquisa agrícola e para a melhoria da qualidade dos projetos de pesquisa e desenvolvimento.

Data information system to promote the organization data of collections - modeling considerations by the Unified Modelign Language (UML)

Pode-se afirmar que a evolução tecnológica (desenvolvimento de novos instrumentos de medição como, softwares, satélites e computadores, bem como, o barateamento das mídias de armazenamento) permite às Organizações produzirem e adquirirem grande quantidade de dados em curto espaço de tempo. Devido ao volume de dados, Organizações de pesquisa se tornam potencialmente vulneráveis aos impactos da explosão de informações. Uma solução adotada por algumas Organizações é a utilização de ferramentas de sistemas de informação para auxiliar na documentação, recuperação e análise dos dados. No âmbito científico, essas ferramentas são desenvolvidas para armazenar diferentes padrões de metadados (dados sobre dados). Durante o processo de desenvolvimento destas ferramentas, destaca-se a adoção de padrões como a Linguagem Unificada de Modelagem (UML, do Inglês Unified Modeling Language), cujos diagramas auxiliam na modelagem de diferentes aspectos do software. O objetivo deste estudo é apresentar uma ferramenta de sistemas de informação para auxiliar na documentação dos dados das Organizações por meio de metadados e destacar o processo de modelagem de software, por meio da UML. Será abordado o Padrão de Metadados Digitais Geoespaciais, amplamente utilizado na catalogação de dados por Organizações científicas de todo mundo, e os diagramas dinâmicos e estáticos da UML como casos de uso, sequências e classes. O desenvolvimento das ferramentas de sistemas de informação pode ser uma forma de promover a organização e a divulgação de dados científicos. No entanto, o processo de modelagem requer especial atenção para o desenvolvimento de interfaces que estimularão o uso das ferramentas de sistemas de informação.

Políticas educacionais e gestão democrática na escola

Pós-graduação em Educação - FFC

The drivers and implications of environmental innovations: European evidence at different levels of analysis

The present work is a collection of three essays devoted at understanding the determinants and implications of the adoption of environmental innovations EI by firms, by adopting different but strictly related schumpeterian perspectives. Each of the essays is an empirical analysis that investigates one original research question, formulated to properly fill the gaps that emerged in previous literature, as the broad introduction of this thesis outlines. The first Chapter is devoted at understanding the determinants of EI by focusing on the role that knowledge sources external to the boundaries of the firm, such as those coming from business suppliers or customers or even research organizations, play in spurring their adoption. The second Chapter answers the question on what induces climate change technologies, adopting regional and sectoral lens, and explores the relation among green knowledge generation, inducement in climate change and environmental performances. Chapter 3 analyzes the economic implications of the adoption of EI for firms, and proposes to disentangle EI by different typologies of innovations, such as externality reducing innovations and energy and resource efficient innovations. Each Chapter exploits different dataset and heterogeneous econometric models, that allow a better extension of the results and to overcome the limits that the choice of one dataset with respect to its alternatives engenders. The first and third Chapter are based on an empirical investigation on microdata, i.e. firm level data extracted from innovation surveys. The second Chapter is based on the analysis of patent data in green technologies that have been extracted by the PATSTAT and REGPAT database. A general conclusive Chapter will follow the three essays and will outline how each Chapter filled the research gaps that emerged, how its results can be interpreted, which policy implications can be derived and which are the possible future lines of research in the field.