Regimen sanitatis Salernitanum ([Reprod.])

[Regimen sanitatis Salernitanum (latin). 1493]

Regimen sanitatis salerni, sive, Scholae salernitanae de conservanda bona valetvdine praecepta

Includes bibliographical footnotes.

Regimen sanitatis

Incipit Regimen sanitatis salernitanû ... pro côseruatione sanitatis totius humani generis a magistro arnaldi de Villanoua Cathellano ... ; ueraciter expositû nouiter correctû ac emendatû p[er] ... doctores Montispessulani ...Anno MCCCCLXXX p[re]dicto loco actu mora trahentes; al fin: Hoc opus optatur quod Flos medicine vocatur

Regimen Sanitatis von heinrich von Loufenberg, ein mittelhochdeutsches Gedicht untersucht und erlautert.

Thesis (doctoral)--Kaiser-Wilhelms-Universitat Strassburg.

De conservanda bona valetudine opusculum Scholae Salernitanae ([Reprod.]) / cum Arnoldi Novicomensis, medici & philosophi antiqui enarrationibus utilissimis ; denuo recognitis & auctis per Joan. Curionem & Jacob Crellium

[Regimen sanitatis Salernitanum (latin). 1553]

Retardement de la mort par bon régime ou Conservation de santé ([Reprod.]) / Jadis envoyé par l'Escole de Salerne au Roi d'Angleterre ; trad. de latin en rithme françoise par Geoffroy Le Tellier,...

[Regimen sanitatis Salernitanum (français moyen). 1561]

L'art de conserver sa santé, composé par l'Ecole de Salerne,

Includes Latin text of the Regimen.

Fragments de plusieurs manuscrits.

"Tractatus kilindri" (2). — Notes sur Juvénal (17). — "Interpretationes diversorum nominum propriorum (35). — Tractatulus orthographie, [auct. Francisco de Monte Leonis] (40v). — [De purgatorio] (59). — [Cicero, de officiis] (70). — Epistola Florentinorum contra Pisanos, a. 1405 (81). — Passio secundum fr. Joh. de Sancto Geminiano (82). — Regimen sanitatis Salerni (94). — Liber Theolophori de cognitione scismatis" (100). — Prophéties sur les papes (131), avec figures.

A prime-boost immunisation regimen using recombinant BCG and Pr55 gag virus-like particle vaccines based on HIV type 1 subtype C successfully elicits Gag-specific responses in baboons

Mycobacterium bovis BCG is considered an attractive live bacterial vaccine vector. In this study, we investigated the immune response of baboons to a primary vaccination with recombinant BCG (rBCG) constructs expressing the gag gene from a South African HIV-1 subtype C isolate, and a boost with HIV-1 subtype C Pr55 gag virus-like particles (Gag VLPs). Using an interferon enzyme-linked immunospot assay, we show that although these rBCG induced only a weak or an undetectable HIV-1 Gag-specific response on their own, they efficiently primed for a Gag VLP boost, which strengthened and broadened the immune responses. These responses were predominantly CD8+ T cell-mediated and recognised similar epitopes as those targeted by humans with early HIV-1 subtype C infection. In addition, a Gag-specific humoral response was elicited. These data support the development of HIV-1 vaccines based on rBCG and Pr55 gag VLPs. © 2009 Elsevier Ltd. All rights reserved.

A 250 μg/week dose of vitamin D was as effective as a 50 μg/d dose in healthy adults, but a regimen of four weekly followed by monthly doses of 1250 μg raised the risk of hypercalciuria

The risk of vitamin D insufficiency is increased in persons having limited sunlight exposure and dietary vitamin D. Supplementation compliance might be improved with larger doses taken less often, but this may increase the potential for side effects. The objective of the present study was to determine whether a weekly or weekly/monthly regimen of vitamin D supplementation is as effective as daily supplementation without increasing the risk of side effects. Participants were forty-eight healthy adults who were randomly assigned for 3 months to placebo or one of three supplementation regimens: 50 μg/d (2000 IU/d, analysed dose 70 μg/d), 250 μg/week (10 000 IU/week, analysed dose 331 μg/week) or 1250 μg/week (50 000 IU/week, analysed dose 1544 μg/week) for 4 weeks and then 1250 μg/month for 2 months. Daily and weekly doses were equally effective at increasing serum 25-hydroxyvitamin D, which was significantly greater than baseline in all the supplemented groups after 30 d of treatment. Subjects in the 1250 μg treatment group, who had a BMI >26 kg/m2, had a steady increase in urinary Ca in the first 3 weeks of supplementation, and, overall, the relative risk of hypercalciuria was higher in the 1250 μg group than in the placebo group (P= 0·01). Although vitamin D supplementation remains a controversial issue, these data document that supplementing with ≤ 250 μg/week ( ≤ 10 000 IU/week) can improve or maintain vitamin D status in healthy populations without the risk of hypercalciuria, but 24 h urinary Ca excretion should be evaluated in healthy persons receiving vitamin D3 supplementation in weekly single doses of 1250 μg (50 000 IU).

Radiosensitizing effect of electrochemotherapy in a fractionated radiation regimen in radiosensitive murine sarcoma and radioresistant adenocarcinoma tumor model

Radiosensitizing Effect of Electrochemotherapy in a Fractionated Radiation Regimen in Radiosensitive Murine Sarcoma and Radioresistant Adenocarcinoma Tumor Model. Electrochemotherapy can potentiate the radiosensitizing effect of bleomycin, as shown in our previous studies. To bring this treatment closer to use in clinical practice, we evaluated the interaction between electrochemotherapy with bleomycin and single-dose or fractionated radiation in two murine tumor models with different histology and radiosensitivity. Radiosensitive sarcoma SA-1 and radioresistant adenocarcinoma CaNT subcutaneous tumors grown in A/J and CBA mice, respectively, were used. The anti-tumor effect and skin damage around the treated tumors were evaluated after electrochemotherapy with bleomycin alone or combined with single-dose radiation or a fractionated radiation regimen. The anti-tumor effectiveness of electrochemotherapy was more pronounced in SA-1 than CaNT tumors. In both tumor models, the tumor response to radiation was not significantly influenced by bleomycin alone or by electroporation alone. However, electrochemotherapy before the first tumor irradiation potentiated the response to a single-dose or fractionated radiation regimen in both tumors. For the fractionated radiation regimen, normal skin around the treated tumors was damaged fourfold less than for the single-dose regimen. Electrochemotherapy prior to single-dose irradiation induced more damage to the skin around the treated tumors and greater loss of body weight compared to other irradiated groups, whereas electrochemotherapy combined with the fractionated radiation regimen did not. Electrochemotherapy with low doses of bleomycin can also be used safely for radiosensitization of different types of tumors in a fractionated radiation regimen, resulting in a good anti-tumor effect and no major potentiating effect on radiation-induced skin damage. © 2009 by Radiation Research Society.