Adaptation of AHRQ patient safety indicators for use in ICD-10 administrative data by an international consortium.

Objective: The Agency for Healthcare Research and Quality (AHRQ) developed Patient Safety Indicators (PSIs) for use with ICD-9-CM data. Many countries have adopted ICD-10 for coding hospital diagnoses. We conducted this study to develop an internationally harmonized ICD-10 coding algorithm for the AHRQ PSIs. Methods: The AHRQ PSI Version 2.1 has been translated into ICD-10-AM (Australian Modification), and PSI Version 3.0a has been independently translated into ICD-10-GM (German Modification). We converted these two country-specific coding algorithms into ICD-10-WHO (World Health Organization version) and combined them to form one master list. Members of an international expert panel-including physicians, professional medical coders, disease classification specialists, health services researchers, epidemiologists, and users of the PSI-independently evaluated this master list and rated each code as either "include," "exclude," or "uncertain," following the AHRQ PSI definitions. After summarizing the independent rating results, we held a face-to-face meeting to discuss codes for which there was no unanimous consensus and newly proposed codes. A modified Delphi method was employed to generate a final ICD-10 WHO coding list. Results: Of 20 PSIs, 15 that were based mainly on diagnosis codes were selected for translation. At the meeting, panelists discussed 794 codes for which consensus had not been achieved and 2,541 additional codes that were proposed by individual panelists for consideration prior to the meeting. Three documents were generated: a PSI ICD-10-WHO version-coding list, a list of issues for consideration on certain AHRQ PSIs and ICD-9-CM codes, and a recommendation to WHO to improve specification of some disease classifications. Conclusion: An ICD-10-WHO PSI coding list has been developed and structured in a manner similar to the AHRQ manual. Although face validity of the list has been ensured through a rigorous expert panel assessment, its true validity and applicability should be assessed internationally.

Identidad en tránsito : la interpretación cultural y la puesta en valor del patrimonio intangible

Programa de Doctorado: Fuentes, Métodos e Historiografía para la Investigación en el Mundo Atlántico

Mémoires touchant la vie les éscrits de Marie de Rabutin-Chantal, dame de Bourbilly, marquise de Sévigné /

Vol.6: Notes et d'éclaircissement par M. Aubenas.

El arte mimético como forma de conocimiento : Las críticas de Jean-Marie Schaeffer a Platón

Fil: Rosengurt, Chantal Paula. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

El arte mimético como forma de conocimiento : Las críticas de Jean-Marie Schaeffer a Platón

Fil: Rosengurt, Chantal Paula. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

COEXISTENCE OF TWO CHRONIC NEUROPATHIES IN A YOUNG CHILD: CHARCOT-MARIE-TOOTH DISEASE TYPE 1A AND CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY

We report an 18-month-old Charcot-Marie-Tooth type 1A (CMT1A) patient who developed a rapid-onset neuropathy, with proximal and distal weakness, and non-uniform nerve conduction studies. The neuropathy responded well to immunomodulation, confirming the coexistence of an inherited and an inflammatory neuropathy. Unexpected clinical and/ or electrophysiological manifestations in CMT1A patients should alert clinicians to concomitant inflammatory neuropathy. In addition, this association raises reflections about disease mechanism in CMT1A. Muscle Nerve 42: 598-600, 2010

Compound Charcot-Marie-Tooth disease may determine unusual and milder phenotypes

Compound forms of Charcot-Marie-Tooth (CMT) disease have been recently associated with unusually severe neuropathies, an observation that prompted the proposition that the additive effects of two mutations should be searched in patients whose clinical severity falls outside the common CMT phenotypes. In this report, we present a father and a daughter with a very mild and unusual disease that segregates with two mutations in PMP22 gene, the 17p11.2-p12 duplication and a Ser72Leu point mutation. We propose that the deleterious effects of each mutation are partially compensated by the functional effect of the other.

Characterizing the phenotypic manifestations of MFN2 R104W mutation in Charcot-Marie-Tooth type 2

Mutations of the mitofusin 2 (MFN2) gene have been reported to be the most common cause of the axonal form of Charcot Marie Tooth disease (CMT). The aim of this study was to describe a de novo MFN2 p.R104W mutation and characterize the associated phenotype. We screened the entire coding region of MFN2 gene and characterized its clinical phenotype, nerve conduction studies and sural nerve biopsy. Neuropsychological tests and brain MRI were also performed. A de nova mutation was found in exon 4 (c.310C > T; p.R104W). In addition to a severe and early onset axonal neuropathy, the patient presented learning problems, obesity, glucose intolerance, leukoencephalopathy, brain atrophy and evidence of myelin involvement and mitochondrial structural changes on sural nerve biopsy. These results suggest that MFN2 p.R104W mutation is as a hot-spot for MFN2 gene associated to a large and complex range of phenotypes. (C) 2011 Elsevier B.V. All rights reserved.

Review of Voices from the shopfloor: Dramas of the employment relationship,/by Anne-Marie Greene. Aldershot : Ashgate, 2001

This research monograph seeks, as the author puts it, ‘to demonstrate the utility of ethnographic research methods to industrial relations in the developing world’. To this end, the author provides case studies of two lock factories in the West Midlands of England, with data sourced from interviews and observations by the author during a period of two decades in the case of one, and a rather shorter period in the case of the other. The insights gleaned from these two case studies are then considered in the light of the ethnographic literature on industrial relations in the developing world. The body of the book comprises three main chapters which successively examine the issues of paternalism, gender and family, and collective action in the two factories.

Um sobrevôo no "Caso Marie Curie": um experimento de antropologia, gênero e ciência

O presente artigo visa fazer uma releitura do "Caso Marie Curie" sob o signo do acontecimento. O intuito, assim, é explorar relações constituintes da controvérsia que se desdobrou no prêmio Nobel de 1903, que laureou a descoberta da radioatividade e de elementos radioativos. A porta de entrada, para tal empreitada, serão as mediações entre as relações de gênero e os não-humanos mobilizados nos laboratórios. Baseado nessas mediações, descrevo a diferença de possibilidades masculino/feminina em fazer-existir a Natureza em relação ao poder que a definição de gênero dá a uns em detrimento de outros, mas também como ao fazer-existir a radioatividade constituiu-se um devir, que fez essa relação gaguejar, mudando-a de sentido. O "Caso Marie Curie" torna imediatamente inseparável dois domínios: tanto o envolvimento das relações de gênero na produção científica quanto o envolvimento da ciência nas relações de gênero. Esse acontecimento ressoa para abordagens antropológicas e feministas da ciência. Assim, coloco-as em discussão na medida em que as relações de poder fizeram-me respeitar o devir que o ofício da cientista pôs em cena: a radioatividade.