Botrychium matricariifolium A. Br. ex Koch, una nova espècie per a la flora del massís del Montseny = Botrychium matricariifolium A. Br. ex Koch, a new species for the flora of the Montseny massif (NE Iberian Peninsula)

Nota breu sobre la descripció de Botrychium matricariifolium A. Br. ex Koch al massís del Montseny

Estado actual del conocimiento de la pteridoflora de la provincia de Murcia

Se sintetizan los datos publicados sobre la pteridoflora de la provincia de Murcia y se aporta un gran número de nuevas citas cuyos pliegos-testigo están depositados en el herbario de la Universidad de Murcia. Para cada especie se realiza un mapa de distribución en Murcia, utilizando por vez primera el mapa matriz de la provincia con cuadrículas UTM de 10 Km de lado. Son citas a destacar como nuevas para la provincia: Asplenium obovatum V i v ., Cheilanthes maderensis Lowe, Equisetum arvense L. y Selagineila denticulata (L.) Link; y, por ser especie poco citada: Asplenium onopteris L.

Synthetic approaches towards the Lycopodium alkaloids

The Lycopodium alkaloids are a structurally diverse group of natural products isolated from Lycopodium with important biological effects for the potential treatment of cancer and severe neurodegenerative diseases. To date, full biological studies have been hampered by lack of material from natural sources. Total synthesis represents a possible solution to meet this demand as well as the most effective way to design new compounds to determine structural activity relationships and obtain more potent compounds. The aim of this chapter is to summarise the work carried out in this field so far by presenting an overview of the synthetic strategies used to access each of the four key Lycopodium alkaloid types. Particular emphasis has been placed on methods that rapidly construct each nucleus utilizing tandem reactions.

Synthetic approaches towards the Lycopodium alkaloids

The Lycopodium alkaloids are a structurally diverse group of natural products isolated from Lycopodium with important biological effects for the potential treatment of cancer and severe neurodegenerative diseases. To date, full biological studies have been hampered by lack of material from natural sources. Total synthesis represents a possible solution to meet this demand as well as the most effective way to design new compounds to determine structural activity relationships and obtain more potent compounds. The aim of this chapter is to summarise the work carried out in this field so far by presenting an overview of the synthetic strategies used to access each of the four key Lycopodium alkaloid types. Particular emphasis has been placed on methods that rapidly construct each nucleus utilizing tandem reactions.